- Please note, these job postings are a courtesy to the HMS Postdoc community. Send any and all inquiries about job opportunities below to the listing organization, company or individual and not to the OPF. Employers: If you would like us to post your job opportunity, submit HERE.-
Preceptor in Stem Cell and Regenerative Biology, Harvard University, Faculty of Arts and Sciences
The Harvard Department of Stem Cell and Regenerative Biology (HSCRB) is the first and only cross-school academic department in both the Harvard Faculty of Arts and Sciences and Harvard Medical School. As a result, the educational mission spans undergraduate, graduate, and medical communities on both the Cambridge and Longwood campuses, as well as the Harvard-affiliated hospitals. Pedagogically, the curriculum emphasis hands-on laboratory experience and inquiry-based learning.
Duties and Responsibilities: Works as a preceptor for undergraduate courses in HSCRB, with responsibility for SCRB 10 (Human Developmental and Regenerative Biology) and two advanced laboratory courses (SCRB 15 – CRISPR Cas9: Precision Genetics and Gene Therapy; SCRB 50 – a new molecular biology lab course to launch spring 2020). Reports to the Associate Director of Education in HSCRB, in close collaboration with the faculty instructors of the courses. This position is for one year, with reappointment possible on a yearly basis for up to eight years (within the eligibility guidelines of the FAS), contingent on performance, curricular need, position availability, and divisional dean authorization. More info and how to apply.
Allergan - Senior Researcher, Research and External Science & Innovation, location is Cambridge, MA.
We are seeking two Ph.D.s and or M.D.s, ideally with post-doctoral experience in an innovative area of neuroscience that complements internal capabilities. This is a unique opportunity within a different kind of pharma company.
Position Summary: The Research and External Science and & Innovation (RESI) team is responsible for identifying, evaluating, and championing the science of external (and internal) projects and partnership opportunities across our therapeutic areas from pre-clinical through development. Our business model is dependent on external sourcing of pipeline opportunities and as such the group has a unique ability to impact the success and future direction of the company. The RESI team evaluates strategic areas of interest, considers creative ways to progress programs through partnerships, and provides scientific leadership to partnered and internal projects. Like a venture capital firm, we evaluate the external landscape and, with our colleagues across the R&D organization, recommend where to invest for our pipeline. A few recent examples include our acquisition and spin of Naurex/Aptinyx for novel anti-depressants, our acquisition of CGRP compounds from Merck, our CRISPR partnership with Editas in ophthalmology, and our partnership with Heptares for novel muscarinic molecules.
The successful candidate will bring neuroscience expertise in an emerging area of science to complement internal capabilities while welcoming the challenge of new areas. While contributing to these activities, the successful candidate will learn drug discovery and development, be challenged with new areas of science, be exposure to a diversity of small biotechs, investment models and venture capital firms.
Norvatis - BioMedical Research, Innovation Fellow. The call for applications is open until May 1st.
Novatis is committed to training the next generation of scientific leaders. The Novartis Innovation Postdoctoral Fellowship offers aspiring drug hunters a unique opportunity to join our teams at the Novartis Institutes for BioMedical Research (NIBR), the innovation engine of Novartis. Mentored by NIBR scientific leaders, Innovation Fellows will gain first-hand experience in the design and development of breakthrough therapies and innovative technologies. We are looking for Innovation Fellows who will bring their scientific creativity and natural curiosity to tackle important therapeutic challenges. Join us as we reimagine medicine together.
- Program duration: 2-3 years
- Boot camp: Innovation Fellows will attend a fully immersive boot camp covering the fundamentals of drug discovery and development
- Mentorship & access to technology: Innovation Fellows will have access to NIBR state-of-the-art technology platforms and be mentored by selected NIBR scientific leaders
- Rotations: Innovation Fellows will benefit from a tailored rotation schedule in both scientific and business-related disciplines
- Fireside chats with local leaders in academia and industry
- Community: Innovation Fellows will join Discovery Fellows in our vibrant postdoctoral community with dedicated events, including our annual Research Day Symposium
Who are the Innovation Fellows?
