Open Postdoc Positions

Postdoctoral Positions at HMS Quad-based Labs

The Dean's Postdoctoral Fellowship | Curriculum Fellows ProgramBiological Chemistry and Molecular Pharmacology | Biomedical Informatics | Cell Biology | Center for Bioethics | Genetics | Global Health and Social Medicine | Harvard Catalyst | Health Care Policy | Microbiology and Immunobiology | Neurobiology | Systems Biology | Harvard School of Dental Medicine | Wyss Institute

This page lists some of the postdoctoral positions currently available on the HMS Quadrangle. Many principal investigators do not advertise their postdoctoral positions with us, so if the PI you want to work with isn't listed here, please contact her/him directly. Please do not send your CV to the administrator of this page.
For non-Quad or external positions please see:

Quad Departments: to have an opportunity listed on this page, send along a description of the postdoctoral position and contact information to us at

Postdoc openings at other Harvard affiliated institutions:
Beth Israel Deaconess Medical Center | Brigham & Women's Hospital | Children’s Hospital | Dana-Farber | Joslin | Mass General Hospital * | McLean Hospital* | T.H. Chan School of Public Health*
*Please note: some Harvard affiliates do not advertise individual postdoc positions with us, it may be best to identify a PI conducting work in your specific area of interest, and to email that PI directly with your CV and cover letter.


The Laboratory of Systems Pharmacology at Harvard Medical School

The Project Management Fellows Program provides postdoctoral fellows with a mix of hands-on and curriculum-based training in the facilitation of complex research in academic and industrial settings. Many NIH-funded research centers mandate or strongly encourage the inclusion of scientific managers and coordinators in research. This creates new career opportunities for skilled scientists interested in supporting the interdisciplinary, multi-investigator projects typical of contemporary biomedical science. The LPM program helps individuals take advantage of this opportunity by providing hands-on and curriculum-based training in facilitating complex research projects.

The Laboratory of Systems Pharmacology (LSP) at Harvard Medical School tackles difficult problems in translational biomedicine using systems pharmacology approaches that combine laboratory experiments, computer science and clinical studies. Within the LSP, experts in systems biology, basic and translational pharmacology, cell biology, infectious disease, clinical trials, and informatics work closely together to meet the goals of ambitious research programs funded by NIH center and program grants.
LSP projects involve collaboration among multiple faculty members, staff scientists and trainees with very different sets of skills and often based in different departments or institutions. These multi-investigator projects are facilitated by PhD-level scientific managers who help coordinate and integrate the different aspects of each large research project, including pipelines for managing diverse omic data, reagent verification, data curation and validation and communication with the larger scientific community. Scientific program managers play a key role in writing reports for funding agencies, coordination of scientific meetings and often contribute to scientific papers. The LSP scientific program managers will provide LPM fellows with guidance, peer support and mentorship through formal and informal mechanisms.

The Project Management Fellows Program
LPM Fellows will have the opportunity to acquire and refine the required for the effective coordination of large collaborative projects, and obtain Project Management Professional (PMP) certification, a designation required or strongly preferred by employers in industry and government.
Each LPM Fellow will gain hands-on experience in the coordination of multiple research projects and learn the basics of grant management by supporting an NIH Center or Program Project research team within LSP. Fellows will also engage in a rigorous professional development program that draws directly on and supports their project management role in the LSP. Fellows will complete the MassBio Project Management for Biotech course (8 evenings), LSP-based skills assessment and communication workshops, and will be expected to enroll in other short courses at Harvard University specific to their own interests (e.g. “Research administration of sponsored awards”, “Difficult conversations”, “Introduction to management in research”, “Managing up”). The Fellow will independently prepare for the Project Management Exam using the Lynda preparatory courses and other resources.  All expenses related to training and examination will be covered.
A successful LPM Fellow will, within a 2-3 year training period:
-Demonstrate their ability to facilitate complex research projects,
-Hone written and verbal communication skills,
-Develop a working relationship with funding agencies,
-Engage a network of peers and mentors regionally,
-Become certified as a Project Management Professional.

The skills the Fellows will acquire can provide opportunities for several career paths, including:
-Managing a research program, center or other similar activity in academia, in partnership with a faculty leader.
-Project management for biotech or pharmaceutical industry laboratories.
-Research administration in academe, government or industry
-Program management in a federal agency such as NIH or NSF.

The LINCS LPM Fellowship
The LSP is recruiting a LPM Fellow in support of the NIH Library of Integrated Network-based Cellular Signatures (LINCS)Center based in the LSP ( The HMS LINCS Center was established in October 2010 to develop experimental and computational strategies to identify cell “signatures” that describe how cells respond to different chemical or biological perturbations. As of March 2017, seven centers across the U.S. participate in the NIH LINCS consortium program. The HMS LINCS Center is identifying signatures that measure the responses of cells derived from different human tissues to therapeutic drugs. Much of the work focuses on cultured cells (from breast, liver and colon), but the Center also studies primary human cells from normal and diseased patients.  As perturbing agents, the focus is on small molecule kinase inhibitors, which are a leading class of therapeutic agents for treatment of cancer, autoimmune and other diseases.
In their research management role, the fellow will collaborate with HMS LINCS investigators to:
-Play a prominent role within the HMS LINCS group curating and organizing experimental data.
-Develop and execute plans for LINCS data releases to public repositories.
-Help to coordinate HMS LINCS data production, data annotation and outreach activities with the work of other LINCS centers.
-Participate in LINCS consortium activities, including regular calls for the Steering Committee, Data Working Group, and Experimental Working Group, and in-person meetings.
-Communicate with the NIH program office regarding required reports, data releases, outreach activities and metrics collection.
-Attend and participate in LSP and Sorger lab group meetings and in the regular and ad hoc meetings involving LINCS PIs, postdocs, students and staff
The Fellow will be appointed as a postdoctoral fellow under LINCS PI and LSP Director Peter Sorger, work on a day-to-day basis with postdocs and staff active in LINCS and receive mentorship and guidance from LSP Scientific Managers and Executive Director.  This position will have a high degree of independence, and opportunities to present at regional and national scientific symposia and workshops.

