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Postdoctoral Positions at HMS


Biological Chemistry and Molecular Pharmacology | Biomedical Informatics | Cell Biology | Center for Bioethics | Genetics | Global Health and Social Medicine | Health Care Policy | Microbiology and Immunobiology | Neurobiology | Systems Biology | Harvard School of Dental Medicine | Wyss Institute


This page lists some of the postdoctoral positions currently available on the HMS Quadrangle. Many principal investigators do not advertise their postdoctoral positions with us, so if the PI you want to work with isn't listed here, please contact her/him directly. Please do not send your CV to the administrator of this page.

Quad Departments: to have an opportunity listed on this page, send along a description of the postdoctoral position and contact information to us at postdoc_office@hms.harvard.edu.

Postdoc openings at other Harvard affiliated institutions:
Beth Israel Deaconess Medical Center | Brigham & Women's Hospital | Children’s Hospital | Dana-Farber | Joslin | Mass General Hospital * | McLean Hospital* | T.H. Chan School of Public Health*
*Please note: some Harvard affiliates do not advertise individual postdoc positions with us, it may be best to identify a PI conducting work in your specific area of interest, and to email that PI directly with your CV and cover letter.

 


~FEATURED FELLOWSHIP OPPORTUNITIES~


The Dean's Postdoctoral Fellowship
Co-Sponsored by: The Office for Diversity Inclusion and Community Partnership and The Office for Postdoctoral Fellows

As part of an effort to promote a diversity of backgrounds, perspectives, and experiences among its faculty and trainees, Harvard Medical School invites applications for the Dean’s Postdoctoral Fellowship.

The Office for Diversity Inclusion and Community Partnership in collaboration with The Office for Postdoctoral Fellows will award two-year postdoctoral fellowships per year to two promising researchers in the fields of basic or social sciences. The Dean’s Postdoctoral Fellowship at Harvard Medical School will prepare postdoctoral scientists, particularly scientists from minority and disadvantaged backgrounds, for cutting-edge research careers.  This fellowship will position the right candidate to make major contributions as scientific and societal leaders.

Fellows will benefit from a highly innovative and creative research environment that emphasizes scientific rigor, collaboration, and the pursuit of excellence in science.

For more info or to apply: http://www.hms.harvard.edu/dcp/deanspdfellowship/index.html

 

DEPARTMENTAL LISTINGS

BIOLOGICAL CHEMISTRY AND MOLECULAR PHARMACOLOGY

Blacklow Laboratory at Harvard Medical School
The Blacklow Laboratory at Harvard Medical School (Department of Biological Chemistry and Molecular Pharmacology) has an opening for a Postdoctoral position. The laboratory currently investigates structure-function relationships in Notch signaling, its downstream targets, and its epigenetic regulators.

Applicants should possess a Ph.D. and/or M.D. degree in Molecular Biology, Cell Biology, Biochemistry, Structural Biology or a related field.

Interested individuals should send a cover letter, curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to jobs_blacklowlab@hms.harvard.edu.

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BIOMEDICAL INFORMATICS

Avillach Laboratory at Harvard Medical School

Research Fellow Position at the Department of Biomedical Informatics (posted 10/16/15)

Description: The Department of Biomedical Informatics (DBMI) at Harvard Medical School is looking for a Research Fellow to help us build cutting edge research platforms. We seek an individual to work on our multidisciplinary team of data scientists, medical doctors, and developers. Our team studies large and disparate datasets from the domains of biology, healthcare and social media. The goal of our efforts is to transform healthcare and research to usher in a new age of individualized data driven medicine.
The Research Fellow will be responsible for developing novel methodologies and applications to help visual causal relationships in bioinformatics data sets. The diversity of subject matter will require a creative mind and a candidate capable of deploying imaginative strategies and who is dedicated to solving complex and challenging problems within an interdisciplinary environment.
Specific responsibilities for this position include:
• Work to understand data about causal relationships in order to develop visualizations.
• Create prototypes for visualizations and work with software professionals to integrate the work into an existing platform.
• Perform novel research on bioinformatics data sets and publish any findings.