- Early-career scientists, within 3 years of receiving their MD and/or PhD (students in their last 4 months of graduation are eligible to apply)
- All scientific and technical disciplines welcome (e.g. biology, biophysics, chemical biology, chemistry, computational and data sciences, engineering, and more)
- Strong publication track record or other scientific achievements
- Entrepreneurial mindset and boundless curiosity
- Dedicated to translating scientific discoveries into medicines that improve human health
How to Apply
- Please submit your CV and cover letter by May 1, 2019 for consideration. Include a potential area of unmet medical need where you believe you could make an impact.
- All applications will be evaluated by a review team comprised of discipline experts and drug hunters from NIBR.
- Candidates selected as finalists will be invited to our Cambridge, MA campus for an all-day interview in June 2019. New Innovation Fellows will start in September 2019 at our Cambridge site.
Apply (https://www.novartis.com/careers/career-search/job-details/262871BR) (3.14.19(
Brigham & Women’s Hospital Postdoctoral position – The Nasr Lab
One postdoctoral position is available immediately in the laboratory of Dr. Nasr for a highly motivated individual interested in using cryo-EM for the structural studies of viral membrane proteins in nanodiscs. The project will employ a rang of techniques including: membrane protein expression and purification, mammalian cell culture; and nanodisc engineering. Experience in cryo-EM is preferred but not required.
Applicant should have a recent Ph.D (or anticipate to graduate soon) in a biological field.
The Nasr lab is in the Division of Engineering in Medicine and Renal at Brigham & Women’s Hospital, part of the Harvard Medical School research community at the Longwood Medical Area in Boston, MA. Applicant should email a cover letter and a CV, and arrange for 3 letters of references to be emailed to Dr Nasr ; firstname.lastname@example.org. Please be sure to indicate in your cover letter if you would require visa sponsorship. (3.11.19)
Associate Lab Director, Harvard Medical School, Paulsson Lab (posted 3.8.19)
The Paulsson lab in the Department of Systems Biology at Harvard Medical School is recruiting an Associate Research Director. This position works in partnership with the PI (Johan Paulsson) to lead several challenging and exciting projects at the interface of bacterial physiology and biophysics. We are looking for a broadly trained bacterial geneticist excited about fundamental mechanisms as well as method development. The position involves three major activities: making intellectual contributions on projects related to bacterial genetics, physiology and evolution; managing a small team of technical staff to engineer proteins and circuits at the level of deep mutational scans and complex synthetic circuits; and serving as a scientific project manager for grant submissions and reports. The Associate Lab Director will be a key intellectual partner and collaborator for many lab members, and recognized as an author on publications and patents whenever appropriate.
A PhD in a biology-related field is required, with extensive and in-depth experience in bacterial genetics and physiology, preferably E. coli. Postdoctoral experience is preferred. Scientific rigor and attention to detail are essential, and creativity and an ability to see the bigger picture are a great plus. This is a high-energy and highly interactive position where excellent personal skills, including a sense of humor, are vital. Strong writing skills are also key. The academic title for this position is Research Associate.To apply, please submit a cover letter and CV. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.
Job Type: Full-time
Education: Doctorate (Preferred)
Work authorization: United States (Required)
https://www.indeed.com/jobs?q=associate lab director&l=Boston%2C MA&advn=3746778855682588&vjk=a55cce0a334a5768
Assistant Research Director - The Marks lab, Department of Systems Biology, Harvard Medical School
Job Description: The Marks lab in the Department of Systems Biology at Harvard Medical School is recruiting an Assistant Research Director to work closely with the PI Debora Marks in supporting exciting new projects that develop machine-learning methods for applications in neurodegeneration, synthetic biology and drug design. The individual in this role will take the lead in project management, partnering with Dr. Marks to recruit and mentor graduate students and postdoctoral fellows, manage the collaborative projects, assist with the writing of grants, progress reports, and research papers.