-PhD in cell biology, biochemistry, molecular biology, pharmacology, systems biology, chemical biology, biophysics or related field
-Demonstrated experience or a strong statement of interest in collaborative research
-Excellent written and verbal communication skills
-Strong organizational and interpersonal skills
-Interest in research coordination and project management

Applications should provide a CV, cover letter and 3 letters of recommendation via email to

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The Dean's Postdoctoral Fellowship

Co-Sponsored by: The Office for Diversity Inclusion and Community Partnership and The Office for Postdoctoral Fellows

As part of an effort to promote a diversity of backgrounds, perspectives, and experiences among its faculty and trainees, Harvard Medical School invites applications for the Dean’s Postdoctoral Fellowship.
The Office for Diversity Inclusion and Community Partnership in collaboration with The Office for Postdoctoral Fellows will award two-year postdoctoral fellowships per year to two promising researchers in the fields of basic or social sciences. The Dean’s Postdoctoral Fellowship at Harvard Medical School will prepare postdoctoral scientists, particularly scientists from minority and disadvantaged backgrounds, for cutting-edge research careers.  This fellowship will position the right candidate to make major contributions as scientific and societal leaders.
Fellows will benefit from a highly innovative and creative research environment that emphasizes scientific rigor, collaboration, and the pursuit of excellence in science.  In addition, Fellows are welcome to join the HMS the Society for Translational and Academic Researchers (STARs), sponsored by the Office for Diversity Inclusion and Community Partnership
For more info or to apply:

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The Harvard Medical School Curriculum Fellows Program (CFP)
2 positions listed (1.16.18)

The CFP is seeking a post-doctoral Curriculum Fellow (CF) who will provide teaching curriculum, student oversight, education research, and administrative management support for the Harvard/MIT MD-PhD Program at Harvard Medical School.  Our overall mission is to train the next generation of premier physician-scientists, with representation across a rich diversity of clinical disciplines and research areas from basic and translational sciences to bioengineering to the social sciences.  We serve over 175 students at various stages of training across two medical school curricula, 5 medical school advising societies, 3 clinical clerkship hospitals, and over 25 different PhD programs across Harvard and MIT. 
The MD-PhD CF will work directly with the MD-PhD Program Director and interact with program faculty, students, and staff to maximize the education, training, operations, and education research activities of the program, including: 
-Develop, implement, and support academic and para-curricular activities that enhance the rigorous training and dynamic community of physician-scientists at Harvard and MIT 
-Evaluate the effectiveness of existing academic and para-curricular MD-PhD activities and establish a systematic approach to the collection and analysis of data to assess student and alumni outcomes
-Support MD-PhD program and school-wide student training and alumni engagement initiatives
-Collaborate on the advancement of MD-PhD education research studies, including academic publication and presentation.
-An earned M.D. or Ph.D. in biomedical sciences
-Institutional experience in medical and graduate education practices
-Postdoctoral research or teaching experience (preferred)
 Job Skills and Competencies:
-Outstanding writing, oral, and organizational skills
-Project or program management skills
-Motivated, independent, and creative
-Collaborative in a team setting
-Excellent social skills
-Experience working with students, faculty, and administrators
The MD-PhD Curriculum Fellow is a member of the HMS Curriculum Fellows Program, a science education community that functions as a training program for early career scientist teachers while also contributing to the development and oversight of high quality, innovative graduate education at Harvard. Pedagogical training is incorporated into the fellow’s course- and program-based efforts and includes opportunities to design and conduct educational research projects. CFs receive mentorship and career advising to support their development as educators throughout the duration of the appointment. The MD-PhD Curriculum Fellow position is particularly well suited for someone with Higher Education Administration career aspirations.
To apply: 
To be considered for this position, please email a single pdf document containing a letter of application that addresses your interest in and qualifications for the position, a curriculum vitae, and a statement of teaching philosophy.  Please include the names and contact information of three references, who will be asked to supply letters or will be contacted by phone early in the application screening process. The CF position and its associated academic appointment is a one year appointment, renewable for three years, and is non tenure-track. Applications will be reviewed on a rolling basis, starting immediately. The ideal start date for the position is summer 2018 or earlier at Harvard Medical School in Boston. 
Address applications to: 
Bradley Coleman, Ph.D. 
Co-Director, Curriculum Fellows Program 
Via Ms. Naima Abdullahi (
Harvard University is an equal opportunity employer.
Harvard/MIT MD-PhD Program: 
Curriculum Fellows Program  