Basic Requirements: PhD degree (or MD/PhD.) in Biomedical Informatics, Bioinformatics, Computational Biology, Computer Science, Mathematics, or a related field; Curriculum in and/or experience with demonstrated ability to extract insight from large volumes of data using data mining and the creation of effective visualization techniques; Experience in programming and software development; Excellent written and verbal communication skills.
Additional Requirements: Experience with user interaction design; JavaScript; D3 visualization library (Or similar); Data mining; R, Python, and/or Perl is desirable.
Harvard Medical School is an Equal Opportunity/Affirmative Action Employer. Women and minorities are especially encouraged to apply.
For additional information contact: http://avillach-lab.hms.harvard.edu

 

Gehlenborg Laboratory at Harvard Medical School

Multiple postdoctoral fellowships are available immediately in the Gehlenborg Lab in the Department of Biomedical Informatics at Harvard Medical School. (posted 10/21/15)

Description:
The goal of the lab is to improve human health by developing computational techniques and interfaces that enable biomedical and clinical investigators to efficiently interact with biomedical data. We design, implement and evaluate methods and tools that leverage the knowledge and cognitive skills of investigators in order to enable the interpretation of massive heterogeneous data sets that integrate genomic and clinical data. Please see http://gehlenborglab.org for additional information about our work.

Possible research projects include development of data visualization, analysis, and management tools to study genomic structural variants, dynamics of the 3D genome, and cancer subtypes in patient cohorts. Further projects involve the design and implementation of visual exploration tools for biomedical data repositories and tools for viewing and interacting with provenance graphs. All of the projects are highly interdisciplinary and are being conducted in close cooperation with computational or experimental domain experts providing an excellent opportunity for collaborative research.

Our lab in the Department of Biomedical Informatics is part of a vibrant community of scientists, physicians, and engineers whose goal is to advance the boundaries of knowledge. The Department has recently been formed at Harvard Medical School to lead development of computational and informatics techniques to address pertinent challenges in modern biological sciences and medicine. The Department’s faculty conduct research at the intersection of biomedicine and information sciences, including bioinformatics, functional genomics, translational medicine, and clinical knowledge management. Based on the Harvard Medical School Longwood Campus, it provides a rich scientific environment, with many seminar series and invited speakers of the highest caliber.

Responsibilities:
The postdoctoral fellows will be responsible for developing novel methodologies and applications to facilitate visual analysis of massive heterogeneous biomedical data sets, including genomic and clinical data. While the focus of the positions is on the development of visualization approaches, the roles will also involve the integration of such tools with data analysis and data management tools.
Other responsibilities include day-to-day project management, including coordination with collaborators and other team members, as well as the writing of manuscripts. Contribution to the grant writing efforts of the lab are expected.

Basic Requirements:
Candidates must have a PhD degree in a quantitative field such as bioinformatics, computational biology, biomedical informatics, medical informatics, computer science or related fields and a track-record of publication in the top journals or conferences of their field. Hands-on experience with management, analysis, and visualization of biomedical data as well as experience in developing (web-based) interactive software tools are required for this position. Excellent programming skills and working knowledge of state-of-the-art software development techniques are essential. The candidates interested in these positions must be highly motivated, willing to learn and demonstrate initiative in assigned tasks. Excellent written and verbal communication skills are crucial.

Additional Requirements:
Experience with Python, JavaScript, web application development and cloud computing are desirable. Previous research experience in areas such as epigenomics or cancer genomics will be beneficial.

Terms:
The positions are available immediately and can be renewed annually.

How to apply:
Candidates should submit their CV, a research statement, PDFs of their three best papers, and contact information for three references to nils@hms.harvard.edu with [POSTDOC] in the subject.

Harvard Medical School is an Equal Opportunity/Affirmative Action Employer. Women and minorities are especially encouraged to apply.

 

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CELL BIOLOGY

Yuan Laboratory at Harvard Medical School
The Yuan laboratory at Harvard Medical School (Department of Cell Biology) has an immediate opening for a postdoctoral scientist. Our laboratory investigates the molecular mechanisms of cell death, including necroptosis and apoptosis, and their relevance for human diseases. This position is for a highly motivated individual with considerable experience in cell biology or related field. Experience in animal models of human diseases is desirable but not required.

Applicants should possess a Ph.D. and/or M.D. degree in molecular biology, cell biology, biochemistry, or neurobiology and a strong publication record. Interested individuals should send a curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to junying_yuan@hms.harvard.edu.