Preferred Qualifications: The successful candidate will have a PhD and is likely to have research experience in experimental biology or computational biology. The position requires a sophisticated understanding of molecular biology, and superb organizational skills. Familiarity with the development and maintenance of software and servers and coding experience are advantageous but not strictly required. Strong communication and writing skills are vital, and finalists may be required to demonstrate their writing and/or editing skills. To apply, please submit a cover letter and CV . In the Subject line of your email, please write: Assistant Lab Research Director. Please note that this position is classified in the Harvard system as a Research Associate.
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.
Job Type: Full-time
Education: Doctorate (Preferred)
Work authorization: United States (Required)
Postdoctoral Research Position in Nephrology; Schlondorff Lab; Beth Israel Deaconess Medical Center/Harvard Medical School
A postdoctoral fellow position is available immediately in the laboratory of Johannes Schlondorff in the Division of Nephrology at Beth Israel Deaconess Medical Center, Boston, Massachusetts. The laboratory focuses on understanding glomerular podocytes and their role in kidney health and disease, with a particular interest in understanding the development and progression of proteinuric kidney diseases such as focal segmental glomerulosclerosis (FSGS). Several current projects focus on the role of TRPC6 channel mutations as a genetic cause of FSGS. The laboratory utilizes an array of techniques spanning protein biochemistry, cell biology, and genetically engineered mouse models in our efforts.
Candidates must have a Ph.D. or M.D./Ph.D. degree with a strong background in cell biology, cell signaling or animal models. Prior experience in the areas of kidney disease or TRP channel biology is highly desirable, but not necessary. Applicants should have a record of scientific achievement, be highly self-motivated, have a collaborative attitude, and have excellent organizational and communication skills.
EOE M/F/VET/DISABILITY/GENDER IDENTITY/SEXUAL ORIENTATION
To apply, please send a cover letter and CV to: email@example.com. (3.5.19)
Postdoctoral Research Fellow - Cancer Biology – Boston Children’s Hospital
Applications are currently being accepted for a postdoctoral fellow to join the laboratory of Khashayar Vakili at Boston Children’s Hospital/Harvard Medical School, Boston, Massachusetts. Our research focuses on elucidating the biology of liver cancer by analyzing signaling pathways of interest and developing in vitro and in vivo models with a focus on translational studies.
Qualified candidates must have a Ph.D. or M.D./Ph.D. degree with a strong background in advanced molecular biology, genetics, cell culture techniques, animal models, and cancer biology. Candidates must be self-motivated and possess strong communication/organizational skills along with a collaborative attitude. A strong record of scientific achievement is preferred. Salary will be determined based on the candidate’s experience and qualifications.
Please send cover letter, CV, and information for at least three references to:
Alex Lam at firstname.lastname@example.org (3.4.19)
Novartis: Associate Director Biostatistics - Biomarkers and Diagnostics within Pharmacometrics supporting Precision Medicine
Position can be based in either Cambridge, MA OR East Hanover, NJ.
The digital revolution is changing everything, especially in pharmaceuticals where we are collecting more data in our clinical trials than ever before. The question is, what do we do with it? At Novartis, we have over 20 years of untapped data waiting to be explored – thereby unlocking the secrets of the next breakthrough in innovative medicines for patients in need.
Description of the Role: The role is for a statistician in the Biomarker and Diagnostics Biostatistics (BDB) team. The team is responsible for bioinformatics and/or statistical activities in support of the Precision Medicine Drug (Rx) strategy and/or Companion Diagnostics (CDx) development within the Novartis Portfolio.
Full listing and to apply: https://www.novartis.com/careers/career-search/job-details/262194BR (2.26.19)
Novartis: Principal / Sr. Principal Scientific Computing - Multiple Locations
The digital revolution is changing everything, especially in pharmaceuticals where we are collecting more data in our clinical trials than ever before. The question is, what do we do with it? At Novartis, we have over 20 years of untapped data waiting to be explored – thereby unlocking the secrets of the next breakthrough in innovative medicines for patients in need. We are forming a new Scientific Computing and Consulting team that has the opportunity to reimagine how Novartis handles its clinical trial data by enabling the use of state of the art computing infrastructure, leveraging advanced visualization software solutions to dynamically explore our data in an interactive and collaborative manner.
