Non-Quad Job Opportunities

Job Opportunities
- Please note, these job postings are a courtesy to the HMS Postdoc community. Send any and all inquiries about job opportunities below to the listing organization, company or individual and not to the OPF. Employers: If you would like us to post your job opportunity, submit HERE.-

Research Fellow In Computational Genomics and Genetics | Division of Nephrology | Boston Children’s Hospital
A full-time Research Fellow position is available in a newly established laboratory of Dr. Dongwon Lee in the Division of Nephrology at Boston Children’s Hospital (BCH). BCH is a Harvard Medical School (HMS) affiliated hospital. The laboratory studies disease-associated genetic variants using computational approaches with a specific focus on transcriptional regulatory mechanisms. Dr. Lee has developed several machine-learning based methods for predicting regulatory elements and regulatory variants (Lee et al., Nature Genetics 2015). He also showed that these predicted regulatory variants explain a significant proportion of heritability in a tissue-specific manner (Lee et al., Genome Research 2018). The laboratory will continue to develop computational methods to model regulatory control of human diseases, by incorporating improved machine-learning algorithms and single-cell multi-omic data (genomic, transcriptomic, and epigenomic.) New computational frameworks will help discover the molecular mechanisms driving the development and progression of human diseases.
Requirements
1) The ideal applicant should have received a Ph.D. degree within 12 months or expect to do so within the following 12 months in computational biology, bioinformatics, biostatistics, computer science, or other related fields.
2) Strong programming skills in Python, C/C++, R or equivalent are required.
3) Experience with Unix/Linux and working with large genetic and genomic data in a cluster-computing environment is preferred.
4) Excellent written and verbal communication skills, and willingness to write grant proposals and manuscripts are necessary.
How to apply
Interested candidates should send a CV and one-page research narrative to:
Email: Dongwon.Lee@childrens.harvard.edu
Dongwon Lee, PhD
Division of Nephrology
Boston Children’s Hospital

(Posted 9.6.19)

Vor Biopharma
Vor Biopharma is a preclinical biotechnology company founded by leading scientists (including Siddhartha Mukherjee), and backed by top venture capital firms. Vor is developing targeted therapies based on engineered hematopoietic stem cells that are designed to transform outcomes for cancer patients. Vor uses gene engineering tools to develop novel cell therapies for the treatment of hematological malignancies. Vor is currently recruiting critical-thinking and technically sound molecular/cell biologists looking to make the jump to industry. Visit their website for more information HERE.

Associate Scientist/Sr Associate Scientist, Target Discovery | Vor Biopharma
The successful candidate will contribute
to the discovery of novel targets of Vor’s innovative pipeline.This will involve working within a team environment to execute experimental plans requiring skills in fundamental molecular biology, cellular engineering, hematopoietic stem cell, T cell and myeloid cell biology.

Key areas of responsibility
Routinely perform culture, editing and manipulation of primary cells and cell lines
Perform cellbiology, molecularbiology and biochemical assays including gene editing, viral transduction, DNA and RNA extraction, PCR/qPCR, flow cytometry and western blot
Participate in the design of experiments, the interpretation of data, and lead trouble shooting with oversight from senior scientific personnel
Participate in drafting standard operating procedures, work instructions, test methods, study protocols, and technical reports
Participate in drafting presentations and progress at regular internal research meetings
Maintain a clear, detailed laboratory notebook to document all experiments and findings
Comply with best safety practices

Qualifications
Bachelor’s or Master’s Degree in fields such as biochemistry/molecular biology, immunology, cancer biology, bioengineering, or related discipline is required (title and compensation commensurate with experience) or Master’s Degree with 2+ years of laboratory experience in an industry settingindustry preferred
Experience with mammalian cell culture
Experience with ex vivo genetic manipulation of hematopoietic stem cell or primary T cells, using gene editing tools (CRISPR, TALEN, or ZFN) and/or viral gene delivery
Excellent communication, organization, and technical writing skills
Strong problem-solving skills and the ability to work independently in startup environment
Immediate availability

Full job description HERE. Inquiries can be sent to: careers@vorbiopharma.com (Posted 9.5.19)

Associate Scientist, Molecular and Cell Biology | Vor Biopharma
The successful candidate will contribute to advancing Vor’s
engineered hematopoietic stem cell products. This will involve working within a team environment to execute experimental plans requiring skills in fundamental molecular biology, cellular engineering, and hematopoietic stem cell biology.