For additional information please visit our webpage: https://yuan.med.harvard.edu/


Liao Laboratory at Harvard Medical School

The Liao laboratory at Harvard Medical School (Department of Cell Biology) has an opening for a postdoctoral scientist. Our laboratory uses high-resolution single-particle electron cryo-microscopy (cryo-EM) to study the structure and function of membrane proteins. We seek a highly motivated individual with considerable experience in membrane protein biochemistry and is interested in learning cryo-EM techniques. Experience in X-ray crystallography is desirable but not required.

Applicants should possess a Ph.D. and/or M.D. degree in Molecular Biology, Cell Biology, Biochemistry, Structural Biology or a related field. Interested individuals should send a curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to maofu_liao@hms.harvard.edu.

For additional information please visit our webpage: http://liao.hms.harvard.edu/

 

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CENTER FOR BIOETHICS

Postdoctoral Research Scholars Program - Center for Bioethics at Harvard Medical School

The Center for Bioethics at Harvard Medical School invites applications for the Postdoctoral Research Scholars Program in Bioethics, for appointments commencing in summer 2016. This two-year program aims to prepare scholars with the knowledge and skills necessary to become leaders in the field of bioethics. Research Scholars will be fully integrated into the community of scholars at the Center for Bioethics, with access to the resources of the entire Medical School and the University at large.
Scholars will receive an annual stipend, benefits, and an allotment for academic expenses and travel.
The core experience will include:

  • Mentored research. Postdoctoral Research Scholars will work closely with faculty mentors from across the University to develop and conduct original research in the field of bioethics. A primary aim of the Postdoctoral Research Scholarship is to prepare candidates with the knowledge and skills necessary to obtain competitive research funding and to develop a successful academic career in bioethics.
  • Educational opportunities. Since Postdoctoral Research Scholars will arrive with a diverse background of experience and knowledge, each candidate will work with the faculty to develop a customized educational program to ensure that they develop expertise across the field of bioethics as a whole, as well as in-depth knowledge related to their special areas of interest. As such, the Postdoctoral Research Scholars will have opportunities to access the Center’s courses and seminars, as well as the potential to audit relevant courses across the University with faculty permission.
  • Community Life. Postdoctoral Research Scholars will be fully engaged with the activities of the Center and the Harvard-affiliated teaching hospitals. They will take responsibility for organizing and conducting conferences and seminars, and will be asked to assist in teaching courses in their areas of interest. They will have opportunities to participate on hospital Clinical Ethics Committees and Institutional Review Boards. In short, the Postdoctoral Research Scholarship seeks to provide the candidates with the greatest possible access to all that Harvard University has to offer.

Application Requirements
Applications are invited from scholars who have or will have completed a doctoral degree (MDs, JDs, PhDs or equivalent) by June 1, 2016. Doctorates may be in any relevant field, including but not limited to public health, psychology, economics, philosophy, sociology anthropology, or anthropology. The deadline for summer or fall 2016 is May 2, 2016. Applications are considered throughout the year under special circumstances.
A completed application includes each of the following:

  • This application completed and submitted: https://hms.az1.qualtrics.com/jfe/form/SV_1ZjNDHt25YqQ0DP
  • A curriculum vitae
  • A personal statement (maximum 1000 words) that describes the applicant’s interest in the Research Scholars Program and what the applicant hopes to achieve from the program.
  • A published or unpublished writing sample for which the candidate is the sole or lead author.
  • In addition, applicants should arrange for 3 letters of reference to be submitted directly to Prof. Robert Truog by individuals who know the applicant well and who can comment on the candidate’s qualifications and suitability for the Research Scholars Program. Letters should be submitted using the Letter of Reference form found here: http://bioethics.hms.harvard.edu/sites/g/files/mcu336/f/Letter-of-reference-form.pdf
For additional information about the program contact the Center for Bioethics at bioethics_postdoc@hms.harvard.edu or the main office number at 617-432-2570.

 

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GENETICS

Yanker Laboratory at Harvard Medical School
Positions available to study gene regulation, epigenetics and the molecular biology of aging and neurodegenerative diseases.  Projects focus on iPS cells, C. elegans, animal models and the biology of genes involved in aging and Alzheimer's disease. For reference see: Nature 507:448, 2014, J. Cell Biol. 203:457, 2013, Mol. Cell 40:333, 2010, Nature 464:529, 2010, Nature 429:883, 2004. Experience in molecular biology is required.

