Open Postdoc Positions

Postdoctoral Positions at HMS Quad-based Labs

The Dean's Postdoctoral Fellowship | Curriculum Fellows ProgramBiological Chemistry and Molecular Pharmacology | Biomedical Informatics | Cell Biology | Center for Bioethics | Genetics | Global Health and Social Medicine | Harvard Catalyst | Health Care Policy | ImmunologyMicrobiology | Neurobiology | Systems Biology | Harvard School of Dental Medicine | Wyss Institute

This page lists some of the postdoctoral positions currently available on the HMS Quadrangle. Many principal investigators do not advertise their postdoctoral positions with us, so if the PI you want to work with isn't listed here, please contact her/him directly. Please do not send your CV to the administrator of this page.
For non-Quad or external positions please see: postdoc.hms.harvard.edu/job-opportunities

Quad Departments: to have an opportunity listed on this page, send along a description of the postdoctoral position and contact information to us HERE. Please direct any questions to postdoc_office@hms.harvard.edu.

Postdoc openings at other Harvard affiliated institutions:
Beth Israel Deaconess Medical Center | Brigham & Women's Hospital | Children’s Hospital | Dana-Farber | Joslin | Mass General Hospital * | McLean Hospital* | T.H. Chan School of Public Health*
*Please note: some Harvard affiliates do not advertise individual postdoc positions with us, it may be best to identify a PI conducting work in your specific area of interest, and to email that PI directly with your CV and cover letter.


~FEATURED FELLOWSHIP OPPORTUNITIES~

The Laboratory of Systems Pharmacology at Harvard Medical School

The Project Management Fellows Program provides postdoctoral fellows with a mix of hands-on and curriculum-based training in the facilitation of complex research in academic and industrial settings. Many NIH-funded research centers mandate or strongly encourage the inclusion of scientific managers and coordinators in research. This creates new career opportunities for skilled scientists interested in supporting the interdisciplinary, multi-investigator projects typical of contemporary biomedical science. The LPM program helps individuals take advantage of this opportunity by providing hands-on and curriculum-based training in facilitating complex research projects.

The Laboratory of Systems Pharmacology (LSP) at Harvard Medical School tackles difficult problems in translational biomedicine using systems pharmacology approaches that combine laboratory experiments, computer science and clinical studies. Within the LSP, experts in systems biology, basic and translational pharmacology, cell biology, infectious disease, clinical trials, and informatics work closely together to meet the goals of ambitious research programs funded by NIH center and program grants.
LSP projects involve collaboration among multiple faculty members, staff scientists and trainees with very different sets of skills and often based in different departments or institutions. These multi-investigator projects are facilitated by PhD-level scientific managers who help coordinate and integrate the different aspects of each large research project, including pipelines for managing diverse omic data, reagent verification, data curation and validation and communication with the larger scientific community. Scientific program managers play a key role in writing reports for funding agencies, coordination of scientific meetings and often contribute to scientific papers. The LSP scientific program managers will provide LPM fellows with guidance, peer support and mentorship through formal and informal mechanisms.

The Project Management Fellows Program
LPM Fellows will have the opportunity to acquire and refine the required for the effective coordination of large collaborative projects, and obtain Project Management Professional (PMP) certification, a designation required or strongly preferred by employers in industry and government.
Each LPM Fellow will gain hands-on experience in the coordination of multiple research projects and learn the basics of grant management by supporting an NIH Center or Program Project research team within LSP. Fellows will also engage in a rigorous professional development program that draws directly on and supports their project management role in the LSP. Fellows will complete the MassBio Project Management for Biotech course (8 evenings), LSP-based skills assessment and communication workshops, and will be expected to enroll in other short courses at Harvard University specific to their own interests (e.g. “Research administration of sponsored awards”, “Difficult conversations”, “Introduction to management in research”, “Managing up”). The Fellow will independently prepare for the Project Management Exam using the Lynda preparatory courses and other resources.  All expenses related to training and examination will be covered.
A successful LPM Fellow will, within a 2-3 year training period:
-Demonstrate their ability to facilitate complex research projects,
-Hone written and verbal communication skills,
-Develop a working relationship with funding agencies,
-Engage a network of peers and mentors regionally,
-Become certified as a Project Management Professional.

The skills the Fellows will acquire can provide opportunities for several career paths, including:
-Managing a research program, center or other similar activity in academia, in partnership with a faculty leader.
-Project management for biotech or pharmaceutical industry laboratories.
-Research administration in academe, government or industry
-Program management in a federal agency such as NIH or NSF.

The LINCS LPM Fellowship
The LSP is recruiting a LPM Fellow in support of the NIH Library of Integrated Network-based Cellular Signatures (LINCS)Center based in the LSP (http://lincs.hms.harvard.edu). The HMS LINCS Center was established in October 2010 to develop experimental and computational strategies to identify cell “signatures” that describe how cells respond to different chemical or biological perturbations. As of March 2017, seven centers across the U.S. participate in the NIH LINCS consortium program. The HMS LINCS Center is identifying signatures that measure the responses of cells derived from different human tissues to therapeutic drugs. Much of the work focuses on cultured cells (from breast, liver and colon), but the Center also studies primary human cells from normal and diseased patients.  As perturbing agents, the focus is on small molecule kinase inhibitors, which are a leading class of therapeutic agents for treatment of cancer, autoimmune and other diseases.
In their research management role, the fellow will collaborate with HMS LINCS investigators to:
-Play a prominent role within the HMS LINCS group curating and organizing experimental data.
-Develop and execute plans for LINCS data releases to public repositories.
-Help to coordinate HMS LINCS data production, data annotation and outreach activities with the work of other LINCS centers.
-Participate in LINCS consortium activities, including regular calls for the Steering Committee, Data Working Group, and Experimental Working Group, and in-person meetings.
-Communicate with the NIH program office regarding required reports, data releases, outreach activities and metrics collection.
-Attend and participate in LSP and Sorger lab group meetings and in the regular and ad hoc meetings involving LINCS PIs, postdocs, students and staff
The Fellow will be appointed as a postdoctoral fellow under LINCS PI and LSP Director Peter Sorger, work on a day-to-day basis with postdocs and staff active in LINCS and receive mentorship and guidance from LSP Scientific Managers and Executive Director.  This position will have a high degree of independence, and opportunities to present at regional and national scientific symposia and workshops.

Requirements:
-PhD in cell biology, biochemistry, molecular biology, pharmacology, systems biology, chemical biology, biophysics or related field
-Demonstrated experience or a strong statement of interest in collaborative research
-Excellent written and verbal communication skills
-Strong organizational and interpersonal skills
-Interest in research coordination and project management

Applications should provide a CV, cover letter and 3 letters of recommendation via email to hits@harvard.edu.

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The Dean's Postdoctoral Fellowship

Co-Sponsored by: The Office for Diversity Inclusion and Community Partnership and The Office for Postdoctoral Fellows

As part of an effort to promote a diversity of backgrounds, perspectives, and experiences among its faculty and trainees, Harvard Medical School invites applications for the Dean’s Postdoctoral Fellowship.
The Office for Diversity Inclusion and Community Partnership in collaboration with The Office for Postdoctoral Fellows will award two-year postdoctoral fellowships per year to two promising researchers in the fields of basic or social sciences. The Dean’s Postdoctoral Fellowship at Harvard Medical School will prepare postdoctoral scientists, particularly scientists from minority and disadvantaged backgrounds, for cutting-edge research careers.  This fellowship will position the right candidate to make major contributions as scientific and societal leaders.
Fellows will benefit from a highly innovative and creative research environment that emphasizes scientific rigor, collaboration, and the pursuit of excellence in science.  In addition, Fellows are welcome to join the HMS the Society for Translational and Academic Researchers (STARs), sponsored by the Office for Diversity Inclusion and Community Partnership
 (https://mfdp.med.harvard.edu/stars)
For more info or to apply: http://www.hms.harvard.edu/dcp/deanspdfellowship/index.html

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The Harvard Medical School Curriculum Fellows Program (CFP)

The Curriculum Fellows Program (CFP) is pleased to announce a Curriculum Fellow position in Developmental and Regenerative Biology (DRB).  (posted 3.13.19)
The Harvard Medical School (HMS) Curriculum Fellows Program (CFP) invites applications for a Curriculum Fellow in Developmental and Regenerative Biology (DRB) to develop and support educational programming in the DRB graduate program administered by the Department of Stem Cell and Regenerative Biology, the first cross-school department in the University. The CFP is a postdoctoral service and training program focused on curriculum development, teaching, and educational programming in the biological and biomedical sciences. The Curriculum Fellow (CF) in DRB will primarily work with DRB leadership and faculty to develop, implement, and assess educational programming aligned with current demands of the training landscape and which will prepare DRB students for success in a wide range of careers. Fellows also receive mentorship and career advising to support their development as educators and help them succeed in a variety of education-focused careers. More detailed information about the Curriculum Fellows Program and the role of a CF can be found in the 2019 CF cohort announcement available on our website (https://curriculumfellows.hms.harvard.edu/home). 