Curriculum Fellow in Quantitative Biomedical Training
Seeking a CF to develop and support the quantitative curriculum of PhD students in the various biomedical graduate programs at HMS.
As our students are increasingly required to understand and apply statistical and quantitative analyses, we must continue to expand our curricula to provide them with the training and hands-on experiences that will support the development of this expertise. The Quantitative Curriculum Fellow will work with faculty and fellows across HMS to identify and improve existing opportunities for quantitative training while also designing and implementing new courses, programs and workshops to fill perceived training gaps.
-Work closely with the faculty director of a current introductory course -in quantitative approaches to develop and administer lectures, workshops, online instructional materials and assessments.
-Provide academic support to faculty teaching other quantitative courses.
-Provide expertise and advice to faculty and fellows as they incorporate quantitative and statistical content into existing basic science courses.
-Work directly with students to support their learning of quantitative content.
-An earned doctorate in a relevant field (e.g., biology, computational biology, computer science, biomedical informatics, etc.)
-Experience teaching graduate or undergraduate students
-Postdoctoral qualifications: research and/or teaching experience (preferred)
Job Skills and Competencies
-Demonstrated quantitative expertise and experience with biomedical data
-Demonstrated expertise in the application of statistical analyses to biomedical data
-Proficiency with R (preferred) and/or Python, MATLAB or other languages
-Ability to work collaboratively with multiple faculty and administrative partners to develop new courses and educational/training opportunities
-Experience applying pedagogical best practices to the classroom, including evidence-based teaching methods and technological innovations
-Strong oral and written communication skills, strict attention to detail
-Strong organizational and administrative skills and the ability to successfully plan and implement programs and events
-Ability to work independently to identify and implement optimal solutions to diverse problems
-Effective mentorship skills
The Curriculum Fellow position is well suited to an academically-minded scientist who is passionate about graduate biomedical education and sees this fellowship as an opportunity to both hone their pedagogical skills and influence the training outcomes of Harvard Medical School’s PhD students. The Quantitative Curriculum Fellow will be a member of the HMS Curriculum Fellows Program, a science education community that functions as a training program for early career scientist-teachers. Pedagogical training is incorporated into the fellow’s course- and program-based efforts and includes opportunities to design and conduct discipline-based educational research (DBER) projects. Curriculum Fellows receive mentorship and career advising to support their development as educators throughout the duration of the appointment.
To apply
To be considered for this position, please email a single PDF document containing (1) a letter of application that addresses your interest in and qualifications for the position, (2) a curriculum vitae, and (3) a statement of teaching philosophy. Please include the names and contact information of three references, who will be asked to supply letters or will be contacted by phone early in the application screening process. The CF position and its associated academic appointment is a one-year appointment, renewable for three years, and is non-tenure-track. Fellows are hired at the rank of research associate or Lecturer, commensurate with experience. Applications will be reviewed on a rolling basis, starting immediately. The expected start date for this position is spring 2018 in Boston, MA.
For details about the Curriculum Fellows Program, please see
Address applications to:
Bradley Coleman, Ph.D.
Co-Director, Curriculum Fellows Program
via Ms. Naima Abdullahi (
Harvard University is an equal opportunity employer.



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The Arthanari Lab
The Arthanari Lab at Department of BCMP, Harvard Medical School and Department of Cancer Biology, Dana Farber Cancer Institute is seeking a highly motivated postdoctoral candidate with expertise in transcriptional biology. Our laboratory works at the interface of structural biology, drug discovery and mechanistic biology, focusing on transcription factors and their interactions with co-activators and mediators (e.g. Nature 2016 25;530 (7591): 485-9; Nature 2008 452 (7187): 604-9). Research efforts will be focused on the intersection of cancer biology/genetics and immune-oncology. The candidate is expected to have a comprehensive understanding of signaling pathways, epigenetics and transcription regulation. Experience in technical skills including cell culture, somatic genetic analysis (e.g., CRISPr, si-, sh- RNA knockdown and rescue), protein biochemistry, assay design and development and biological applications to advance discovery are preferred. The individual should be independent and passionate about science and have an established record of creativity, ability to work in teams and strong publication record in peer-reviewed scientific journals.
Interested applicants should send a CV, and the names/phone numbers of three references by email to

Blacklow Laboratory at Harvard Medical School
The Blacklow Laboratory at Harvard Medical School (Department of Biological Chemistry and Molecular Pharmacology) has an opening for a Postdoctoral position. The laboratory currently investigates structure-function relationships in Notch signaling, its downstream targets, and its epigenetic regulators.
Applicants should possess a Ph.D. and/or M.D. degree in Molecular Biology, Cell Biology, Biochemistry, Structural Biology or a related field.
Interested individuals should send a cover letter, curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to

The Brown Laboratory
Postdoctoral Fellow in Electron Cryomicroscopy (Full posting:
Position Description: A postdoctoral position is available in the Brown lab at Harvard Medical School. The lab uses the latest developments in cryo-EM to understand biological processes at the molecular level (e.g. Nature 524, 493–496 and Science 346, 718–722). The project will involve investigating the structure and function of large macromolecular complexes involved in cellular transport. This includes all steps from construct design to structure determination. In the long term, we aim to use detailed molecular models to facilitate the development of new and better therapeutics.
Job requirements: Applicants should hold (or will be shortly awarded) a PhD degree and have experience in molecular biology and protein purification. Prior experience with single-particle cryo-EM or X-ray crystallography is considered a major advantage. Candidates should have strong communication skills and an established record of creativity through principal authorship in peer-reviewed publication(s). The successful candidate should be passionate about science, motivated, proactive, and able to work in a team. While each lab member has their own project, lab members are encouraged to work together to solve common problems. A separate position is available for an outstanding candidate with expertise in electron cryotomography (cryo-ET).
The position is initially for 2 years with a possibility of extension.
If you’re interested in joining the lab, please send your CV with a brief description of your current research as well as 2-3 contacts for references to before the 8th August, 2017.

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Avillach Laboratory at Harvard Medical School

Research Fellow Position at the Department of Biomedical Informatics (posted 10/16/15)

Description: The Department of Biomedical Informatics (DBMI) at Harvard Medical School is looking for a Research Fellow to help us build cutting edge research platforms. We seek an individual to work on our multidisciplinary team of data scientists, medical doctors, and developers. Our team studies large and disparate datasets from the domains of biology, healthcare and social media. The goal of our efforts is to transform healthcare and research to usher in a new age of individualized data driven medicine.
The Research Fellow will be responsible for developing novel methodologies and applications to help visual causal relationships in bioinformatics data sets. The diversity of subject matter will require a creative mind and a candidate capable of deploying imaginative strategies and who is dedicated to solving complex and challenging problems within an interdisciplinary environment.
Specific responsibilities for this position include:
• Work to understand data about causal relationships in order to develop visualizations.
• Create prototypes for visualizations and work with software professionals to integrate the work into an existing platform.
• Perform novel research on bioinformatics data sets and publish any findings.

For details and additional information:

Gehlenborg Laboratory at Harvard Medical School

Multiple postdoctoral fellowships are available immediately in the Gehlenborg Lab in the Department of Biomedical Informatics at Harvard Medical School. (posted 10/21/15)

The goal of the lab is to improve human health by developing computational techniques and interfaces that enable biomedical and clinical investigators to efficiently interact with biomedical data. We design, implement and evaluate methods and tools that leverage the knowledge and cognitive skills of investigators in order to enable the interpretation of massive heterogeneous data sets that integrate genomic and clinical data. Please see for additional information about our work.