Send CV, a brief description of research experience and names of 3 references to: Dr. Bruce Yankner by email to aharwick@genetics.med.harvard.edu


Sinclair Laboratory at Harvard Medical School

Post-doctoral Scientist - position available immediately (10.14.15)
We are seeking a talented, highly motivated individual to join the laboratory headed by Professor David Sinclair in the Genetics Department at Harvard Medical School, Boston. The Sinclair lab is known for their work on genes and small molecules that delay aging with a focus on Sirtuins and small molecule activators such as resveratrol. The laboratory has a record of innovation with over 30 patents and numerous start-up companies. In 2014, Dr. Sinclair was on the TIME100 list of the “most influential people in the world.”
The individual will design and conduct laboratory research under the direction of the lab head to identify natural and synthetic small molecules to delay and reverse aging, with a focus on skin aging. The individual will present regular updates to academic and industry collaborators as well as prepare and publish research reports. Candidate may occasionally be required to travel within the U.S. and overseas.
The ideal candidate will have a record of scientific rigor, creativity, and ability to work in teams, with a strong publication record in peer-reviewed scientific journals. Candidate should have a strong background in enzymology, biochemistry, and molecular biology, and be familiar with microbial genetics and mammalian cell culture. Excellent oral and written communication skills are required. The individual will be required to work efficiently as part of an international team with performance measures and time constraints. Proficiency in French is desirable but not essential.
Harvard Medical School Harvard Medical School - Genetics Dept. - salary commensurate with experience
To apply: http://jobs.sciencecareers.org/job/382649/post-doctoral-scientist/#apply-form

The Sinclair laboratory at Harvard Medical School (Departments of Pathology and Genetics) has immediate openings for Postdoctoral Scientists. The laboratory studies genes and small molecules that can slow the pace of aging and age-related diseases. Various projects are available, including studies of neurological diseases, cancer, type I and type II diabetes, muscle metabolism and mitochondria, inflammation, and fertility. Applicants should possess a Ph.D. and/or M.D. degree in Molecular Biology, Cell Biology, Biochemistry or a related field. Training in mammalian cell biology and/or physiology is highly desirable though not essential.

Interested individuals should send a cover letter, curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to david_sinclair@hms.harvard.edu.


Seidman Laboratory at Harvard Medical School
The Seidman lab in the HMS Department of Genetics has a joint postdoctoral position available in the area of human genetics and computational genomics. Our lab uses high throughput DNA sequence analysis to identify genetic variants that are responsible cardiac disease. We are currently integrating results from genome-wide association studies, RNA expression analyses and DNA sequence analyses to identify gene variants responsible for cardiac phenotypes. We seek a highly motivated individual with considerable computational experience as well as molecular biology experience that is interested in integrating diverse data sources to gain mechanistic insights into atrial fibrillation. The ideal applicant will have experience with computational genomics, databases, and statistical inference, as well as molecular biological techniques.

In addition a strong publication record and an ability to work in team settings is essential. Please submit a cover letter detailing your research motivations and a CV with three references to Susanne Bartlett (bartlett@genetics.med.harvard.edu)

 

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GLOBAL HEALTH AND SOCIAL MEDICINE

Global Health Equity Research Fellowship at Harvard Medical School
The Department of Global Health and Social Medicine is seeking a post-doctoral fellow for the two-year Global Health Equity (GHE) Research Fellowship. The Fellow will join the Harvard Medical School Global Health Research Core, directed by Professor Megan Murray, and will be based at a Partners In Health-supported site in Rwanda joining a multidisciplinary team of practitioners, program managers, policy makers, and researchers. During the fellowship, the fellow will conduct high quality research on health needs and program implementation and support a broader research capacity building program and the mentoring of junior researchers in research methods and results dissemination.

Implementation, operational, and scientific research is a principal mission of the HMS Global Health Research Core and Partners In Health. In 2012, Partners In Health-Rwanda, with the support of the Research Core, launched a comprehensive research capacity building program with the aim to cultivate a culture of research and develop technical skills and research leadership at Global Health Delivery Partnership-supported sites. The research spans a variety of health topics aimed at improving service delivery and health outcomes in Rwanda and in other low and middle income countries. Priority research areas for Partners In Health-Rwanda include women’s health, oncology, non-communicable diseases, HIV, maternal and child health, nutrition, and health systems strengthening. The GHE Research Fellow will develop research within a priority research area(s) and support research capacity building within this topic area.