Specific Responsibilities:
- Work closely with the faculty directors to organize and oversee the core graduate course in DRB (“Experimental Approaches to Developmental Biology”) to develop course materials and assessments, coordinate TA activities, and manage online course content
- Organize and implement DRB orientation programming
- Provide academic support to DRB faculty to facilitate the creation of new elective courses
- Organize and participate in activities to build and foster a sense of community among the graduate community across campuses (particularly Longwood and Cambridge)
- Participate in other key courses and programs of interest taught on either the Longwood or Cambridge campuses
- Help to collect and organize information on program alumni

Qualifications:   
- An earned doctorate in developmental biology or related field
- Experience teaching graduate or undergraduate students
- Postdoctoral research and/or teaching experience is preferred but not required

Job Skills and Competencies:
- Broad content knowledge in the field of developmental biology that will enable the CF to effectively partner with faculty to design new educational resources
- Ability to work collaboratively with multiple faculty and administrative partners across different campuses to develop new courses and educational/training opportunities
- Experience applying pedagogical best practices to the classroom, including evidence-based teaching methods and technological innovations
- Strong oral and written communication skills, strict attention to detail
- Strong organizational and administrative skills and the ability to successfully plan and implement programs and events
- Ability to work independently to identify and implement optimal solutions to diverse problems

The CF’s appointment is renewable annually for a maximum of three years and is non-tenure-track. Fellows are appointed as research associates, with possible promotion to the rank of Lecturer contingent on experience and performance.
The ideal start date is Summer/Fall 2019 at Harvard Medical School in Boston, MA. Candidates will be interviewed by phone or Skype before selections are made for on-campus interviews.
To apply: 
Applicants should email a single PDF document containing:
- a letter of application that describes your interest in and qualifications for the position
- a curriculum vitae
- a statement of teaching philosophy

Address emails to cfp@hms.harvard.edu, attention Dr. Bradley Coleman, Co-Director of the HMS Curriculum Fellows Program. Include the names and contact information of three references, who will be contacted during the review process. The review of applications will begin Monday, April 8th, 2019.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy, and pregnancy-related conditions or any other characteristic protected by law.

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Curriculum Fellows Program - Online Learning in Immunology  (posted 1.30.19)
https://curriculumfellows.hms.harvard.edu/HMX-IMM19

The Harvard Medical School (HMS) Office of Online Learning and the Curriculum Fellows Program (CFP) are pleased to announce an opening for a post-doctoral Curriculum Fellow (CF) who will develop a series of short online Immunology courses and contribute to the development of other online courses. The Curriculum Fellow for Online Learning in Immunology will be an integral member of the team at HMX – an initiative at HMS producing fully online courses that are offered to students all over the world who may be interested in a variety of health care careers (e.g. medicine or nursing). These courses teach foundational medical topics in a highly applied, engaging, and visual manner. HMX is a fast-paced and highly collaborative team, bringing together the expertise of teaching and learning experts, medical illustrators, videographers, medical professionals, and technologists. If you have insight and expertise in teaching immunology, and are a project manager, team player, curious researcher, motivated problem solver, and fearless innovator, this is the job for you.  https://onlinelearning.hms.harvard.edu/hmx

The CFP is a service and training program for early career scientists who are focused on curriculum development, teaching, and educational programming in the biomedical and biological sciences. Curriculum Fellows work closely with committed members of the HMS faculty and administration to develop, deploy, and evaluate evidence-based graduate and medical education and training. Fellows also receive mentorship and career advising to support their development as educators and have gone on to a variety of education-focused careers. More detailed information about the Curriculum Fellows Program and the role of a CF can be found in the 2019 CF cohort announcement available on our website (https://curriculumfellows.hms.harvard.edu/job-opportunities).

The Curriculum Fellow for Online Learning in Immunology will focus on the development, improvement, support, and analysis of a high-quality online curriculum in the basic medical sciences, with an emphasis on clinically relevant concepts and applications of basic science knowledge in the practice of medicine. Working in an HMX team, the CF will collaborate with faculty to design and develop multimodal online modules. The CF will manage and develop the curriculum for a series of new short Immunology courses, including videos, problem sets, assignments, and assessments, with the opportunity to take a fresh approach to curriculum design and creation. The CF will contribute to a research strategy to investigate the impact of the program on student learning and engagement. Online module development is overseen by the Associate Director for Teaching and Research in conjunction with the Associate Dean for Online Learning. The CF will be co- mentored by science/content experts as well as online learning experts. The CF will contribute to program delivery and coordinate appropriate follow-up to drive continuous course and program improvement. Supervisory responsibilities may include the training and mentoring of Online Learning staff and/or student interns. The CF appointment is renewable annually for a maximum of three years and is non-tenure-track. Fellows are appointed as research associates, with possible promotion to the rank of Lecturer contingent on experience and performance.

Minimum Qualifications:
An earned M.D. or Ph.D. in the biomedical sciences as of February 2019
A strong content background and teaching experience in immunology or closely related topics

Desired Qualifications and Qualities:
-Excellent organizational, time management, and planning skills
-Well-developed writing and self-editing skills, with an intense attention to detail
-Dedication to producing consistently high-quality work and seeing projects through to
completion
-Track record of working in highly collaborative team settings
-Commitment to tackling new topics and problems with creativity and enthusiasm
-Demonstrated interest in teaching or a track record of excellent teaching, in-person or online, including a passion for helping students visualize and understand complex concepts
-Strong interest in online education and the applications of technology in higher education
-Willingness to teach in new ways, including appearing on camera, writing excellent assessment questions, and creating “whiteboard” style teaching videos

To apply:
Multiple CF positions are currently open at Harvard Medical School. These are listed at the CFP web site – https://curriculumfellows.hms.harvard.edu/job-opportunities. Qualified candidates are welcome to apply for more than one of these positions with a single application. The ideal start date for the Curriculum Fellow for Online Learning in Immunology is on or before April 1, 2019 at Harvard Medical School in Boston, MA. Candidates will be interviewed by phone or Skype before selections are made for on-campus interviews.

Interested candidates should email a single PDF document containing:
(1) a letter of application that clearly identifies the specific curriculum fellow position or positions to which you are applying, including your interest in and qualifications for the position
(2) a curriculum vitae
(3) a statement of teaching philosophy

Address emails to cfp@hms.harvard.edu, attention Dr. Bradley Coleman, Co-Director of the HMS Curriculum Fellows Program. Include the names and contact information of three references, who will be contacted during the review process. The review of applications will begin Tuesday, February 19th, 2019.
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.

(posted 1.30.19)
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Curriculum Fellows Program - HMS Program in Graduate Education (2019)
Harvard Medical School (HMS) seeks talented early-career scientists interested in a career in education to apply for a three-year fellowship within the HMS Curriculum Fellows Program (https://curriculumfellows.hms.harvard.edu).

Curriculum Fellows work closely with committed members of the HMS faculty and administration to develop, deploy, and evaluate evidence-based graduate biomedical education and training. Fellows have gone on to careers as directors of curriculum in a variety of academic programs, leaders in centers for teaching and learning, discipline-based educational researchers, faculty at teaching-focused undergraduate institutions, and administrators of higher education.

The majority of each fellow’s time is spent serving the curricular and programmatic goals of the specific academic department or graduate training program that hires them (see below for the current openings). In addition, fellows create curricular and para-curricular programming for biomedical graduate training across HMS, gain experience in the application of evidence-based teaching practices, and are provided with highly individualized professional development opportunities. Fellows are expected to contribute to the HMS community by attending and presenting in workshops, an education journal club, and pedagogy-focused seminars. Collaborations to improve training across the HMS Program in Graduate Education are encouraged and opportunities may exist to teach undergraduate courses and/or conduct discipline-based educational research (DBER) — in both cases either in- or outside the scope of the fellows’ primary service.

Suitable candidates will have a PhD in a scientific field that adequately prepares them to develop graduate-level curricula specific the hiring program or department. Demonstrated interest and experience in scientific teaching is required, preferably at the graduate or undergraduate level. The fellowship is intended for early-career scientist-educators. Therefore, applications from candidates with more than 5 years of postdoctoral research or teaching experience are discouraged. Fellows are appointed as Research Associates, with possible promotion to the rank of Lecturer contingent on experience and performance.

Details about the specific responsibilities and subject expertise required for each of the currently available fellow positions can be found at the CFP website:
https://curriculumfellows.hms.harvard.edu/job-opportunities
Curriculum Fellow in Genetics and Genomics
Curriculum Fellow for the Program in Neuroscience
Curriculum Fellow in Online Learning and Immunology
Curriculum Fellow in Cell Biology
Curriculum Fellow in Developmental and Regenerative Biology

To Apply: Qualified candidates are welcome to apply for more than one of these positions with a single application. Candidates will be interviewed by phone or Skype before selections are made for on-campus interviews.
Applicants should email a single PDF document containing:
(1) a letter of application that clearly identifies the specific curriculum fellow position or positions to which you are applying, including your interest in and qualifications for the position
(2) a curriculum vitae
(3) a statement of teaching philosophy

Address emails to cfp@hms.harvard.edu, attention Dr. Bradley Coleman, Co-Director of the HMS Curriculum Fellows Program. Include the names and contact information of three references, who will be contacted during the review process. The review of applications will begin Tuesday, February 19th, 2019. Curriculum Fellows are located in the Longwood Medical Area in Boston, MA.
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.