Possible research projects include development of data visualization, analysis, and management tools to study genomic structural variants, dynamics of the 3D genome, and cancer subtypes in patient cohorts. Further projects involve the design and implementation of visual exploration tools for biomedical data repositories and tools for viewing and interacting with provenance graphs. All of the projects are highly interdisciplinary and are being conducted in close cooperation with computational or experimental domain experts providing an excellent opportunity for collaborative research.

Our lab in the Department of Biomedical Informatics is part of a vibrant community of scientists, physicians, and engineers whose goal is to advance the boundaries of knowledge. The Department has recently been formed at Harvard Medical School to lead development of computational and informatics techniques to address pertinent challenges in modern biological sciences and medicine. The Department’s faculty conduct research at the intersection of biomedicine and information sciences, including bioinformatics, functional genomics, translational medicine, and clinical knowledge management. Based on the Harvard Medical School Longwood Campus, it provides a rich scientific environment, with many seminar series and invited speakers of the highest caliber.

For details and additional information:

Kharchenko Laboratory at Harvard Medical School

A laboratory at the newly-formed Department of Biomedical Informatics at the Harvard Medical School (HMS) is looking to recruit several postdoctoral fellows interested in pursuing one or more of the following topics in computational biology:
I. Single-Cell Genomics
II. Computational analysis of epigenetic mechanisms disrupted in cancer and other disease-disrupted tissues
III. Computational analysis of nucleosome organization
(posted on 2/4/16)

For details and additional information:


Patel Laboratory at Harvard Medical School

The Patel Group in the Harvard Medical School Department of Biomedical Informatics ( is looking for a Post-Doctoral research fellow to run a collaborative study with Northeastern University’s Antimicrobial Discovery Center that will uncover the characteristics of Lyme disease around the US leveraging emerging large and high-dimensional clinical data streams. Candidates must have a PhD in computer science, mathematics, physics, biomedical informatics, bioinformatics, or a related quantitative field. Preferred qualifications for this position include experience designing large software applications and infrastructure to store, retrieve, and analyze large datasets. Industry experience with R, Python, SQL is required. Experience in hacking with cloud technologies is great. Email applications including curriculum vitae, summary statement of personal objectives, and the names and email addresses of 2-3 references to Chirag Patel ( Harvard Medical School is an Equal Opportunity/Affirmative Action Employer. Women and minorities are especially encouraged to apply. (posted 3/2/16)

Biomedical Data Scientist Postdoctoral Associate (posted 2/4/16)
Imagine a dynamic dataset that encompasses comprehensive information about a patient in the health care system: what diseases they have, their genomic sequence, their social media messages (e.g, tweets and likes), and where they live. How would you—a data hacker—store, retrieve, and analyze this information to drive biomedical discovery to find a new way of predicting disease or even a new therapy for a disease? Chirag Patel’s Group at the Department of Biomedical Informatics at Harvard Medical School is looking for a data engineer to build cutting-edge platforms and data infrastructure to enable large-scale data-driven research to address this question. We aim to integrate diverse data sources from geotemporal information (e.g., NOAA Weather Data, EPA AirData), individual genomic sequence, social media data, and health claims information to paint a comprehensive picture of individuals who are sick and healthy.

For details and additional information:

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Yuan Laboratory at Harvard Medical School
The Yuan laboratory at Harvard Medical School (Department of Cell Biology) has an immediate opening for a postdoctoral scientist. Our laboratory investigates the molecular mechanisms of cell death, including necroptosis and apoptosis, and their relevance for human diseases. This position is for a highly motivated individual with considerable experience in cell biology or related field. Experience in animal models of human diseases is desirable but not required.

Applicants should possess a Ph.D. and/or M.D. degree in molecular biology, cell biology, biochemistry, or neurobiology and a strong publication record. Interested individuals should send a curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to

For additional information please visit our webpage:

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The Harvard Medical School Center for Bioethics invites applications for the Postdoctoral Research Scholars Program in Bioethics, for appointments commencing in summer/fall 2018.

This 1-2 year program prepares scholars with the knowledge and skills necessary to become leaders in the field of bioethics. Research scholars are fully integrated into the community of faculty and students at the Center for Bioethics, with access to the resources of Harvard Medical School and Harvard University. The program includes opportunities to collaborate with the scholars at the Hastings Center. We are particularly focused on attracting candidates with an interest in working on ethical and policy issues in regenerative and synthetic biology, genetic engineering, stem cell biology and embryology. Ideal candidates would be promising scientists in these areas with a background in bioethics or with a serious commitment to gaining expertise in the field
Research scholars will receive an annual stipend, benefits, and an allotment for academic expenses and travel.

The core experience includes:

  • Mentored research. Research scholars work closely with faculty mentors from across Harvard University to develop and conduct original research in the field of bioethics. A primary aim of the program is to prepare candidates with the training necessary to obtain competitive research funding and develop a successful academic career in bioethics.
  • Educational opportunities. The program seeks candidates with diverse backgrounds, experience, and knowledge. Each scholar works with faculty creating a personalized educational program that will delve into special areas of interest, as well as developing broad expertise in the field of bioethics. Research scholars have access to all the Center's courses and seminars, and may be able to audit relevant courses across Harvard University with faculty permission.
  • Community life. Postdoctoral research scholars will be fully engaged with the activities of the Center and the Harvard-affiliated teaching hospitals. Scholars will organize and conduct conferences and seminars, they will assist in teaching courses in their areas of interest, and will have opportunities to participate on hospital clinical ethics committees and institutional review boards.

In short, the Postdoctoral Research Scholars Program provides the greatest possible access to all that Harvard University has to offer.