Successful candidates will have recently completed the PhD (or equivalent) in public health, epidemiology, biostatistics, global health, or a related field. Applicants should have 1) strong quantitative skills, 2) strong scientific writing and communication skills, and 3) previous teaching experience. Experience living/working in a cross-cultural environment and French fluency are preferred.

The appointee would be employed by Partners In Health.

Interested applicants should send their CV, cover letter, and contact information for three references to Rebecca Grow (email: ghsm@hms.harvard.edu).

Applications will be reviewed on a rolling basis until the position is filled. The application period is expected to close by December 1, 2015, but may be extended if necessary.

For additional information see:
HMS Global Health Research Core
Global Health Delivery Partnership
Partners In Health

 

Global Health Research Core Position - Research Associate - Biostatistician
The Department of Global Health and Social Medicine seeks a biostatistician to join the Research Core. The Research Core is responsible for the design, implementation, and reporting of research projects carried out in ten countries. The Core provides support for several large NIH-funded studies in addition to numerous smaller projects. These include observational studies, genomic and transcriptomics studies, clinical trials, meta-analyses, and cross sectional surveys as well as teaching and development of statistical methods. The application period is expected to close by December 1, 2015, but may be extended if necessary.

Role: The Biostatistician will work with the Core and Principal Investigators of specific grants on the design, analysis and reporting of medical research projects. The Biostatistician will directly report to the Core Director.

Duties and key responsibilities: The Biostatistician helps develop funding applications and research protocols. S/he conducts complex statistical analyses, prepares material for analysis, and
-Performs sample size/power calculations
-Prepares statistical analysis plans
-Prepares derived datasets for the analyses
-Programs and validates statistical analyses
The Biostatistician prepares and delivers reports for interim and final analyses. S/he contributes to the interpretation and publication of research results. This position also has teaching and advising responsibility, including provision of statistical advice to Core and other researchers, offering short courses and seminars to develop internal capacity in biostatistics, and supervising master’s and PhD students. The Biostatistician is expected to keep up to date with new statistical methods and to actively develop professional networks with peer statisticians locally and internationally. The Biostatistician participates in team meetings and other activities of the Core.

Requirements: Qualified applicants hold a doctoral degree in epidemiology and/or statistics and have at least one-year experience as a statistician in medical research. They also have:
-Excellent working knowledge of STATA and R software
-In-depth understanding of probability and statistics theory
-Applied knowledge of advanced statistical models, such as generalized linear models, survival analyses and mixed models
The position also requires:
-Experience in team coordination
-Strong focus on quality and timely delivery of work
-Excellent organization and time management skills
-Strong problem solving and analytical skills
-Excellent interpersonal skills with high level of proficiency in English
-Strong leadership and mentoring skills

Instructions: Applicants should send a cover letter, curriculum vitae, and names and contact information for at least three potential references. These documents should be emailed to ghsm@hms.harvard.edu. The subject line of the email should state: Core biostatistician.  Applications will be reviewed on a rolling basis until the position is filled. The application period is expected to close by December 1, 2015, but may be extended if necessary.

Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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HEALTH CARE POLICY
No positions currently listed.

 

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MICROBIOLOGY AND IMMUNOBIOLOGY

Gack Laboratory at Harvard Medical School
Two postdoctoral positions are available immediately in the laboratory of Dr. Michaela Gack at the Department of Microbiology and Immunobiology of Harvard Medical School to conduct cutting-edge research at the interface of immunology and virology. Specifically, the project will investigate the molecular mechanisms of how the innate immune system restricts the replication of polyomaviruses and other viral pathogens in various cell culture assays and mouse models.

Candidates should be accomplished in virology, molecular biology, biochemistry and/or immunology. Experience with DNA viruses, in particular polyomaviruses, and mouse infection studies would be especially desirable.

Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to:
Michaela Gack, Ph.D.
Department of Microbiology and Immunobiology
Harvard Medical School
Email: michaela_gack@hms.harvard.edu


Yang Laboratory at Harvard Medical School

The Yang Lab has two immediate openings for postdoctoral fellows to play a vital role in the discovery and optimization of small molecule antivirals. Must have established expertise in protein expression (microbial, insect, and mammalian cells) and purification as well as with a variety of biophysical and biochemical methods for characterizing protein-small molecule interactions. Experience with high-throughput screening and/or molecular virology techniques is desired but may be substituted with a willingness and aptitude to learn. Must be willing to work with viral pathogens in a BSL2+ lab.