Key areas of responsibility
Routinely perform culture, editing and manipulation of primary cells and cell lines.
Conduct cell-based assays such as flow cytometry and colony-forming assay to evaluate phenotypic changes in gene modified cells.
Perform molecular biology work such as DNA and RNA extraction, PCR/qPCR, and next-generation sequencing library preparation, as well as protein-based assays such-as Western blot.
Implement sensitive genome-wide assays for various types of mutations and chromosomal rearrangements.
Processing of cells and tissues from xeno-transplanted animals.
Participate in the design of experiments, the interpretation of data, and lead trouble shooting with oversight from senior scientific personnel.
Participate in drafting standard operating procedures, work instructions, test methods, study protocols, and technical reports.
Participate in drafting presentations and progress at regular internal research meetings.
Maintain a clear, detailed laboratory notebook to document all experiments and findings.
Comply with best safety practices.

Qualifications

Bachelor’s or Master’s Degree in fields such as biochemistry/molecular biology, immunology, cancer biology, bioengineering, or related discipline is required (title and compensation commensurate with experience) or Bachelor’s Degree with 3+ years’ experience, or; Master’s Degree with 2+ years of laboratory experience in an academic or industry setting (industry preferred)
Experience with mammalian cell culture
Experience using gene editing tools (CRISPR, TALEN, or ZFN) as well as previous experience in gene editing
Previous experience identifying off-target sites is a plus
Experience in hematopoietic stem cell or CAR-T relevant experimental techniques, including both in vitro cellular assays and in vivo transplant models is highly desirable.

Full job description HERE. Inquiries can be sent to: careers@vorbiopharma.com (Posted 9.5.19)

Scientist/Sr. Scientist Molecular & Cell Biology | Vor Biopharma
The successful candidate will lead a project aimed at developing molecular biology tools to evaluate off target profiles for Vor’s engineered hematopoietic stem cell products. This will involve design and execution of an experimental plan comprised of fundamental molecular biology, cellular engineering and cellular and biochemical assay optimization to identify genome editing efficieny of CRISPR and other genome editing nucleases and their off-targets.

Key areas of responsibility
Develop and optimize assays to identify efficieny of genome editing nucleases in hematopoietic stem cells and other cell lines.
Prepare sequencing libraries for amplicon sequencing, GUIDE-seq, Digenome, Hybrid Capture, CIRCLE-seq or other off-target analysis approaches.
Profile gene expression signatures in bulk or single cell populations using qPCR, ddPCR and RNA-seq.
Generate editing reagents using Gibson, USER assembly or other relevant cloning strategies.
Primary/stem cell (human CD34+HSPCs, iPSC) and mammalian cell line cultureCoordinate with internal collaborators andexternal contract research as needed.
Design experiments, interpret data, and problem solve with a high level of independence and creativity to advance company's hematopoietic stem cell therapy platform.
Review, interpret and communicate data across functions within the research and/or project teams.
Understands project timelines and deliverables and plans/coordinates project work accordingly with departmental, functional and external stakeholders.
Draft standard operating procedures, work instructions, test methods, study protocols, and technicalreports
Create presentations and present progress to senior management.

Qualifications

  • Ph.D. in biological science or related discipline with 3-6 years of postdoctorate experience or 2-4 years of experience in biotech or pharma.
  • Strong scientific background and publication record with proven high levels of performance.
  • Previous experience identifying off-target sites using GUIDE-seq, Digenome-seq, CIRCLEseq or other is strongly preferred.
  • Lab skills and technical background of gene editing tools and principles (ZFN, TALENs, CRISPR, or DNA base editors). Optimizing CRISPR/Cas9-based gene editing is strongly preferred.
  • Library preparation for whole genome, amplicon sequencing or transcriptome library preparation – bulk or single cell RNA-seq – is strongly preferred
  • Experience in primary/stem cell and mammalian cell line culture (iPSC or HSPC experience a plus)

View full job description HERE. Inquiries can be sent to: careers@vorbiopharma.com (Posted (9.5.19)

Scientist/Sr. Scientist in Genome Engineering | Vor Biopharma
The successful candidate will lead a project aimed at developing
innovative ways to engineer Vor’snew generation of hematopoietic stem cell productsusing multiplex gene editing systems. This will involve design and execution of experimental planscomprised of fundamental molecularbiology techniques and biochemical/biophysical assays.