Application Requirements:
Applications are invited from those who have or will have completed a doctoral degree (MD, JD, PhD or equivalent) by July 1, 2018. Doctorates may be in any relevant field, including but not limited to public health, psychology, economics, philosophy, sociology, or anthropology.
The deadline for summer/fall 2018 is March 30, 2018. Applications may be considered throughout the year under special circumstances.
Visit the website for application requirements:

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Sinclair Laboratory at Harvard Medical School
Computational Biology/Bioinformatics Post-doctoral position available immediately (posted 12.1.17)
We are seeking a talented, highly motivated individual to join the laboratory headed by Professor David Sinclair in the Genetics Department at Harvard Medical School, Boston. The Sinclair lab is known for their work on genes and small molecules that delay aging and treat age-related diseases. The lab has a wide range or expertise and interests, including cancer, neurodegeneration, diabetes, and fertility. The laboratory has a record of innovation with over 40 patents and numerous start-up companies. In 2014, Dr. Sinclair was on the TIME100 list of the “most influential people in the world.” This is also an opportunity to innovate and be involved in the foundation of one or more new companies.
We are seeking a talented individual with a background in computational science or bioinformatics. The position offers an opportunity to work with an engaged group of scientists and participate in cutting edge research combining proteomics and genomics. The ideal candidate will have experience working on Linux-type servers and with programming languages (e.g. C/C++, Python, Perl, R, HTML, Java etc.). The position requires expertise in genomics, transcriptomics and/or proteomics data analysis. The candidate will work on integrative and translational analysis of multiple levels of omics data. The focus will be on applying systems-omics methods to biological research questions and to analyze the acquired data. This includes both the use of established methods of data analysis and identification and testing of new strategies and solutions for the analysis of quantitative biological data. The individual will also participate in the development of our proteo-genomics analysis pipeline.
Principal Responsibilities:

  • Lead in the development of new methods and algorithms/pipelines to analyze next-generation sequence of genomes, epigenomes, and transcriptomes derived from experimental specimens.
  • Lead in the development of computational tools and resources/databases to integrate genomics and functional genomics datasets.
  • Identification of regulatory networks through integration of multiple layers of data, including but not limited to genome sequences, gene and small RNA expression profiles, metabolite profiles, and DNA methylation profile.
  • Implement new analytical tools capable of troubleshooting and accelerating the data analysis.
  • Work with the molecular biology team to develop protocols that enable parallel interpretation of sequencing and proteomics data.
  • Process, analyze and interpret high volumes of data as part of wide range of internal and external scientific studies. Apply automated methods and software to support large-scale bioinformatics analysis.
  • Provide bioinformatics resources for day-to-day use by members of the laboratory.
  • Monitor and evaluate analytical aspects of new and emerging technologies (sequencing proteomics and others).
  • Present scientific and technical data to both internal and external scientific colleagues in a clear and cohesive manner.
  • Work independently and prepare timetables, deliverables, and project schedules.
    Required Skills/Abilities/Competencies:
  • Ph.D. in Bioinformatics, Computational Biology, Computer Science or related fields.
  • Experience with and deep understanding of algorithms, data structures, and scientific programming for analysis of biological data.
  • Proven understanding and experience in the fields of genomics, data processing, high-throughput data analysis, and genomic databases
  • Must have experience with sequence data formats and processing from Next Generation platforms (Illumina, PacBio, etc.)
  • Software engineering skills with proficiency in: Java, C++  Perl, Python and R
  • Excellent track record of analyzing next generation sequencing data, particularly WGS, HiC-seq, ChIP-seq, and RNA-seq.
  • Experience in a Unix/Linux environment.
  • Experience with common tools for
    o NGS (BWA, GATK, STAR, Samtools, Picard, TopHat, Cufflinks, etc.)
    o ChiP-seq; HiC-seq (Bowtie, MACS, SICER, HOMER, etc.)
    o Proteomics (mzR, mzLD, etc.)
    o Metabolomics (metaboAnalyst, etc.)
    o De novo assembly (e.g. SOAPdenovo, Velvet, Abyss, and ALLPATHS-LG)
    o Genome annotation (e.g. Augustus, MAKER)
  • Experience in algorithm development for analysis of massively parallel sequencing data (NGS outputs of ChiP-seq, ATAC-seq, bulk cell and single cell RNA-seq, and whole genome sequencing).
  • Experience with statistical analysis is strongly preferred.
  • Strong scientific understanding of molecular and cellular biology, genetics and genomics.
  • Candidates must demonstrate outstanding personal initiative.
  • Excellent teamwork, time management and organizational skills.
  • Ability to work independently in a multidisciplinary, fast-paced, dynamic and results-oriented environment.
  • Ability to present data to a multidisciplinary audience in a clear and cohesive manner.Ability to meet deadlines and multitask efficiently is a must.

The ideal candidate will have a record of scientific rigor and creativity, a strong publication record in peer-reviewed scientific journals and the ability to work in teams. Candidates should have a strong background in genomics, proteomics and metabolomics. Excellent oral and written communication skills are required. The individual will present regular updates to academic and industry collaborators as well as prepare and publish research reports. There is a real opportunity to invent and to innovate.
To apply, send cover letter and CV to

Yankner Laboratory at Harvard Medical School
Positions available to study gene regulation, epigenetics and the molecular biology of aging and neurodegenerative diseases.  Projects focus on iPS cells, C. elegans, animal models and the biology of genes involved in aging and Alzheimer's disease. For reference see: Nature 507:448, 2014, J. Cell Biol. 203:457, 2013, Mol. Cell 40:333, 2010, Nature 464:529, 2010, Nature 429:883, 2004. Experience in molecular biology is required.

Send CV, a brief description of research experience and names of 3 references to: Dr. Bruce Yankner by email to

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Research Fellowship

The Department of Global Health and Social Medicine seeks a postdoctoral fellow to support the design and evaluation of large-scale intervention programs forming part of the core research and teaching activities of the Harvard Medical School Center for Global Health Delivery-Dubai. The Center has three concurrent missions: (1) to conduct and publish cutting edge health delivery research on innovative approaches to addressing health problems of critical importance to the region and world; (2) to train the next generation of scholars and practitioners from Dubai and the region in global health delivery; and (3) to enable Dubai to serve as an important regional hub for discussions and policy formulation on health problems of critical importance to Dubai, the United Arab Emirates, the region, and the world. This position is employed by a Dubai-based affiliate of Harvard Global Research and Support Services Inc. (Harvard Global). Harvard Global is itself a wholly controlled affiliate of Harvard University.