 

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~DEPARTMENTAL LISTINGS~

BIOLOGICAL CHEMISTRY AND MOLECULAR PHARMACOLOGY

The Coen Lab
Postdoctoral position available. The Coen lab in the Dept. of Biological Chemistry & Molecular Pharmacology at Harvard Medical School has an opening for a postdoctoral fellow to work on herpesvirus DNA replication and nuclear egress. Experience in cloning, mutagenesis, expression, purification, and biochemical and/or biophysical analyses of proteins is required; experience with baculovirus expression is desirable but not required. If you are interested, please email your CV and the names and email addresses of three references to don_coen@hms.harvard.edu(Posted 1.22.19)

The Arthanari Lab
The Arthanari Lab at Department of BCMP, Harvard Medical School and Department of Cancer Biology, Dana Farber Cancer Institute is seeking a highly motivated postdoctoral candidate with expertise in transcriptional biology. Our laboratory works at the interface of structural biology, drug discovery and mechanistic biology, focusing on transcription factors and their interactions with co-activators and mediators (e.g. Nature 2016 25;530 (7591): 485-9; Nature 2008 452 (7187): 604-9). Research efforts will be focused on the intersection of cancer biology/genetics and immune-oncology. The candidate is expected to have a comprehensive understanding of signaling pathways, epigenetics and transcription regulation. Experience in technical skills including cell culture, somatic genetic analysis (e.g., CRISPr, si-, sh- RNA knockdown and rescue), protein biochemistry, assay design and development and biological applications to advance discovery are preferred. The individual should be independent and passionate about science and have an established record of creativity, ability to work in teams and strong publication record in peer-reviewed scientific journals.
Interested applicants should send a CV, and the names/phone numbers of three references by email to hari@hms.harvard.edu

Blacklow Laboratory at Harvard Medical School
The Blacklow Laboratory at Harvard Medical School (Department of Biological Chemistry and Molecular Pharmacology) has an opening for a Postdoctoral position. The laboratory currently investigates structure-function relationships in Notch signaling, its downstream targets, and its epigenetic regulators.
Applicants should possess a Ph.D. and/or M.D. degree in Molecular Biology, Cell Biology, Biochemistry, Structural Biology or a related field.
Interested individuals should send a cover letter, curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to jobs_blacklowlab@hms.harvard.edu.

The Brown Laboratory
Postdoctoral Fellow in Electron Cryomicroscopy (Full posting: https://brown.hms.harvard.edu/jobs/93)
Position Description: A postdoctoral position is available in the Brown lab at Harvard Medical School. The lab uses the latest developments in cryo-EM to understand biological processes at the molecular level (e.g. Nature 524, 493–496 and Science 346, 718–722). The project will involve investigating the structure and function of large macromolecular complexes involved in cellular transport. This includes all steps from construct design to structure determination. In the long term, we aim to use detailed molecular models to facilitate the development of new and better therapeutics.
Job requirements: Applicants should hold (or will be shortly awarded) a PhD degree and have experience in molecular biology and protein purification. Prior experience with single-particle cryo-EM or X-ray crystallography is considered a major advantage. Candidates should have strong communication skills and an established record of creativity through principal authorship in peer-reviewed publication(s). The successful candidate should be passionate about science, motivated, proactive, and able to work in a team. While each lab member has their own project, lab members are encouraged to work together to solve common problems. A separate position is available for an outstanding candidate with expertise in electron cryotomography (cryo-ET).
The position is initially for 2 years with a possibility of extension.
If you’re interested in joining the lab, please send your CV with a brief description of your current research as well as 2-3 contacts for references to Alan_Brown@hms.harvard.edu before the 8th August, 2017.

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BIOMEDICAL INFORMATICS

Postdoctoral Positions in the Lab of Paul Avillach (posted 2.12.19)

Phenotype extraction and biomedical ontologies
Summary
The Department of Biomedical Informatics (DBMI) at Harvard Medical School is looking for a Postdoctoral Fellow to help build cutting edge research platforms. The real value in biomedical research lies not in the scale of any single source of data, but in the ability to integrate and interrogate multiple, complementary datasets simultaneously. We are combining clinical and genomics data across different scales and resolutions to enable new perspectives for essential biomedical questions. The research focuses on the development of novel methods and techniques for the integration of multiple heterogeneous clinic cohorts, Electronic Health Records data and multiple types of genomics data to encompass biological observations.

Responsibilities
The Postdoctoral Fellow will be responsible for developing novel methodologies and applications to facilitate high-throughput phenotype extraction, harmonize content with biomedical ontologies and integrate clinical and molecular genomic data.
The diversity of subject matter will require a creative mind and a candidate capable of deploying imaginative strategies and who is dedicated to solving complex and challenging problems within an interdisciplinary environment.

Basic Requirements
Candidates must have a PhD degree (or MD/PhD) in biomedical informatics, bioinformatics, Computational Biology, computer science, or a related field. Curriculum in and/or experience with standardized ontologies, terminologies, metadata, and related technologies as well as experience in programming and software development will be necessary for this opportunity. The candidate interested in this position must be highly motivated, willing to learn and demonstrate initiative in assigned tasks. Excellent written and verbal communication skills are crucial.

Additional Requirements
Preferred requirements for this position include experience with the Unified Medical Language System (UMLS), statistics, data mining and machine learning. Experience with R, Python, and/or Perl is desirable.

Terms
The position is available immediately and can be renewed annually.

How to apply
Email applications including curriculum vitae, summary statement of personal objective and research interests, PDFs of the best two papers, and the names and email addresses of three references to paul_avillach@hms.harvard.edu

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Visualization of biomedical data
Summary
The Department of Biomedical Informatics (DBMI) at Harvard Medical School is looking for a Research Fellow to help us build cutting edge research platforms. We seek an individual to work on our multidisciplinary team of data scientists, medical doctors, and developers. Our team studies large and disparate datasets from the domains of biology, healthcare and social media. The goal of our efforts is to transform human healthcare and research to usher in a new age of individualized data driven medicine.
The Research Fellow will be responsible for developing novel methodologies and applications to help visual causal relationships in bioinformatics data sets. The diversity of subject matter will require a creative mind and a candidate capable of deploying imaginative strategies and who is dedicated to solving complex and challenging problems within an interdisciplinary environment.

Responsibilities
The Research Fellow will work to understand data about causal relationships in order to develop visualizations, create prototypes for visualizations and work with software professionals to integrate the work into an existing platform, and perform novel research on bioinformatics data sets along with publish any findings.

Basic Requirements
PhD degree (or MD/PhD) in Biomedical Informatics, Bioinformatics, Computational Biology, Computer Science, Mathematics, or a related field; Curriculum in and/or experience with demonstrated ability to extract insight from large volumes of data using data mining and the creation of effective visualization techniques; Experience in programming and software development; Excellent written and verbal communication skills.

Additional Requirements: Experience with user interaction design; JavaScript; D3 visualization library (or similar); data mining; R; Python, and/or Perl is desirable.

Terms: The position is available immediately and can be renewed annually.
How to apply
Email applications including curriculum vitae, summary statement of personal objective and research interests, PDFs of the best two papers, and the names and email addresses of three references to paul_avillach@hms.harvard.edu

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Postdoctoral Positions in the Lab of Maha Farhat - Infectious Disease Genomics (posted 2/12/19)

Summary
The Department of Biomedical Informatics (DBMI) at Harvard Medical School and the Farhat Lab are looking for a Postdoctoral Fellow in infectious disease genomics.
Pathogens display a remarkable range of variability in phenotypes relevant to disease including transmissibility, organ tropism, and antibiotic resistance. Elucidating the biological mechanisms for these differences is a fundamental question in the study of infectious diseases and creates new avenues for surveillance, diagnosis and personalized treatment. The heritability of disease phenotypes within pathogen species and their evolution over generations indicates that they should be genetically coded. As a result, the study of pathogen whole genome sequences (WGS) data is expected to further our understanding of these traits.  

Responsibilities
The Postdoctoral Fellow will be responsible for developing and applying computational methodologies to identify novel infectious disease genomic markers and to assess their diagnostic and surveillance potential.  

Basic Requirements
We are an interdisciplinary lab. Candidates may have an MD or PhD degree in epidemiology, bioinformatics, computational biology, biostatistics, or a related field. The candidate interested in this position must be highly motivated and demonstrate initiative in assigned tasks.

Additional Requirements
Experience in programming R, Python, and/or Perl and statistical analysis or at least an interest in learning these skills will be necessary. The candidate and PI can work together to delineate the fellow’s training needs and develop a program to fulfill this, utilizing the department and university’s wide range of resources.

Terms: The position is available immediately and can be renewed annually.

How to apply
Email applications including curriculum vitae, summary statement of personal objective and research interests, PDFs of the best two papers, and the names and email addresses of three references to mrfarhat@partners.org.

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Postdoctoral Positions in the Lab of Peter Kharchenko  (posted 2.12.19)
Job Description
The Department of Biomedical Informatics (DBMI) at Harvard Medical School and the Kharchenko Lab is looking to recruit several postdoctoral fellows interested in pursuing one or more of the following topics in computational biology:

Single-Cell Genomics
The fellow will be charged with developing novel statistical approaches to the analysis of single-cell genomic data, mathematical modeling of cellular processes, as well as applications of such techniques to study healthy and diseased tissues. Strong background in statistics, modeling of stochastic processes and multicellular systems is desired.

Computational analysis of epigenetic mechanisms disrupted in cancer and other disease-disrupted tissues
The fellow will be responsible for developing and applying computational methods for integrative analysis of genome-wide epigenetic, transcriptional and proteomic data, aiming to identify specific factors and molecular mechanisms underlying misregulation of the epigenetic states in several types of human cancer. The ideal candidate should have a strong quantitative background, ample experience with analysis of sequencing assays, and strong interest in cancer biology.

Computational analysis of nucleosome organization
The fellow will be part of the central analysis group for the extensive 4D-nucleus consortium project funded by the NIH. The efforts will be focused on the development of analysis techniques for the next generation of experimental methods for measuring organization and dynamics of the eukaryotic nucleus that are being developed by the members of the consortia. Experience with analysis of Hi-C and relevant imaging data is strongly preferred.

All projects are being conducted in close cooperation with the expert bench-side laboratories, providing an excellent opportunity for collaborative research. Harvard Medical School and the Department of Biomedical Informatics also provides for a rich scientific environment, with a number of relevant seminar series, invited speakers, and many neighboring laboratories working on related projects.

PhD in Computational Biology, Statistics, Physics or other related discipline is required. A strong record of publications in the field is desired.