- Drive the evaluation of business technology, scientific software, novel visualization tools, automated data provisioning pipelines and computation infrastructure improve, increase and enhance the quality and efficiency of Novartis drug development
- Provide a tight link with the IT organization. Uses influencing skills to ensure infrastructure and decisions made on IT systems meet the needs of the business, i.e. enable the business for the delivery of complex analytics
- Provide software tools and IT infrastructure solutions to enable Quantitative Sciences to work efficiently and effectively to deliver on tasks and make quantitative decisions to trial and or project level activities including dynamic solutions to proactively explore data and deeply characterize patients
- Incorporate evidence from sources of big data (e.g. genomics, biomarkers, digital technology, sensors, imaging and real world evidence)
- Supports the implementation, communication and education of innovative data interrogation / visualization methods
- Builds collaborative working relationships and communicates effectively with Quantitative Sciences partners along with clinical teams promote a greater mindset where associates may leverage each other’s skills in an open and transparent manner
Full details and to apply: https://www.novartis.com/careers/career-search/job-details/258285BR (2.26.19)
5AM Ventures 2019 Fellowship (July – December) at Boston office – Apply by March 15th
5AM Ventures is an early-stage biotech venture firm leveraging both venture creation (building biotech companies from scratch) and venture capital (leading syndicated venture capital deals) to bring new medicines to patients. Founded in 2002, the 5AM team takes a focused, hands-on approach to partnering with entrepreneurs. In addition to leading investments and contributing as board members of its portfolio companies, 5AM is directly involved in company strategy, management recruiting, business development and fundraising and often takes short-term operating roles. 5AM’s 4:59 initiative canvasses areas for science that may be ripe for building new companies. 5AM Ventures has offices in San Francisco, CA and Boston, MA, and approximately $1.5B under management.
The 5AM Ventures Fellowship provides an exclusive opportunity to gain experience in both venture creation and venture capital.
We are seeking a Fellow who can assist the 4:59 and 5AM teams with
1) reviewing new insights in prioritized areas of science to craft an investment thesis,
2) supporting scientific detailed diligence (e.g. research and talking to academics, KOLs), and
3) supporting new company formation activities with a focus on the scientific strategy.
Time commitment will be 20+ hours/ week, for 6 months. The firm is looking for an individual with strong scientific or medical background (MD and/or PhD) e.g. Post-docs, medical residents, or fellows.
To apply, please send an email with subject line “Boston Fellowship Application”, including your C.V., to Applications@5amVentures.com, by March 15th. (2.14.19)
Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center and Harvard Medical School, Whitney Laboratory
Description: A postdoctoral fellow position is available immediately in the Viral Dynamics Laboratory in the area of HIV cure and/or emerging diseases (https://www.whitneylaboratory.com). The fellow will be directly responsible for the conduct of experiments and analysis of data and will work together with other team members in drafting reports and manuscripts.
Requirements: A Ph.D. in immunology, or related field; Must have experience developing and validating complex multi-color flow cytometry panels, performing cell sorting, or performing functional immunology assays with primary cells. Evidence of productivity with first author publications in high impact journals is required. Experience working in BSL2/BSL3 conditions and with human or non-human primate samples is preferred, but not required..