The successful candidate would have epidemiological and biostatistical background, and experience in designing studies and analytic plans, data analysis and interpretation, report and manuscript writing.  The fellowship is funded by the Center to train postdoctoral candidates for a successful research career as an epidemiologist/biostatistician focused on global health delivery. The minimal required qualification is a doctoral degree (PhD, DRPH, ScD or equivalent) in epidemiology, biostatistics, public health or related discipline. The position will be based in Dubai and will be offered for one year (renewable for one additional year based on performance).  The ideal candidate will have finished their doctoral studies within five years of the date of application.  Knowledge of Arabic is an asset but not required.  

Applicants must send a cover letter stating their long-term career aims and suitability for the position, curriculum vitae, statement of teaching interests, statement of research plans, and names and contact information for at least three potential references. Email applications to The position is scheduled to start on October 1, 2017. Applications will be accepted until the position is filled.

Candidates should be eligible for employment sponsorship in Dubai, United Arab Emirates. Offers are conditional on proper work authorization. A signed employment agreement will be issued by Harvard Global’s affiliate and may include a pre-employment background and reference checks. Harvard Global and its affiliates are equal opportunity employers and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Start date: October 1, 2017
Location: Dubai, United Arab Emirates
For additional information, see: HMS Center for Global Health Delivery—Dubai

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Post-doctoral Research Fellow – The Football Players Health Study

The Football Players Health Study at Harvard University aims to evaluate and improve the health and wellbeing of former professional football players. The Study is funded by the NFL Players Association (NFLPA) and is one of the largest sports research projects ever undertaken.  The Study is researching the prevalence and severity of medical conditions that affect the quality and longevity of life of football players and working to identify and prioritize promising new approaches to prevent, diagnose and treat those conditions that afflict them. The Study strives to meet its aims by collecting data directly from players, by supporting innovative research through pilot awards, and by investigating ethical considerations of players’ conditions. The research program sits within Harvard Catalyst | The Harvard Clinical and Translational Science Center. Harvard Catalyst facilitates clinical and translational research throughout the 27 Harvard schools and Academic Healthcare Centers (Massachusetts General Hospital, Boston Children's Hospital, Beth Israel Deaconess Medical Center, Brigham and Women's Hospital, Dana-Farber Cancer Institute, and others) by educating and training investigators, providing tools and technologies that enable their research, and bringing diverse communities together to accelerate the pace of investigation.

The Football Players Health Study at Harvard University is seeking a highly motivated post-doctoral research fellow (PhD, MD or MD/PhD) who will help to further study design, write IRB protocols, and conduct data analysis under the guidance and direction of our lead investigators.  Additional responsibilities include coordinating with the IRB, presenting work at local and national meetings, and writing scientific manuscripts.  The position will be co-mentored by Drs. Alvaro Pascual-Leone and William Meehan.  This is a one- year position with the option to renew annually.

Applicants must have a doctoral degree (PhD, MD or MD/PhD) in a relevant area; including any medical specialty or scientific field with a dedicated interest in the care of athletes.  Ability to handle confidential and sensitive information discreetly is required.

Other preferred requirements include:
-- Ability to design and conduct data analysis for cross-sectional and longitudinal studies.
-- Proven ability and experience in a subset of SAS, SPSS or related statistical packages.
-- Excellent oral and written skills.
-- Speak fluently in English.

Please submit letter of interest, CV, one copy of any relevant publication, and names/addresses of three references to Dr. Supriya Krishnan (

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Abraham Laboratory at Harvard Medical School
The Abraham Lab in the Department of Microbiology and Immunobiology at Harvard Medical School is seeking a highly motivated postdoctoral candidate with expertise in molecular biology and protein biochemistry. Our laboratory uses methods in structural biology, human immunology, and virology, to study on how emerging pathogens interact with host cells and are neutralized by antibodies (e.g. Cell Host & Microbe 18, 705–713, 2015).
Interested applicants should send a CV, including the names/email addresses of three references, to

Gack Laboratory at Harvard Medical School
Two postdoctoral positions are available immediately in the laboratory of Dr. Michaela Gack at the Department of Microbiology and Immunobiology of Harvard Medical School to conduct cutting-edge research at the interface of immunology and virology. Specifically, the project will investigate the molecular mechanisms of how the innate immune system restricts the replication of polyomaviruses and other viral pathogens in various cell culture assays and mouse models.

Candidates should be accomplished in virology, molecular biology, biochemistry and/or immunology. Experience with DNA viruses, in particular polyomaviruses, and mouse infection studies would be especially desirable.

Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to:
Michaela Gack, Ph.D.
Department of Microbiology and Immunobiology
Harvard Medical School


Gehrke Laboratory at Harvard Medical School
The Gehrke laboratory is looking for a U.S. citizen postdoc to join a team that is studying neurotropic virus infections using 2D and 3D tissue models.  Applicants must have Ph.D. or M.D. degree with a background in virology and familiarity with molecular techniques.  The work will involve BSL3 pathogens. Available immediately. Please send inquiries to (6.2.17)

Yang Laboratory at Harvard Medical School
The Yang Lab has two immediate openings for postdoctoral fellows to play a vital role in the discovery and optimization of small molecule antivirals. Must have established expertise in protein expression (microbial, insect, and mammalian cells) and purification as well as with a variety of biophysical and biochemical methods for characterizing protein-small molecule interactions. Experience with high-throughput screening and/or molecular virology techniques is desired but may be substituted with a willingness and aptitude to learn. Must be willing to work with viral pathogens in a BSL2+ lab.