To apply – please send cover letter, curriculum vitae and contact information for at least two references to Dr. Peter Kharchenko at peter_kharchenko@hms.harvard.edu. Applications will be considered until the positions are filled. Please specify which project you are interested in.

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Kharchenko Lab: Postdoctoral Opportunities (posted 1.28.19)
Single-cell Transcriptomics, Epigenetics | Spatially-resolved Transcriptomics | Gene Regulation | Cancer Heterogeneity, Therapy Resistance, Immune Microenvironment | Tissue Organization

A group led by Peter Kharchenko at the Department of Biomedical Informatics of the Harvard Medical School is searching for postdoctoral fellows interested in developing and applying novel statistical, computational and experimental approaches to study challenges posed by cancer biology and development/maintenance of healthy tissues at a single-cell resolution. The research questions are being pursued in close cooperation with expert bench-side laboratories, providing an excellent opportunity for collaborative research. In particular, we are looking for researchers interested in joining our efforts on single-cell atlas of human brain, lung, kidney and other organs as part of the NIH funded BRAIN and HuBMAP consortia. Fellows interested in application of advanced image analysis techniques to study organization of biological tissues are encouraged to apply.

More info at
http://pklab.med.harvard.edu/

Areas of Interest: Single-Cell Analysis, Spatial Analysis, Statistics, Cancer, Tissue homeostasis

Candidate qualifications:
- Robust knowledge of statistical methods, and probabilistic modeling techniques
- Experience with quantitative analysis of modern biological assays
- We welcome experience in image analysis, graphical models, and advanced machine learning
- A strong interest in conducting collaborative research
- Track record of publications in peer-reviewed journals

How to apply: Please send cover letter, curriculum vitae and contact information for at least two
references to Peter Kharchenko at peter_kharchenko@hms.harvard.edu. Applications will be considered until the position is filled.

Employer: Department of Biomedical Informatics has been recently formed at the Harvard Medical School to lead development of computational and informatics techniques to address pertinent challenges in modern biological sciences and medicine. The Department’s faculty conduct research at the intersection of biomedicine and information sciences, including bioinformatics, functional genomics, translational medicine, and clinical knowledge management. The Department also hosts the Bioinformatics & Integrative Genomics PhD program (sponsored by NHGRI) and the Biomedical Informatics Masters program.

Harvard Medical School is an Equal Opportunity/Affirmative Action Employer.

Women and minorities are especially encouraged to apply.

__________

Department of Biomedical Informatics Postdoctoral Position
(posted 7.19.18)

Summary
This position will be based in the Department of Biomedical Informatics at Harvard medical school and will supervised by Andrew Beam, PhD (faculty in the Department of Biomedical Informatics) and Isaac Kohane), MD/PhD (chair of the Department of Biomedical Informatics. The candidate will conduct original research on an exciting problem in the domain of medical question answering and will join a team of researchers working on similar problems in the area of natural language understanding. For this project we have curated a unique data resource of nearly 20,000 medical questions and over 200GB of medical text documents. The goal of this project is to create a cutting-edge system that is capable of answering medical questions posed as free text. 

Qualifications
Candidates must have a PhD or other advance degree in statistics, computer science, biomedical informatics, or a related field. The candidate must have expertise in machine learning and experience programming deep learning models using either tensorflow/keras or pytorch.

Additionally, candidates are required to have expertise in deep learning and natural language processing as evidenced by at least one of the following:
- First-author publication in journal or conference in the field of deep learning or NLP
- First-author preprint of a deep learning/NLP project
- A well-documented github repository of a project written either in tensorflow or pytorch implementing a state of the art NLP model (such as a language model, transformer network, fast text, etc) with an accompanying blog post demonstrating the concepts.

Preferences
Strong preference will be given to candidates with previous experience in the area of automatic question answering. Experience with reinforcement learning, knowledge bases, and medical ontologies is also desired.

Responsibilities
The candidate will be responsible for developing new methodology in the field of question answering and reducing these ideas to practice in python code. They will be expected to collaborate with other members of the lab, present their progress regularly at lab meetings, and to communicate their results to the scientific community through profession meetings and scientific publications.

Start Date
As soon as possible
How to Apply
To be considered for this position, please email a single PDF document containing a letter of application that addresses your interest in and qualifications for the position, and a curriculum vitae. Please include the names and contact information of three references, who will be asked to supply letters or will be contacted by phone early in the application process. This is a one-year term appointment with the option to renew for a second-year conditional on satisfactory performance. The position is available now at Harvard Medical School in Boston.
Address applications to:
Andrew Beam, Ph.D.
Instructor in Biomedical Informatics
Andrew_Beam@hms.harvard.edu
Harvard University is an equal opportunity employer.  Women and minorities are especially encouraged to apply

Avillach Laboratory at Harvard Medical School

Research Fellow Position at the Department of Biomedical Informatics (posted 10/16/15)

Description: The Department of Biomedical Informatics (DBMI) at Harvard Medical School is looking for a Research Fellow to help us build cutting edge research platforms. We seek an individual to work on our multidisciplinary team of data scientists, medical doctors, and developers. Our team studies large and disparate datasets from the domains of biology, healthcare and social media. The goal of our efforts is to transform healthcare and research to usher in a new age of individualized data driven medicine.
The Research Fellow will be responsible for developing novel methodologies and applications to help visual causal relationships in bioinformatics data sets. The diversity of subject matter will require a creative mind and a candidate capable of deploying imaginative strategies and who is dedicated to solving complex and challenging problems within an interdisciplinary environment.
Specific responsibilities for this position include:
• Work to understand data about causal relationships in order to develop visualizations.
• Create prototypes for visualizations and work with software professionals to integrate the work into an existing platform.
• Perform novel research on bioinformatics data sets and publish any findings.

For details and additional information: http://avillach-lab.hms.harvard.edu


Gehlenborg Laboratory at Harvard Medical School

Multiple postdoctoral fellowships are available immediately in the Gehlenborg Lab in the Department of Biomedical Informatics at Harvard Medical School. (posted 10/21/15)

Description:
The goal of the lab is to improve human health by developing computational techniques and interfaces that enable biomedical and clinical investigators to efficiently interact with biomedical data. We design, implement and evaluate methods and tools that leverage the knowledge and cognitive skills of investigators in order to enable the interpretation of massive heterogeneous data sets that integrate genomic and clinical data. Please see http://gehlenborglab.org for additional information about our work.

Possible research projects include development of data visualization, analysis, and management tools to study genomic structural variants, dynamics of the 3D genome, and cancer subtypes in patient cohorts. Further projects involve the design and implementation of visual exploration tools for biomedical data repositories and tools for viewing and interacting with provenance graphs. All of the projects are highly interdisciplinary and are being conducted in close cooperation with computational or experimental domain experts providing an excellent opportunity for collaborative research.

Our lab in the Department of Biomedical Informatics is part of a vibrant community of scientists, physicians, and engineers whose goal is to advance the boundaries of knowledge. The Department has recently been formed at Harvard Medical School to lead development of computational and informatics techniques to address pertinent challenges in modern biological sciences and medicine. The Department’s faculty conduct research at the intersection of biomedicine and information sciences, including bioinformatics, functional genomics, translational medicine, and clinical knowledge management. Based on the Harvard Medical School Longwood Campus, it provides a rich scientific environment, with many seminar series and invited speakers of the highest caliber.

For details and additional information: https://dbmi.hms.harvard.edu/careers/postdoctoral-fellows/gehlenborg-lab

Kharchenko Laboratory at Harvard Medical School

A laboratory at the newly-formed Department of Biomedical Informatics at the Harvard Medical School (HMS) is looking to recruit several postdoctoral fellows interested in pursuing one or more of the following topics in computational biology:
I. Single-Cell Genomics
II. Computational analysis of epigenetic mechanisms disrupted in cancer and other disease-disrupted tissues
III. Computational analysis of nucleosome organization
(posted on 2/4/16)

For details and additional information: https://dbmi.hms.harvard.edu/careers/postdoctoral-fellows/kharchenko-lab

 

Patel Laboratory at Harvard Medical School

The Patel Group in the Harvard Medical School Department of Biomedical Informatics (http://chiragjpgroup.org) is looking for a Post-Doctoral research fellow to run a collaborative study with Northeastern University’s Antimicrobial Discovery Center that will uncover the characteristics of Lyme disease around the US leveraging emerging large and high-dimensional clinical data streams. Candidates must have a PhD in computer science, mathematics, physics, biomedical informatics, bioinformatics, or a related quantitative field. Preferred qualifications for this position include experience designing large software applications and infrastructure to store, retrieve, and analyze large datasets. Industry experience with R, Python, SQL is required. Experience in hacking with cloud technologies is great. Email applications including curriculum vitae, summary statement of personal objectives, and the names and email addresses of 2-3 references to Chirag Patel (chirag_patel@hms.harvard.edu). Harvard Medical School is an Equal Opportunity/Affirmative Action Employer. Women and minorities are especially encouraged to apply. (posted 3/2/16)

Biomedical Data Scientist Postdoctoral Associate (posted 2/4/16)
Imagine a dynamic dataset that encompasses comprehensive information about a patient in the health care system: what diseases they have, their genomic sequence, their social media messages (e.g, tweets and likes), and where they live. How would you—a data hacker—store, retrieve, and analyze this information to drive biomedical discovery to find a new way of predicting disease or even a new therapy for a disease? Chirag Patel’s Group at the Department of Biomedical Informatics at Harvard Medical School is looking for a data engineer to build cutting-edge platforms and data infrastructure to enable large-scale data-driven research to address this question. We aim to integrate diverse data sources from geotemporal information (e.g., NOAA Weather Data, EPA AirData), individual genomic sequence, social media data, and health claims information to paint a comprehensive picture of individuals who are sick and healthy.