EOE M/F/VET/DISABILITY/GENDER IDENTITY/SEXUAL ORIENTATION
To apply, please send CV to email@example.com (2.12.19)
Molecular Neuroscience Postdoctoral Fellow in Autism and Epilepsy Circuits and Immune Neuropathology Harvard Medical School/Beth Israel Deaconess Medical Center Boston, Massachusetts
Autism spectrum disorder (ASD) affects 1 in 40 individuals and is diagnosed by its deficits in sociability and increased repetitive behaviors and restrictive interests. Epilepsy, irritability/self-injurious aggressive behaviors, intellectual disabilities, and various other psychiatric and neurologic conditions often co-exist with autism. Our laboratory maps the neuronal circuitries and defines the circuitry defects that underlie these neuropsychiatric symptoms by modeling the genetic forms of autism and epilepsy in mice (Zhou et al. Nature Medicine 2009; Smith et al. Science Translational Medicine 2011; Czupryn, et al. Science 2011; Krishnan et al. Nature 2017). Concurrently, we are studying the postmortem brain tissues from individuals with ASD, both idiopathic and genetic forms, and identifying immune-related pathology that could account for a large proportion of ASD cases (Anderson, Autism Spectrum Disorders in Developmental Neuropathology 2018). We are developing single cell/nucleus sequencing technologies to define the critical neurons within each of the behavioral circuits mapped in the genetic mouse models of ASD. We are using the same methods to further define the pathogenic mechanisms in the postmortem brain tissues from humans with ASD. We are engineering additional new mouse models using Cas9/gRNA transgenics to investigate the mechanisms of the ASD immune-related pathology. We are also developing new Cre recombinase-activated AAV viral vectors for in vivo studies of neuronal circuits controlling social, aggressive, and communicative behaviors and epilepsy of relevance to mouse models of multiple different human genetic forms of ASD. We engineer these vectors so that they express selectively in the brain region where they are injected and in the cell-types within that region that selectively express Cre recombinase. In these vectors, we carry the following tools: 1) chemical- or light-based activation or inhibition of neurons (channelrhodopsin and DREADD); 2) fluorescent labeling of neuronal processes and synapses; 3) neuronal activity reporters; 4) gene repression or deletion mimicking ASD gene deletions (shRNA or Cas9/guideRNA); and 5) gene overexpression mimicking ASD duplications (cDNA). http://www.hms.harvard.edu/dms/neuroscience/fac/anderson.php
Interested candidates should inquire via email: firstname.lastname@example.org (2.12.19)
Postdoctoral Researcher Position in Cancer Epidemiology at the University of Wisconsin School of Medicine and Public Health
We invite applications for a postdoctoral researcher to join our active research group focused on genetic, molecular and social epidemiology of cancer risk. The research conducted in Warren Andersen Group consists of clinical and population-based studies, primarily utilizing data from large cohort studies with stored biologic samples, cancer consortia, and several epidemiological case-control studies. The ideal candidate will be interested in investigating the associations between genetic, social, and modifiable risk factors with breast and colorectal cancers. Individuals with superior communication and quantitative skills will be particularly competitive for the position.
The postdoctoral research and training program is designed to develop the skills necessary for success as an independent investigator. The training emphasizes grantsmanship, initiating and carrying out research projects, written and oral presentations, and facilitating local, national, and international collaborations. The postdoctoral researcher will have the opportunity to work on a wide range of established research projects, and lead their own research initiatives using a wealth of available data.
The postdoctoral researcher will be joining a research team where the overarching goal is to advance our understanding of the mechanisms driving the associations between social determinants, and genetic variants with cancer risk. Specific attention is given to the influence of sociocultural factors and genetic determinants on health disparities in colorectal cancer risk.
The position offers two to three years of postdoctoral support, competitive compensation commensurate with experience, an excellent benefits package, and travel to professional conferences. Research funds are available through internal pilot project funding mechanisms. Specific duties of the position include performing statistical analyses, writing manuscripts, and assisting in the development of grant proposals.
Eligibility: PhD in epidemiology, biostatistics, cancer biology, genetics, population health, or a closely related field. Preference will be given to applicants with experience with cancer epidemiology and/or genetic analysis.