You will be working within a multidisciplinary group of structural biologists, medicinal chemists, biochemists, and virologists. This position requires excellent communication and organizational skills, and a willingness to help train and mentor more junior members on the research team. This is an excellent opportunity for a post-doctoral fellow to acquire experience relevant to future employment in industry while still operating within an academic environment. This position is funded by an NIH grant through 2018. Applicants are expected to make a 3 year commitment.

Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to:
Priscilla L. Yang., Ph.D.
Department of Microbiology and Immunobiology
Harvard Medical School

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Gu Laboratory at Harvard Medical School
A postdoctoral position is available to study the coordinate development of nervous and vascular systems using mouse genetics, biochemistry, imaging, and in vitro assays. Applicants should be accomplished in biochemistry, molecular biology, cell biology. Experience in the biochemical and functional characterization of proteins in the signaling pathways would be especially desirable.
 Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to:
 Chenghua Gu, D.V.M., & Ph.D
Department of Neurobiology
Harvard Medical School
HMS Dept. of Neurobiology Website:

Kaeser Lab at Harvard Medical School
The Kaeser lab in the Department of Neurobiology at Harvard Medical School is seeking postdoctoral fellows to study architecture, functions and diversity of presynaptic neurotransmitter release sites. We are deeply invested into dissecting the molecular machines called active zones that mediate the release of fast neurotransmitters, for example glutamate, and of neuromodulators, for example dopamine. We further study how active zone composition is modulated by activity and how cell-type or synapse specific active zone architecture modulates circuit function. We use a variety of techniques (mouse genetics, protein biochemistry, electrophysiology, optogenetics, functional imaging, superresolution and electron microscopy) to study how active zones assemble and operate. Training in neuroscience and experience in any of these techniques is desirable, but not mandatory. We offer an excellent environment to use a multidisciplinary approach for addressing fundamental secretory mechanisms in a collaborative atmosphere.
Please email a cover letter, a curriculum vitae, and names & email addresses of three references to:
Dr. Pascal Kaeser
Department of Neurobiology
Harvard Medical School
220 Longwood Ave.
Armenise 305
Boston, MA 02115


Pecot Lab at Harvard Medical School
The Pecot Lab in the Department of Neurobiology at Harvard Medical School is seeking postdoctoral researchers interested in studying the molecular basis of precise neural connectivity. The goal of our research is to identify general molecular and cellular principles that underlie how neural networks are assembled. We address this at the level of identified cell types and synapses in the fly visual system. We are interested in the molecules that underlie how neurons distinguish each other and form synapses with appropriate partners, and in determining the gene regulatory networks that give rise to the expression of these genes in specific cell types. We employ a diverse experimental approach, involving molecular genetics, transcriptome profiling, genomics, confocal and superresolution microscopy, calcium imaging, and electron microscopy. Training in neuroscience or fly genetics is welcome but not necessary. We offer a supportive, collaborative and creative environment. 
Please email a cover letter, a curriculum vitae, and names & email addresses of three references to:
Matthew Y. Pecot, Ph.D.
Department of Neurobiology
Harvard Medical School
Armenise 203
Boston, MA 02115

Weitz Laboratory at Harvard Medical School
A postdoctoral position is available for cryo-EM analysis of protein complexes comprising the core of the mammalian circadian clock, a molecular oscillator present in all or nearly all cells that drives daily rhythms of physiology and behavior. Applicants should be accomplished in biochemistry and structural biology. Expertise in cryo-EM structure determination would be especially desirable. We have made progress in single-particle analysis of native circadian clock complexes purified from mouse tissues, and we aim to obtain high-resolution structures.
Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to:
Charles J. Weitz, M.D., Ph.D.
Department of Neurobiology
Harvard Medical School

Some recent papers:
1. Duong HA, Robles MS, Knutti K, Weitz CJ. A molecular mechanism for circadian clock negative feedback. Science 2011; 332: 1436-9.
2. Padmanabhan K, Robles MS, Westerling T, Weitz CJ. Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex. Science 2012; 337: 599-602.
3. Kim JY, Kwak PB, Weitz CJ. Specificity in circadian clock feedback from targeted reconstitution of the NuRD co-repressor. Molecular Cell 2014; 56: 738-748.
4. Tamayo AG, Duong HA, Robles MS, Mann M, Weitz CJ. Histone mono-ubiquitination by Clock–Bmal1 complex marks Per1 and Per2 genes for circadian feedback. Nature Structural & Molecular Biology 2015; 22: 759-766.
5. Aryal RP, Kwak PB, Tamayo AG, Chiu PL, Walz T, Weitz CJ. Macromolecular assemblies of the mammalian circadian clock. Molecular Cell 2017 (in press).

Goodrich Laboratory at Harvard Medical School
The Goodrich lab is seeking a postdoctoral fellow to study the development of neural circuits in the auditory system. We use mouse genetics to understand how changes in the circuits of the inner ear affect an animal’s ability to detect and perceive sound. Projects employ a variety of techniques, including biochemical analysis of novel proteins, in vitro culturing of inner ear neurons, imaging of single cells during auditory circuit assembly, and gene expression profiling of wild-type and mutant cells. No experience with the auditory system is required, but a familiarity with neuroscience or mouse genetics is a plus. Individuals with expertise in cell biology, imaging, microarrays, or signal transduction are particularly encouraged to apply.

Please send a cover letter, CV, and three references to:

Dr. Lisa Goodrich


Dept of Neurobiology, Harvard Medical School
220 Longwood Avenue
Goldenson 442
Boston, MA 02115

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Higgins Laboratory at Harvard Medical School
Research Area:  Mechanistic Mathematical Modeling of Human Disease Processes with Clinical Data

Description:  The Higgins Laboratory (Department of Systems Biology) has an opening for a postdoctoral fellow to study in vivo human blood cell population dynamics, characterizing rates of immunologic and hematologic processes and their fluctuations during times of health as well as when perturbed by diseases including infection, cancer, and diabetes, both acutely and chronically. 