For details and additional information: https://dbmi.hms.harvard.edu/careers/postdoctoral-fellows/patel-group


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CELL BIOLOGY

Yuan Laboratory at Harvard Medical School
The Yuan laboratory at Harvard Medical School (Department of Cell Biology) has an immediate opening for a postdoctoral scientist. Our laboratory investigates the molecular mechanisms of cell death, including necroptosis and apoptosis, and their relevance for human diseases. This position is for a highly motivated individual with considerable experience in cell biology or related field. Experience in animal models of human diseases is desirable but not required.

Applicants should possess a Ph.D. and/or M.D. degree in molecular biology, cell biology, biochemistry, or neurobiology and a strong publication record. Interested individuals should send a curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to junying_yuan@hms.harvard.edu.

For additional information please visit our webpage: https://yuan.med.harvard.edu/


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CENTER FOR BIOETHICS

The Harvard Medical School Center for Bioethics invites applications for the Postdoctoral Research Scholars Program in Bioethics, for appointments commencing in summer/fall 2018.

This 1-2 year program prepares scholars with the knowledge and skills necessary to become leaders in the field of bioethics. Research scholars are fully integrated into the community of faculty and students at the Center for Bioethics, with access to the resources of Harvard Medical School and Harvard University. The program includes opportunities to collaborate with the scholars at the Hastings Center. We are particularly focused on attracting candidates with an interest in working on ethical and policy issues in regenerative and synthetic biology, genetic engineering, stem cell biology and embryology. Ideal candidates would be promising scientists in these areas with a background in bioethics or with a serious commitment to gaining expertise in the field
Research scholars will receive an annual stipend, benefits, and an allotment for academic expenses and travel.

The core experience includes:

  • Mentored research. Research scholars work closely with faculty mentors from across Harvard University to develop and conduct original research in the field of bioethics. A primary aim of the program is to prepare candidates with the training necessary to obtain competitive research funding and develop a successful academic career in bioethics.
  • Educational opportunities. The program seeks candidates with diverse backgrounds, experience, and knowledge. Each scholar works with faculty creating a personalized educational program that will delve into special areas of interest, as well as developing broad expertise in the field of bioethics. Research scholars have access to all the Center's courses and seminars, and may be able to audit relevant courses across Harvard University with faculty permission.
  • Community life. Postdoctoral research scholars will be fully engaged with the activities of the Center and the Harvard-affiliated teaching hospitals. Scholars will organize and conduct conferences and seminars, they will assist in teaching courses in their areas of interest, and will have opportunities to participate on hospital clinical ethics committees and institutional review boards.

In short, the Postdoctoral Research Scholars Program provides the greatest possible access to all that Harvard University has to offer.

Application Requirements:
Applications are invited from those who have or will have completed a doctoral degree (MD, JD, PhD or equivalent) by July 1, 2018. Doctorates may be in any relevant field, including but not limited to public health, psychology, economics, philosophy, sociology, or anthropology.
The deadline for summer/fall 2018 is March 30, 2018. Applications may be considered throughout the year under special circumstances.
Visit the website for application requirements: 
http://bioethics.hms.harvard.edu/postdoctoral-program


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GENETICS

Genetics - Postdoctoral fellow in Aging at Harvard Medical School (posted 6.1.18)

A postdoctoral fellow position is available immediately in the Department of Genetics at Harvard Medical School to study the biology of aging. The position will be funded by a 5-year R01 research grant entitled “Molecular mechanisms by which mild elevation of mitochondrial superoxide extends longevity” under the direction of Dr. Jeremy Van Raamsdonk, in Dr. Monica Colaiacovo’s lab. Dr. Van Raamsdonk, seeks to understand the aging process and to use that information to promote healthy aging and decrease the severity of age-onset neurodegenerative disease. The laboratory primarily uses C. elegans as a genetic model organism, prior to validating results in mouse models.

For a list of publications from Dr. Van Raamsdonk and the Van Raamsdonk lab please see: https://scholar.google.com/citations?user=WEaryu0AAAAJ&hl=en&oi=ao

Required Qualifications:
-Ph.D. in a related field of biology (e.g. genetics, neuroscience, molecular biology)
-Extensive experience working with C. elegans
-Ability to generate transgenic worms from design to cloning to microinjection to integration
-Previous experience with molecular biology techniques (DNA, RNA, protein)
-Ability to work independently and as part of a team
-Ability to lead a research project from design stages to data analysis, figure preparation and manuscript writing
-A passion for scientific research
-Strong organization and time management skills
-Meticulous attention to detail
-Eligible to work/train in the United States

Additional expertise that would be beneficial:
Experience with Crispr-Cas9 genome editing techniques
-Experience and interest in designing experiments based on large scale bioinformatics outputs (ranking candidates, testing biological significance)
-Knowledge of the aging research field
-A strong understanding of genetics
-Experience with other model organisms especially mammalian systems

Application Process:
Interested applicants should email a (1) cover letter, (2) curriculum vitae, and (3) the names and contact information for three references directly to jeremy_vanraamsdonk@hms.harvard.edu.

 

Church Lab at Harvard Medical School

New Postdoc Position posted 12/7/18:

We are a seeking a postdoctoral research fellow for a project in which we are developing high throughput methods for identification of protein interaction partners. These methods will be used to identify targets of peptide toxins. This project is funded under an effort to develop experimental DNA biosecurity methodologies. The appointment will exist as a joint appointment in the Church Lab at Harvard Medical School and the Dong Lab at Boston Children’s Hospital. The Church Lab has broad expertise in biotechnology and the Don Lab has deep expertise in the identification and characterization of protein toxins. We seek to fill the position as soon as possible with the correct fit.

Applicants must have a PhD or equivalent in molecular biology, chemical biology, microbiology, or biotechnology. Additional expertise and research experience in the areas of chemistry and bioinformatics is also highly desirable, but not required. Experience with NGS, mass spectrometry, and/or CRISPR genome editing is also desired. Interested applicants should email their CV and cover letter to: gchurch@genetics.med.harvard.edu & donglab@childrens.harvard.edu. Please reference “Postdoc for Church/Dong Lab” in the subject line of your email.

 

Two different positions posted (as of 4/13/18)

1.
Exciting postdoctoral fellow opportunity in the Church lab: Computational biology for ancient DNA editing job description

The Church lab has a funded opportunity for a postdoctoral scientist to further the development of the lab’s efforts for mammoth de-extinction and also aging research. The scientist in this position will be responsible for devising and optimizing sample preparation and sequencing library generation protocols and acquiring, validating, and analyzing DNA and RNA sequencing data from edited samples for the mammoth and aging research. Beyond these specific projects working in collaboration with two postdoctoral fellows in the lab, this scientist is expected to become a leading resource within the Church lab on analyzing ‘omics’ methods generally, who will consult and collaborate with others both within and outside of the lab on best ways of conducting and developing these exciting projects. The ideal candidate will have a demonstrated record of scientific rigor, ingenuity, and peer-reviewed publications, and be well-organized, self-motivated, and able to work well both in teams and alone. Candidates should have a strong background and experience in computational aspects of high-throughput DNA and RNA sequencing, use of high-throughput omics data in the context of systems and/or synthetic biology projects, and a strong understanding of statistics. Experimental background is a plus but not required. Good oral and written communication skills are required.

Please include the following information in your cover letter:

Are you legally authorized to work in the United States? Will you now or in the future require sponsorship for employment visa status?

Email your cover letter and CV with the following reference code in the subject line: Ref# DNA2018_Apr To: Eriona_Hysolli@hms.harvard.edu

Have any references sent directly from your referee to the same email address.

2.
The Church lab has funded opportunities for postdoctoral scientists to advance two synthetic biology projects funded by the U.S. Department of Energy's (DOE) biofuel generation programs.  To be used in the subject line when applying: DOE2018_APR 

Postdoctoral Fellow in Translation Engineering
The aim of one project is to conduct large-scale reengineering of the protein translation systems of E. coli strains whose genomes have been recoded so that one or more codons are unused, so that proteins containing multiple, distinct non-standard amino acids (NSAAs) (including D-amino acids) can be efficiently generated. The scientist in this position will work with others in the lab to devise and implement ambitious strategies for developing, testing, demonstrating, and optimizing integrated sets of translation system components (such as tRNAs, amino-acyl tRNA synthetases, ribosomal proteins, rRNAs, and associated translation factors), that will operate together or in parallel in support of this goal.

Postdoctoral Fellow in Biosensor Development
The aim of the second project is use synthetic biology, structural biology, and protein engineering methods to alter existing proteins, or de novo design new ones, that respond efficiently and specifically in microbes to small molecules of potential importance or interest to DOE’s program. The scientist in this position will leverage high-throughput computational biology, synthesis, and sequencing methods to generate and screen diverse libraries of biosensor proteins and optimize their products, in ways that either further advance techniques already developed or demonstrated by the lab or work towards new ones, and will also consider how NSAAs might be used in protein redesign.

The scientists in either of these positions are expected to become leading resources within the Church lab on the general techniques and biology relevant to their projects, who will consult and work with others both within and outside of the lab on the best ways of leveraging these methods in related applications or towards other goals. The ideal candidates will have demonstrated records of scientific rigor, ingenuity, and peer-reviewed publications, and will be well-organized, self-motivated, and to work well both in teams and alone. Candidates should be fast learners who have prior experience with sets of high throughput experimental and computational methods that are relevant to the positions for which they apply, should be familiar with high-throughput omics data analysis techniques, and should have a strong understanding of statistics. Experience with technology development of new omics capabilities is highly desirable. Excellent oral and written communication skills are required.