To apply, please send CV, a cover letter that describes research experience and interests, and the names and contact information for three references to:
Dr. Shaneda Warren Andersen
Suite 1007B WARF Office Building
610 Walnut St
Madison WI, 53726
(Email Preferred) (posted 2.11.19)
Postdoctoral Fellowship at Harvard Medical School, Center for Computational and Integrative Biology (CCIB) at Massachusetts General Hospital
We are seeking a self-driven individual with expertise in computational genomics to lead projects investigating epigenetics and noncoding RNAs in immunology and development. Candidates must be self-driven, organized, work well in teams and have excellent oral and written communication skills. Candidates must be familiar with Linux-based bioinformatic software data analysis environments including Pearl/Python and R. Specific expertise in analysis of Chromatin Immunoprecipitation/DNA Sequencing (ChIP-Seq), Assay for Transposase-Accessible Chromatin (ATAC-seq) and/or RNA-seq will further strengthen the application.
The applicant will receive training in research, grant writing and career development and have the opportunity to collaborate with a vibrant research community within the Harvard Medical School, Massachusetts General Hospital and larger Boston area.
The successful applicant will conduct research within the
Dr. Jeffrey http://jeffreylab.mgh.harvard.edu/
and Mullen labs http://mullenlab.mgh.harvard.edu/
who investigate epigenomic regulation of immunity and long non-coding RNA regulation of stem cell development, respectively.
● Ph.D. in Bioinformatics, Computational Biology, Immunology, Genetics, Molecular biology, Biochemistry, or related field
● Experience in Linux-based environments
● Expertise with statistical analysis
● Excellent programming skills
● Demonstration of outstanding personal initiative
● Excellent teamwork, time management and organizational skills
● Ability to work independently in a fast-paced, dynamic environment
● Ability to present data to a multidisciplinary audience in a clear and concise manner
● Ability to meet deadlines and multitask efficiently is a must Principal
● Work with molecular and computational biology teams in the design and interpretation of omics experiments
● Understand the underlying code of established bioinformatics analysis algorithms so that they can be applied and modified to interpret high throughput profiling data
● Develop new analysis pipelines to better understand genomic data
● Monitor and evaluate new and emerging technologies and computational approaches
● Present scientific and technical data to both internal and external colleagues in a clear and concise manner
● Work independently to resolve time-sensitive issues and balance multiple projects
Interested candidates should send their cover letter, current curriculum vitae and the contact information for three references to KJeffrey@mgh.harvard.edu
Harvard University and Massachusetts General Hospital are equal opportunity/affirmative action employers. Women and minority applicants are particularly encouraged to apply. (1.30.19)
Biogen - Scientist II, In vivo-in vitro Genomic Editing. US-MA-Cambridge, Summary
The Translational Cellular Sciences Stem Cell & Genomic Engineering group seeks an accomplished Scientist II to lead in vivo and in vitro genomic editing efforts. The primary responsibility for this position will be to lead a team and contribute to generating genetically modified mouse/rat models and genetically modified iPSCs in support of Biogen’s neuroscience platform.
Requisition Number: 35379BR
Job Description: The preferred candidate will have strong molecular biology skills and an ability to rapidly integrate novel technologies. Additionally, the successful candidate will be highly motivated with a demonstrated ability to successfully take on challenges and quickly adapt to new responsibilities. He/she will accomplish our mission through open communication, innovation, teamwork, creative problem solving, and use of state-of-the-art technologies. As a Scientist II, the successful candidate is expected to contribute to strategic directions, prioritization and scientific ideas and will have significant impact on drug discovery/development projects and departmental goals.
Qualifications: The successful candidate will possess: •A deep knowledge of molecular biology and significant experience with genome editing technologies for the development of both in vivo and in vitro models. •Experience with multiple cell culture systems specifically including mouse ESC and human iPSC. •A knowledge of concepts of neurological diseases and mechanisms. •A keen understanding of experimental design, underlying scientific principles, and the ability to rigorously analyze and interpret results. •Strong interpersonal and organizational skills, ability to clearly communicate and to influence decision making through presentations. •An ability to work in a matrixed environment.
Education: This position requires a Ph.D. with 2-5 years of experience. Will also consider equivalent experience.
Job Listing: https://lnkd.in/e4Snm4G (1.23.19)
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