You will be working within a multidisciplinary group of structural biologists, medicinal chemists, biochemists, and virologists. This position requires excellent communication and organizational skills, and a willingness to help train and mentor more junior members on the research team. This is an excellent opportunity for a post-doctoral fellow to acquire experience relevant to future employment in industry while still operating within an academic environment. This position is funded by an NIH grant through 2018. Applicants are expected to make a 3 year commitment.

Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to:
Priscilla L. Yang., Ph.D.
Department of Microbiology and Immunobiology
Harvard Medical School
Email: Priscilla_yang@hms.harvard.edu

 

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NEUROBIOLOGY

Gu Laboratory at Harvard Medical School
A postdoctoral position is available to study the coordinate development of nervous and vascular systems using mouse genetics, biochemistry, imaging, and in vitro assays. Applicants should be accomplished in biochemistry, molecular biology, cell biology. Experience in the biochemical and functional characterization of proteins in the signaling pathways would be especially desirable.

Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to:

Chenghua Gu, D.V.M., & Ph.D
Department of Neurobiology
Harvard Medical School
Email: chenghua_gu@hms.harvard.edu
HMS Dept. of Neurobiology Website: http://neuro.med.harvard.edu/


Weitz Laboratory at Harvard Medical School
A postdoctoral position is available to study protein complexes comprising the core of the mammalian circadian clock, a molecular oscillator present in multiple tissues that regulates physiology, metabolism, and behavior.  Applicants should be accomplished in biochemistry, molecular biology, and/or cell biology.  Experience in the biochemical and functional characterization of protein complexes would be especially desirable.

Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to:
Charles J. Weitz, M.D., Ph.D.
Department of Neurobiology
Harvard Medical School
Email:  cweitz@hms.harvard.edu
HMS Dept. of Neurobiology Website:  http://neuro.med.harvard.edu/

Some recent papers:
Duong HA, Robles MS, Knutti K, Weitz CJ.  A molecular mechanism for circadian clock negative feedback. Science  2011; 332: 1436-9.

Padmanabhan K, Robles MS, Westerling T, Weitz CJ.  Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex. Science  2012; 337:  599-602. 

Kim JY, Kwak PB, Weitz CJ.  Specificity in circadian clock feedback from targeted reconstitution of the NuRD co-repressor.  Molecular Cell  2014; 56: 738-748.

Tamayo AG, Duong HA, Robles MS, Mann M, Weitz CJ.  Histone mono-ubiquitination by Clock–Bmal1 complex marks Per1 and Per2 genes for circadian feedback. Nature Structural & Molecular Biology 2015; 22: 759-766.  


Goodrich Laboratory at Harvard Medical School

The Goodrich lab is seeking a postdoctoral fellow to study the development of neural circuits in the auditory system. We use mouse genetics to understand how changes in the circuits of the inner ear affect an animalís ability to detect and perceive sound. Projects employ a variety of techniques, including biochemical analysis of novel proteins, in vitro culturing of inner ear neurons, imaging of single cells during auditory circuit assembly, and gene expression profiling of wild-type and mutant cells. No experience with the auditory system is required, but a familiarity with neuroscience or mouse genetics is a plus. Individuals with expertise in cell biology, imaging, microarrays, or signal transduction are particularly encouraged to apply.

Please send a cover letter, CV, and three references to:

Dr. Lisa Goodrich
Dept of Neurobiology, Harvard Medical School
220 Longwood Avenue
Goldenson 442
Boston, MA 02115
Email: Lisa_Goodrich@hms.harvard.edu

 

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SYSTEMS BIOLOGY


Mootha Laboratory at Harvard Medical School
The Mootha laboratory (Department of Systems Biology) has a funded opportunity for a postdoctoral scientist in computational genetics.

The laboratory focuses on mitochondrial biology and disease and consists of a lively group of computational biologists, experimental biochemists, and physician-scientists. We are currently seeking a postdoctoral scientist to work at the interface of human genetics and systems biology, with the goal of analyzing very large scale human genome sequence datasets using network models of mitochondria derived from cellular and biochemical studies, to address questions spanning disease, epistasis, and evolution.

Applicants should possess a Ph.D. and/or M.D. degree in computational biology, preferably with a proven track record in computational genetics and analysis of next-generation sequencing data. Interested individuals should send a cover letter, curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to vamsi@hms.harvard.edu.