Please answer the following questions below in your cover letter and include your CV and recommendations via email to church_lab_admin@hms.harvard.edu
1. Are you legally authorized to work in the United States? Will you now or in the future require sponsorship for employment visa status?
2. What is your ideal scenario for a postdoc and beyond?
Please to be sure to use this subject line when applying: DOE2018_APR

Yankner Laboratory at Harvard Medical School
Positions available to study gene regulation, epigenetics and the molecular biology of aging and neurodegenerative diseases.  Projects focus on iPS cells, C. elegans, animal models and the biology of genes involved in aging and Alzheimer's disease. For reference see: Nature 507:448, 2014, J. Cell Biol. 203:457, 2013, Mol. Cell 40:333, 2010, Nature 464:529, 2010, Nature 429:883, 2004. Experience in molecular biology is required.

Send CV, a brief description of research experience and names of 3 references to: Dr. Bruce Yankner by email to aharwick@genetics.med.harvard.edu


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GLOBAL HEALTH AND SOCIAL MEDICINE

Global Health Equity Research Fellowship
The Department of Global Health and Social Medicine is seeking a post-doctoral fellow for the two-year Global Health Equity (GHE) Research Fellowship.* The Fellow will join the Harvard Medical School Global Health Research Core, directed by Professor Megan Murray, and will be based at a Partners In Health-supported site in Rwanda joining a multidisciplinary team of practitioners, program managers, policy makers, and researchers. During the fellowship, the fellow will conduct high quality research on health needs and program implementation and support a broader research capacity building program and the mentoring of junior researchers in research methods and results dissemination.

Implementation, operational, and scientific research is a principal mission of the HMS Global Health Research Core and Partners In Health. In 2012, Partners In Health-Rwanda, with the support of the Research Core, launched a comprehensive research capacity building program with the aim to cultivate a culture of research and develop technical skills and research leadership at Global Health Delivery Partnership-supported sites. The research spans a variety of health topics aimed at improving service delivery and health outcomes in Rwanda and in other low and middle income countries. Priority research areas for Partners In Health-Rwanda include women’s health, oncology, non-communicable diseases, HIV, maternal and child health, mental health, nutrition, and health systems strengthening. The GHE Research Fellow will develop research within a priority research area(s) and support research capacity building within this topic area.

Successful candidates will have recently completed the PhD (or equivalent) in public health, epidemiology, biostatistics, global health, or a related field. Individuals with clinical training (MD, NP, etc.) with demonstrated research training and experience also would be considered. Applicants should have 1) strong quantitative skills, 2) strong scientific writing and communication skills, and 3) previous teaching experience. Experience living/working in a cross-cultural environment and French fluency are preferred.
* The appointee would be employed by Harvard Global Support Services.


Anticipated start date: June 1, 2019 or as soon as possible
Salary range: US$50-55,000
Relocation costs are negotiable

Interested applicants should send their cover letter, CV, and contact information for three references in one PDF named “GHE-fellow-application-2019_[your last name, first initial]” to Rebecca Grow (email: rgrow@hms.harvard.edu). Application deadline: February 15, 2019

For additional information see:

HMS Global Health Research Core   (https://hms.harvard.edu/departments/global-health-research-core)
Global Health Delivery Partnership   (http://ghsm.hms.harvard.edu/about-us/partners)
Partners In Health   (https://www.pih.org/)

 

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HARVARD CATALYST

No positions currently listed.

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HEALTH CARE POLICY

No positions currently listed.

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IMMUNOLOGY

No positions currently listed.

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MICROBIOLOGY

Abraham Laboratory at Harvard Medical School
The Abraham laboratory in the Department of Microbiology at Harvard Medical School is seeking a highly motivated postdoctoral candidate with expertise in virology, molecular biology, and genome editing (CRISPR/Cas9). Our laboratory uses a wide-array of approaches to study how emerging pathogens interact with cells and immune systems of their hosts. The project will involve performing genetic screens to probe host-pathogen interactions. Strong candidates would have extensive experience with mammalian tissue culture and viral infectivity assays. Publications from our laboratory include: Mahmutovic S et al. Cell Host & Microbe 2015, and Clark LE et al. Nature Communications 2018.

Interested applicants should send a CV, including the names/email addresses of 2-3 references, to abraham@crystal.harvard.edu  (11.26.18)


Gehrke Laboratory at Harvard Medical School
The Gehrke laboratory is looking for a U.S. citizen postdoc to join a team that is studying neurotropic virus infections using 2D and 3D tissue models.  Applicants must have Ph.D. or M.D. degree with a background in virology and familiarity with molecular techniques.  The work will involve BSL3 pathogens. Available immediately. Please send inquiries to lee_gehrke@hms.harvard.edu. (6.2.17)

Nibert Lab
August 20, 2018 - Postdoc Position available immediately

Available position: Postdoctoral research associate
Location: Nibert lab, Department of Microbiology, HMS (NRB-939, 77 Ave Louis Pasteur)

Project: Molecular biology of Trichomonas vaginalis viruses, including genomic characterizations, dissection of packaging/replication/translation signals, and structure-function studies of virus particles and proteins
Job Responsibilities include: Working collaboratively to design experiments, perform experiments, analyze data, present data to academic colleagues, prepare manuscripts.

Please email a CV, cover letter, and names of at least two references to:
Max Nibert, Professor of Microbiology
mnibert@hms.harvard.edu


Yang Laboratory at Harvard Medical School
The Yang Lab has two immediate openings for postdoctoral fellows to play a vital role in the discovery and optimization of small molecule antivirals. Must have established expertise in protein expression (microbial, insect, and mammalian cells) and purification as well as with a variety of biophysical and biochemical methods for characterizing protein-small molecule interactions. Experience with high-throughput screening and/or molecular virology techniques is desired but may be substituted with a willingness and aptitude to learn. Must be willing to work with viral pathogens in a BSL2+ lab.

You will be working within a multidisciplinary group of structural biologists, medicinal chemists, biochemists, and virologists. This position requires excellent communication and organizational skills, and a willingness to help train and mentor more junior members on the research team. This is an excellent opportunity for a post-doctoral fellow to acquire experience relevant to future employment in industry while still operating within an academic environment. This position is funded by an NIH grant through 2018. Applicants are expected to make a 3 year commitment.

Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to:
Priscilla L. Yang., Ph.D.
Department of Microbiology and Immunobiology
Harvard Medical School
Email: Priscilla_yang@hms.harvard.edu


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NEUROBIOLOGY

Pecot Lab at Harvard Medical School (posted 3.13.19)
The Pecot Lab in the Department of Neurobiology at Harvard Medical School is seeking postdoctoral researchers interested in studying the molecular basis of precise neural connectivity. The goal of our research is to identify general molecular and cellular principles that underlie how neural networks are assembled. We address this at the level of identified cell types and synapses in the fly visual system. We are interested in the molecules that underlie how neurons distinguish each other and form synapses with appropriate partners, and in determining the gene regulatory networks that give rise to the expression of these genes in specific cell types. We employ a diverse experimental approach, involving molecular genetics, transcriptome profiling, genomics, confocal and superresolution microscopy, calcium imaging, and electron microscopy. Training in neuroscience or fly genetics is welcome but not necessary. We offer a supportive, collaborative and creative environment. 

Please email a cover letter, a curriculum vitae, and names & email addresses of three references to:
Matthew Y. Pecot, Ph.D.
Department of Neurobiology
Harvard Medical School
Armenise 203
Boston, MA 02115
Email: matthew_pecot@hms.harvard.edu
Website: www.pecotlab.com

 

________________________________________

Born Lab (and Haefner Lab)  (posted 3.12.19)
TWO (EXP+THEORY) POSTDOCTORAL FELLOWSHIPS IN SYSTEMS NEUROSCIENCE
Perceptual decision-making in a probabilistic inference framework
The laboratories of Rick Born in the Dept. of Neurobiology at Harvard Medical School, and Ralf Haefner in the Dept. of Brain & Cognitive Science at University of Rochester, are seeking applications for two NIH-funded postdoctoral fellowships to study the role of top-down connections in conveying learned priors within a theoretical framework of perception as probabilistic inference. Specific projects will address the neural bases of multi-tasking and confirmation bias. Experimental techniques include population recordings from area V1 with and without cortical feedback inactivated by cooling V2/3. Data analysis techniques include applying latent-state inference methods. Theoretical work will involve generating empirically testable predictions using sampling-based and variational techniques applied to probabilistic models.
Link to full posting

The successful candidates will interact extensively with each other, both PIs and their labs. Please visit the lab web sites (Born Lab & Haefner Lab) to obtain more information on current interests and electronic versions of recent research papers. Preliminary results from a closely related project on learning can be found here.
The ideal candidate for the experimental position will have experience in one or more of the following areas: training nonhuman primates, extracellular electrophysiology, reversible inactivation of cortex, MATLAB programming. Candidates with a computational neuroscience background and an interest in visual processing will also be considered.

Candidates for the theoretical position should have strong quantitative and programming skills, ideally (but not necessarily) with experience in computational neuroscience and probabilistic modeling.

Salary will be commensurate with experience according to the current NIH scale. Please send curriculum vitae, statement of research interests, up to three reprints, and a minimum of two letters of recommendation to either richard_born@hms.harvard.edu or rhaefne2@ur.rochester.edu.

Harvard Medical School and University of Rochester are Affirmative Action/Equal Opportunity Employers. Applications from minorities and women are especially encouraged.