Qualified applicants will have extensive knowledge of and interest in human pathophysiology, dynamical systems, numerical methods, and good software engineering practices.  For example, strong candidates would be able to compare and contrast the following:  finite elements and finite differences, lymphocyte and myelocyte, quicksort and bubble sort.  Applicants should have a Ph.D. and/or M.D. degree or be in the final year of their doctoral studies, and at least a strong undergraduate background in math, computer science, and engineering.  Interested individuals should apply by submitting an updated CV, complete contact information for three references, and a cover letter describing past research experience, research interests, and career goals.

Mootha Laboratory at Harvard Medical School
The Mootha laboratory (Department of Systems Biology) has a funded opportunity for a postdoctoral scientist in computational genetics.
The laboratory focuses on mitochondrial biology and disease and consists of a lively group of computational biologists, experimental biochemists, and physician-scientists. We are currently seeking a postdoctoral scientist to work at the interface of human genetics and systems biology, with the goal of analyzing very large scale human genome sequence datasets using network models of mitochondria derived from cellular and biochemical studies, to address questions spanning disease, epistasis, and evolution.
 Applicants should possess a Ph.D. and/or M.D. degree in computational biology, preferably with a proven track record in computational genetics and analysis of next-generation sequencing data. Interested individuals should send a cover letter, curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to
 For additional information please visit our webpage:

Fontana Laboratory at Harvard Medical School
The Fontana Laboratory is seeking two outstanding post-docs to accomplish in collaboration with other groups a prototype end-to-end pipeline that extracts detailed mechanistic information about protein-protein interactions from databases and text, assembles such information into executable reference models for the purpose of understanding their dynamical behavior and assessing the current knowledge base in specific cell signaling systems. A can-do attitude, hacker soul, originality coupled to team spirit, fearlessness, and dedicated work ethic are necessary characteristics. Pay is commensurate to experience.
 Position 1: Computer science / AI / bioinformatics / databases
The ideal candidate combines an interest, and possibly expertise, in Artificial Intelligence (text extraction, natural language processing, reasoning) with bioinformatic skills. The individual will collaborate with other groups in excavating information about molecular interactions from extant databases and text; organizing such information for translation into a formal and executable format from which models of cellular signaling are constructed. The candidate should be capable of scripting in Python or Perl, be familiar with procedural and functional programming paradigms (e.g. Java or similar and OCaml or similar) and have database experience.
Position 2: Modeler / cellular signaling / cancer pathways
The ideal candidate is a computational biologist with experience in modeling dynamical systems. The individual is a skilled programmer (C, C++ or similar, experience with OCaml a plus) who will work with Kappa, a formal agent-based modeling language ( and associated tools. Ease with formal / mathematical thinking is required. A sound instinct for molecular biology coupled to a physics mindset is highly desirable. The position functions as a modeling keystone within an ambitious project seeking to build large dynamic “reference models" of cell signaling networks involved in RAS-related cancers. Models of such networks are assembled using mechanistic knowledge extracted from databases and texts in collaboration with outside groups providing pertinent expertise.

To apply, send CV and a covering letter to Walter Fontana:

Megason Laboratory at Harvard Medical School
A postdoctoral research fellow position is available in the Megason lab in the Department of Systems Biology at Harvard Medical School in the areas of embryology, genetics, imaging, and systems biology. The Megason Lab has initiated a project to generate a Digital Fish which is a computer recreation of how the genome is executed to turn an egg into an embryo. We combine novel imaging technologies called in toto imaging to extract quantitative molecular and cellular data from living, developing zebrafish embryos for use in modeling. In toto imaging uses confocal and 2-photon microscopy to image and track every cell in developmental processes to reconstruct complete digital cell lineages. We also are developing a novel genetic approach called FlipTraps which generate endogenously expressed fluorescent fusion proteins and Cre condtional alleles. We combine these approaches to generate quantitative models of how systems of molecules program cells and systems of cells program tissues. Additionally, we are particularly interested in applicants with experience, expertise, and interest in home built 2-photon microscopy systems. For more information please contact Sean Megason ( or visit our website

A cover letter detailing your research motivations and a curriculum vitae should be sent by email to the above address together with the names of three referees with contact information.

Sean Megason, PhD
Department of Systems Biology
Harvard Medical School
200 Longwood Avenue, WAB 536
Boston, MA 02115

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Posted: November 22, 2017

A postdoctoral research fellow position is available in the laboratory of Dr. Andreia Ionescu at Harvard School of Dental Medicine in Boston. We are seeking Postdoctoral candidates who are independent, highly motivated and career-oriented to work on NIH-funded projects in the areas of cartilage development and disease (osteoarthritis). The successful candidate will be involved in identification of the gene signature of cartilage progenitor cells.

Potential candidates should have experience working with molecular biology, stem cells, tissue culture techniques, and mouse models. Expertise in DNA manipulations and generating stable cell lines using Lentiviral vectors and the CRISPR/Cas9 system is desirable. A strong background in molecular and cellular biology as well as Rna-seq and ChIP-seq analyses will receive higher priority. Prior experience with stem cell biology is a plus.

To apply, send your CV and email addresses of three references to:
Dr. Andreia Ionescu, PhD,
Dep. of Developmental Biology, Harvard School of Dental Medicine, 188 Longwood Ave, Boston, MA 02115. Tel: 617-432-5912

For more information, visit our website at:


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Postdoctoral Fellows Positions at the Wyss Institute for Biologically Inspired Engineering
The Wyss (pronounced "Veese") Institute for Biologically Inspired Engineering uses Nature's design principles to develop bioinspired materials and devices that will transform medicine and create a more sustainable world.
 Working as an alliance among Harvard's Schools of Medicine, Engineering, and Arts & Sciences, and in partnership with Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Dana Farber Cancer Institute, Massachusetts General Hospital, the University of Massachusetts Medical School, Spaulding Rehabilitation Hospital, Tufts University, and Boston University, the Institute crosses disciplinary and institutional barriers to engage in high-risk research that leads to transformative technological breakthroughs.
Visit the Wyss Institute's website to find out positions available:

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