For additional information please visit our webpage: http://mootha.hms.harvard.edu/


Fontana Laboratory at Harvard Medical School
The Fontana Laboratory is seeking two outstanding post-docs to accomplish in collaboration with other groups a prototype end-to-end pipeline that extracts detailed mechanistic information about protein-protein interactions from databases and text, assembles such information into executable reference models for the purpose of understanding their dynamical behavior and assessing the current knowledge base in specific cell signaling systems. A can-do attitude, hacker soul, originality coupled to team spirit, fearlessness, and dedicated work ethic are necessary characteristics. Pay is commensurate to experience.

Position 1: Computer science / AI / bioinformatics / databases
The ideal candidate combines an interest, and possibly expertise, in Artificial Intelligence (text extraction, natural language processing, reasoning) with bioinformatic skills. The individual will collaborate with other groups in excavating information about molecular interactions from extant databases and text; organizing such information for translation into a formal and executable format from which models of cellular signaling are constructed. The candidate should be capable of scripting in Python or Perl, be familiar with procedural and functional programming paradigms (e.g. Java or similar and OCaml or similar) and have database experience.

Position 2: Modeler / cellular signaling / cancer pathways
The ideal candidate is a computational biologist with experience in modeling dynamical systems. The individual is a skilled programmer (C, C++ or similar, experience with OCaml a plus) who will work with Kappa, a formal agent-based modeling language (https://github.com/jkrivine/KaSim) and associated tools. Ease with formal / mathematical thinking is required. A sound instinct for molecular biology coupled to a physics mindset is highly desirable. The position functions as a modeling keystone within an ambitious project seeking to build large dynamic “reference models" of cell signaling networks involved in RAS-related cancers. Models of such networks are assembled using mechanistic knowledge extracted from databases and texts in collaboration with outside groups providing pertinent expertise.

To apply, send CV and a covering letter to Walter Fontana: walter@hms.harvard.edu.


Megason Laboratory at Harvard Medical School
A postdoctoral research fellow position is available in the Megason lab in the Department of Systems Biology at Harvard Medical School in the areas of embryology, genetics, imaging, and systems biology. The Megason Lab has initiated a project to generate a Digital Fish which is a computer recreation of how the genome is executed to turn an egg into an embryo. We combine novel imaging technologies called in toto imaging to extract quantitative molecular and cellular data from living, developing zebrafish embryos for use in modeling. In toto imaging uses confocal and 2-photon microscopy to image and track every cell in developmental processes to reconstruct complete digital cell lineages. We also are developing a novel genetic approach called FlipTraps which generate endogenously expressed fluorescent fusion proteins and Cre condtional alleles. We combine these approaches to generate quantitative models of how systems of molecules program cells and systems of cells program tissues. Additionally, we are particularly interested in applicants with experience, expertise, and interest in home built 2-photon microscopy systems. For more information please contact Sean Megason (megason@hms.harvard.edu) or visit our website www.digitalfish.org.

A cover letter detailing your research motivations and a curriculum vitae should be sent by email to the above address together with the names of three referees with contact information.

Sean Megason, PhD
Department of Systems Biology
Harvard Medical School
200 Longwood Avenue, WAB 536
Boston, MA 02115

 

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HARVARD SCHOOL OF DENTAL MEDICINE

 

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WYSS INSTITUTE


Postdoctoral Fellows Positions at the Wyss Institute for Biologically Inspired Engineering

The Wyss (pronounced "Veese") Institute for Biologically Inspired Engineering uses Nature's design principles to develop bioinspired materials and devices that will transform medicine and create a more sustainable world.

Working as an alliance among Harvard's Schools of Medicine, Engineering, and Arts & Sciences, and in partnership with Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Dana Farber Cancer Institute, Massachusetts General Hospital, the University of Massachusetts Medical School, Spaulding Rehabilitation Hospital, Tufts University, and Boston University, the Institute crosses disciplinary and institutional barriers to engage in high-risk research that leads to transformative technological breakthroughs.


Visit the Wyss Institute's website to find out positions available: http://wyss.harvard.edu/viewpage/191/postdoctoral-positions



Harvard Medical School | Gordon Hall of Medicine, Room 006 | 25 Shattuck Street | Boston, MA 02115 | postdoc_office@hms.harvard.edu
© 2009 by the President and Fellows of Harvard College