 

__________________________________________

Drugowitsch Lab at Harvard Medical School
We are looking for a highly creative and motivated postdoctoral fellow to work in the field of computational and systems neuroscience in the group of Jan Drugowitsch - Department of Neurobiology at Harvard Medical School. The group works on questions of decision-making and navigation under uncertainty, ranging from the level of neural populations to that of behavior. In the short term, the postdoctoral fellow is expected to design and analyze behavioral and neural models of decision-making that are gauged against data from human subjects, collected by the laboratory of Dr. Wyart at École Normale Supérieure, Paris. In the long term, close interaction and collaboration with other members of the department is anticipated.

Candidates should have a strong analytical background, such as in computational neuroscience, physics, mathematics, engineering, or related, and feature an interest in the role of computation in neural populations and in theoretical neuroscience in general. Experience or familiarity with related machine-learning fields is also desirable. Previous experience should include sufficient programming skills to run numerical simulations, Bayesian methods, and expertise in the analysis of dynamical systems.
The position starts in or after April 2018, and is funded for several years, with an initial one-year appointment and expectation of extension given satisfactory performance. Salary depends on experience and is at levels above the NIH scale. More info
HERE.
Candidates should send a single PDF file, consisting of a 1-page motivation letter, CV, and publication list to jan_drugowitsch@hms.harvard.edu. Furthermore, candidates should organize two letters of reference, to be sent to the same e-mail address. The position is open until filled (posted on this site: 2.22.18).

Gu Laboratory at Harvard Medical School
A postdoctoral position is available to study the coordinate development of nervous and vascular systems using mouse genetics, biochemistry, imaging, and in vitro assays. Applicants should be accomplished in biochemistry, molecular biology, cell biology. Experience in the biochemical and functional characterization of proteins in the signaling pathways would be especially desirable.
 Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to:
 Chenghua Gu, D.V.M., & Ph.D
Department of Neurobiology
Harvard Medical School
Email: chenghua_gu@hms.harvard.edu
HMS Dept. of Neurobiology Website: http://neuro.med.harvard.edu/

Kaeser Lab at Harvard Medical School
The Kaeser lab in the Department of Neurobiology at Harvard Medical School is seeking postdoctoral fellows to study architecture, functions and diversity of presynaptic neurotransmitter release sites. We are deeply invested into dissecting the molecular machines called active zones that mediate the release of fast neurotransmitters, for example glutamate, and of neuromodulators, for example dopamine. We further study how active zone composition is modulated by activity and how cell-type or synapse specific active zone architecture modulates circuit function. We use a variety of techniques (mouse genetics, protein biochemistry, electrophysiology, optogenetics, functional imaging, superresolution and electron microscopy) to study how active zones assemble and operate. Training in neuroscience and experience in any of these techniques is desirable, but not mandatory. We offer an excellent environment to use a multidisciplinary approach for addressing fundamental secretory mechanisms in a collaborative atmosphere.
Please email a cover letter, a curriculum vitae, and names & email addresses of three references to:
Dr. Pascal Kaeser
Department of Neurobiology
Harvard Medical School
220 Longwood Ave.
Armenise 305
Boston, MA 02115

Email: kaeser@hms.harvard.edu
Website: http://kaeser.hms.harvard.edu

Pecot Lab at Harvard Medical School
The Pecot Lab in the Department of Neurobiology at Harvard Medical School is seeking postdoctoral researchers interested in studying the molecular basis of precise neural connectivity. The goal of our research is to identify general molecular and cellular principles that underlie how neural networks are assembled. We address this at the level of identified cell types and synapses in the fly visual system. We are interested in the molecules that underlie how neurons distinguish each other and form synapses with appropriate partners, and in determining the gene regulatory networks that give rise to the expression of these genes in specific cell types. We employ a diverse experimental approach, involving molecular genetics, transcriptome profiling, genomics, confocal and superresolution microscopy, calcium imaging, and electron microscopy. Training in neuroscience or fly genetics is welcome but not necessary. We offer a supportive, collaborative and creative environment. 
Please email a cover letter, a curriculum vitae, and names & email addresses of three references to:
Matthew Y. Pecot, Ph.D.
Department of Neurobiology
Harvard Medical School
Armenise 203
Boston, MA 02115
Email:
matthew_pecot@hms.harvard.edu
Website: www.pecotlab.com


Weitz Laboratory at Harvard Medical School
A postdoctoral position is available for cryo-EM analysis of protein complexes comprising the core of the mammalian circadian clock, a molecular oscillator present in all or nearly all cells that drives daily rhythms of physiology and behavior. Applicants should be accomplished in biochemistry and structural biology. Expertise in cryo-EM structure determination would be especially desirable. We have made progress in single-particle analysis of native circadian clock complexes purified from mouse tissues, and we aim to obtain high-resolution structures.
Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to:
Charles J. Weitz, M.D., Ph.D.
Department of Neurobiology
Harvard Medical School
Email: cweitz@hms.harvard.edu

Some recent papers:
1. Duong HA, Robles MS, Knutti K, Weitz CJ. A molecular mechanism for circadian clock negative feedback. Science 2011; 332: 1436-9.
2. Padmanabhan K, Robles MS, Westerling T, Weitz CJ. Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex. Science 2012; 337: 599-602.
3. Kim JY, Kwak PB, Weitz CJ. Specificity in circadian clock feedback from targeted reconstitution of the NuRD co-repressor. Molecular Cell 2014; 56: 738-748.
4. Tamayo AG, Duong HA, Robles MS, Mann M, Weitz CJ. Histone mono-ubiquitination by Clock–Bmal1 complex marks Per1 and Per2 genes for circadian feedback. Nature Structural & Molecular Biology 2015; 22: 759-766.
5. Aryal RP, Kwak PB, Tamayo AG, Chiu PL, Walz T, Weitz CJ. Macromolecular assemblies of the mammalian circadian clock. Molecular Cell 2017 (in press).


Goodrich Laboratory at Harvard Medical School
The Goodrich lab is seeking a postdoctoral fellow to study the development of neural circuits in the auditory system. We use mouse genetics to understand how changes in the circuits of the inner ear affect an animal’s ability to detect and perceive sound. Projects employ a variety of techniques, including biochemical analysis of novel proteins, in vitro culturing of inner ear neurons, imaging of single cells during auditory circuit assembly, and gene expression profiling of wild-type and mutant cells. No experience with the auditory system is required, but a familiarity with neuroscience or mouse genetics is a plus. Individuals with expertise in cell biology, imaging, microarrays, or signal transduction are particularly encouraged to apply.

Please send a cover letter, CV, and three references to:
Dr. Lisa Goodrich

Dept of Neurobiology, Harvard Medical School
220 Longwood Avenue
Goldenson 442
Boston, MA 02115
Email: Lisa_Goodrich@hms.harvard.edu

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SYSTEMS BIOLOGY


Higgins Laboratory at Harvard Medical School (updated posting 3.12.19)
Research Area:  Mechanistic Mathematical Modeling of Human Disease Processes with Clinical Data

Description:  The Higgins Laboratory (Department of Systems Biology) has an opening for a postdoctoral fellow to study in vivo human blood cell population dynamics, characterizing rates of immunologic and hematologic processes and their fluctuations during times of health as well as when perturbed by diseases including infection, cancer, and diabetes, both acutely and chronically. 

Qualified applicants will have extensive knowledge of and interest in human pathophysiology, dynamical systems, numerical methods, and good software engineering practices.  For example, strong candidates would be able to compare and contrast the following:  finite elements and finite differences, lymphocyte and myelocyte, quicksort and bubble sort.  Applicants should have a Ph.D. and/or M.D. degree or be in the final year of their doctoral studies, and at least a strong undergraduate background in math, computer science, and engineering.  Interested individuals should apply by submitting an updated CV, complete contact information for three references, and a cover letter describing past research experience, research interests, and career goals.

The Marks lab, Department of Systems Biology -  Assistant Research Director  (posted 3.8.19)
Job Description:
The Marks lab in the Department of Systems Biology at Harvard Medical School is recruiting an Assistant Research Director to work closely with the PI Debora Marks in supporting exciting new projects that develop machine-learning methods for applications in neurodegeneration, synthetic biology and drug design. The individual in this role will take the lead in project management, partnering with Dr. Marks to recruit and mentor graduate students and postdoctoral fellows, manage the collaborative projects, assist with the writing of grants, progress reports, and research papers.
Preferred Qualifications:
The successful candidate will have a PhD and is likely to have research experience in experimental biology or computational biology. The position requires a sophisticated understanding of molecular biology, and superb organizational skills. Familiarity with the development and maintenance of software and servers and coding experience are advantageous but not strictly required. Strong communication and writing skills are vital, and finalists may be required to demonstrate their writing and/or editing skills. To apply, please submit a cover letter and CV . In the Subject line of your email, please write: Assistant Lab Research Director. Please note that this position is classified in the Harvard system as a Research Associate.
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.
Job Type: Full-time
Education: Doctorate (Preferred)
Work authorization: United States (Required)
https://www.indeed.com/jobs?q=lab%20director&l=Boston%2C%20MA&advn=3746778855682588&vjk=f348a094a2439ce9

Associate Lab Director, Harvard Medical School, Paulsson Lab (posted 3.8.19)
Job Description:

The Paulsson lab in the Department of Systems Biology at Harvard Medical School is recruiting an Associate Research Director. This position works in partnership with the PI (Johan Paulsson) to lead several challenging and exciting projects at the interface of bacterial physiology and biophysics. We are looking for a broadly trained bacterial geneticist excited about fundamental mechanisms as well as method development. The position involves three major activities: making intellectual contributions on projects related to bacterial genetics, physiology and evolution; managing a small team of technical staff to engineer proteins and circuits at the level of deep mutational scans and complex synthetic circuits; and serving as a scientific project manager for grant submissions and reports. The Associate Lab Director will be a key intellectual partner and collaborator for many lab members, and recognized as an author on publications and patents whenever appropriate.
Preferred Qualifications:
A PhD in a biology-related field is required, with extensive and in-depth experience in bacterial genetics and physiology, preferably E. coli. Postdoctoral experience is preferred. Scientific rigor and attention to detail are essential, and creativity and an ability to see the bigger picture are a great plus. This is a high-energy and highly interactive position where excellent personal skills, including a sense of humor, are vital. Strong writing skills are also key. The academic title for this position is Research Associate.To apply, please submit a cover letter and CV. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.
Job Type: Full-time
Education: Doctorate (Preferred)
Work authorization: United States (Required)https://www.indeed.com/jobs?q=associate lab director&l=Boston%2C MA&advn=3746778855682588&vjk=a55cce0a334a5768 

Paulsson Lab - Research Specialist - Harvard Medical School (posted 9.11.18)
Job Description: The Paulsson lab in the Department of Systems Biology at Harvard Medical School is recruiting a Research Specialist to work in partnership with the PI (Johan Paulsson) to manage a wide range of challenging and exciting projects at the interface of bacterial physiology and biophysics. We are looking for a broadly trained bacterial geneticist excited about fundamental mechanisms as well as method development. The position involves three major activities: intellectual contributions on a wide range of projects related to bacterial genetics, physiology and evolution; managing a small team of technical staff to engineer proteins and circuits at the level of deep mutational scans and complex synthetic circuits; and serving as a scientific project manager for grant submissions and reports. The Research Specialist is expected to be a key intellectual partner and collaborator for many lab members, and will be recognized as an author on publications and patents whenever appropriate. 

Preferred Qualifications: 
A PhD in a biology-related field is required, with extensive and in-depth experiences in bacterial genetics and physiology, preferably E. coli but experience with other bacterial  species would also be valued. Scientific rigor and great attention to detail are essential, and creativity and an ability to see the bigger picture are a great plus. This is a high-energy and highly interactive position, where so excellent personal skills, including a sense of humor, are vital. SVery strong writing skills are also key. To apply, please submit a cover letter and CV to Johan_Paulsson_Office@hms.harvard.edu. Please note that this position is classified in the Harvard system as a Research Associate.
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.


Mootha Laboratory at Harvard Medical School
The Mootha laboratory (Department of Systems Biology) has a funded opportunity for a postdoctoral scientist in computational genetics.
The laboratory focuses on mitochondrial biology and disease and consists of a lively group of computational biologists, experimental biochemists, and physician-scientists. We are currently seeking a postdoctoral scientist to work at the interface of human genetics and systems biology, with the goal of analyzing very large scale human genome sequence datasets using network models of mitochondria derived from cellular and biochemical studies, to address questions spanning disease, epistasis, and evolution.
 Applicants should possess a Ph.D. and/or M.D. degree in computational biology, preferably with a proven track record in computational genetics and analysis of next-generation sequencing data. Interested individuals should send a cover letter, curriculum vitae, and the names/phone numbers of three people who could provide letters of reference by email to vamsi@hms.harvard.edu.
 For additional information please visit our webpage: http://mootha.hms.harvard.edu/


Fontana Laboratory at Harvard Medical School
The Fontana Laboratory is seeking two outstanding post-docs to accomplish in collaboration with other groups a prototype end-to-end pipeline that extracts detailed mechanistic information about protein-protein interactions from databases and text, assembles such information into executable reference models for the purpose of understanding their dynamical behavior and assessing the current knowledge base in specific cell signaling systems. A can-do attitude, hacker soul, originality coupled to team spirit, fearlessness, and dedicated work ethic are necessary characteristics. Pay is commensurate to experience.
 Position 1: Computer science / AI / bioinformatics / databases
The ideal candidate combines an interest, and possibly expertise, in Artificial Intelligence (text extraction, natural language processing, reasoning) with bioinformatic skills. The individual will collaborate with other groups in excavating information about molecular interactions from extant databases and text; organizing such information for translation into a formal and executable format from which models of cellular signaling are constructed. The candidate should be capable of scripting in Python or Perl, be familiar with procedural and functional programming paradigms (e.g. Java or similar and OCaml or similar) and have database experience.
Position 2: Modeler / cellular signaling / cancer pathways
The ideal candidate is a computational biologist with experience in modeling dynamical systems. The individual is a skilled programmer (C, C++ or similar, experience with OCaml a plus) who will work with Kappa, a formal agent-based modeling language (https://github.com/jkrivine/KaSim) and associated tools. Ease with formal / mathematical thinking is required. A sound instinct for molecular biology coupled to a physics mindset is highly desirable. The position functions as a modeling keystone within an ambitious project seeking to build large dynamic “reference models" of cell signaling networks involved in RAS-related cancers. Models of such networks are assembled using mechanistic knowledge extracted from databases and texts in collaboration with outside groups providing pertinent expertise.

To apply, send CV and a covering letter to Walter Fontana: walter@hms.harvard.edu.


Megason Laboratory at Harvard Medical School
A postdoctoral research fellow position is available in the Megason lab in the Department of Systems Biology at Harvard Medical School in the areas of embryology, genetics, imaging, and systems biology. The Megason Lab has initiated a project to generate a Digital Fish which is a computer recreation of how the genome is executed to turn an egg into an embryo. We combine novel imaging technologies called in toto imaging to extract quantitative molecular and cellular data from living, developing zebrafish embryos for use in modeling. In toto imaging uses confocal and 2-photon microscopy to image and track every cell in developmental processes to reconstruct complete digital cell lineages. We also are developing a novel genetic approach called FlipTraps which generate endogenously expressed fluorescent fusion proteins and Cre condtional alleles. We combine these approaches to generate quantitative models of how systems of molecules program cells and systems of cells program tissues. Additionally, we are particularly interested in applicants with experience, expertise, and interest in home built 2-photon microscopy systems. For more information please contact Sean Megason (megason@hms.harvard.edu) or visit our website www.digitalfish.org.

A cover letter detailing your research motivations and a curriculum vitae should be sent by email to the above address together with the names of three referees with contact information.

Sean Megason, PhD
Department of Systems Biology
Harvard Medical School
200 Longwood Avenue, WAB 536
Boston, MA 02115


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HARVARD SCHOOL OF DENTAL MEDICINE 

YANG LAB

A post-doctoral position is available immediately in the Yang lab based in the Department of Developmental Biology at the Harvard School of Dental Medicine.

The laboratory of Dr. Yingzi Yang has a longstanding and intense interest in defining the functional mechanisms of Wnt, Hippo, and Hedgehog signaling pathways in development and disease pathogenesis including cancer. One of our recent projects is understanding metabolism and tumor microenvironment in liver hepatocyte carcinoma (HCC) progression. This study is being pursued through the generation and analyses of genetically engineered mice, in vitro studies with cell biology and biochemistry approaches as well as corroborative studies using human specimens. This work also involves cutting-edge imaging techniques and liver tumorigenesis in vitro and in vivo models. Protein chemistry and engineering is a plus. The position is funded by NCI.

The candidate should have a PhD degree in biomedical sciences with less than 3 years of postdoctoral experience and a proven record of scientific productivity. Basic skills in molecular, genetic and cell biology are required. Duties and responsibilities of the successful candidate will include:

• strong abilities to work independently and with self-initiative;

• abilities to vigorously pursue scientific projects, both conceptually and experimentally, with pro-active thinking and action;

• collaboration with other research staff, supervision and training of lab members;

• writing and editing of manuscripts, research presentations at departmental seminars and scientific meetings.

Salary will follow NIH and university guidelines.
To apply, please send a brief statement of research interests, CV and contact information of three references to:
Yingzi Yang, PhD
Yingzi_yang@hsdm.harvard.edu
(posted 6/7/18)

IONESCU LAB
A postdoctoral fellow position (or visiting research scholar) is available in the laboratory of Dr. Andreia Ionescu at Harvard School of Dental Medicine in Boston. We are seeking Postdoctoral candidates who are independent, highly motivated and career-oriented to work on NIH-funded projects in the areas of skeletal development and disease. The successful candidate will be involved in cartilage and bone regeneration projects.

Potential candidates should have experience working with histology, molecular biology, tissue culture techniques, and mouse models. A strong background in stem cell biology will receive higher priority. Expertise in Rna-seq and ChIP-seq is desirable. Prior experience with Laser Capture Microscopy is a plus.

To apply, send your CV and email addresses of three references to: 
Dr. Andreia Ionescu, PhD
Dept. of Developmental Biology, Harvard School of Dental Medicine
188 Longwood Ave, Boston, MA 02115. Tel: 617-432-5912
Email:
Andreia_Ionescu@hms.harvard.edu
(posted 10.23.18)

 

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WYSS INSTITUTE (Department job site)

Postdoctoral Fellows Positions at the Wyss Institute for Biologically Inspired Engineering
The Wyss (pronounced "Veese") Institute for Biologically Inspired Engineering uses Nature's design principles to develop bioinspired materials and devices that will transform medicine and create a more sustainable world.
 Working as an alliance among Harvard's Schools of Medicine, Engineering, and Arts & Sciences, and in partnership with Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Dana Farber Cancer Institute, Massachusetts General Hospital, the University of Massachusetts Medical School, Spaulding Rehabilitation Hospital, Tufts University, and Boston University, the Institute crosses disciplinary and institutional barriers to engage in high-risk research that leads to transformative technological breakthroughs.
 
Visit the Wyss Institute's website to find out positions available: http://wyss.harvard.edu/viewpage/191/postdoctoral-positions

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