Key areas of responsibility

  • Evaluate existing gene editing systems (including ZFN, TALENs and CRISPR systems) and design/optimize new systems to enable multiplex genome editing capabilities.
  • Develop in vitro molecular biology and biochemical assays to analyze gene editing outcomes.
  • Design experiments, interpret data, and problem solve with a high level of independence and creativity to advance company's hematopoietic stem cell therapy platform.
  • Deliver results by creating presentations to effectively communicate progress to senior management.
  • Collaborate cross functionally between research groups.
  • Draft standard operating procedures, work instructions, test methods, study protocols, and technical reports.
  • Maintain a clear, detailed laboratory notebook to document all experiments/findings and comply with best safety practices.

Qualifications

  • PhD is required: Strong preference inmolecular biology, biochemistry, or related discipline.
  • 3-6 years of experience in postdoctoral training or in industry setting preferred.
  • Deep understanding of & hands on experience with gene editingandmolecular biology (including RNA/DNA extraction, gRNA design, molecular cloning, qPCR).
  • Experience with DNA repair, enzyme kinetics, biochemistry and mammalian cell culture.

Full job description HERE. Inquiries can be sent to: careers@vorbiopharma.com (Posted 9.5.19)

Scientist/Sr. Scientist, in vivoBiology | Vor Biopharma
The successful candidate will lead a project aimed at developing & optimizing Vor's engineered
hematopoietic stem cell products. This will involve design and execution of an experimental plan comprised of fundamental molecular biology, cellular engineering, hematopoietic stem cell biology, and humanized mouse model approaches.

Key areas of responsibility

  • Develop assays (in vitro & in vivo) to study hematopoietic stem cell behavior in response to cellular engineering.
  • Coordinate in vitro and in vivo testing at external contract research organizations and with other collaborators, as needed.
  • Design experiments, interpret data, and problem solve with a high level of independence and creativity to advance company's hematopoietic stem cell therapy platform.
  • Draft standard operating procedures, work instructions, test methods, study protocols, and technical reports.
  • Create presentations and present progress to senior management
  • Maintain a clear, detailed laboratory notebook to document all experiments and findings.
  • Comply with best safety practices.

Qualifications

  • PhD is required: in fields such as molecular biology, cellular biology, bioengineering, or related discipline.
  • 2+ years of experience postdoctoral training or in industry setting preferred.
  • Deep understanding of & hands on experience with studying hematopoietic stem cell biology required.
  • Demonstrated experience with NSG and related mouse models for studying hematopoietic stem cell function.
  • Experience with mammalian cell culture, including hematopoietic stem cells, and carrying out validation studies in vitro and in vivo, including FACS, ELISA, immuno-blotting, and immunohistochemistry.
  • Experience using gene editing tools (CRISPR, TALEN, or ZFN) is a plus.

Full job description HERE. Inquiries can be sent to: careers@vorbiopharma.com (Posted 9.5.19)

Assistant Professor of Cell Biology | Tenure Track | Harvard Medical School
The Department of Cell Biology invites applications for a tenure-track faculty position at the rank of Assistant Professor. We are seeking a highly motivated individual with demonstrated potential for creativity and excellence. Applicants in all areas of cell biology, ranging from mechanistic analysis of cellular processes to development, function, and dynamics of complex biological systems, are encouraged to apply. The ideal candidate will direct independent research and participate in graduate and medical school teaching. We welcome candidates with a PhD or MD/PhD and a record of outstanding research productivity.
The department offers a vibrant research community, with many opportunities for interactions within the broader Harvard and Longwood Medical Area community. This appointment provides a highly competitive start-up package and access to cutting-edge facilities, including advanced light and electron microscopy, computational image analysis, mass spectrometry, and high-throughput small molecule and genetic screening. 
APPLY HERE
Applicants should upload: (1) CV, (2) cover letter, (3) three-page statement of research (consisting of a one-page summary of past research accomplishments and a two-page summary of future research plans), and (4) 300-word max summary of your most significant manuscript or published article, along with the email addresses of three references. After you have finalized and approved the submission of your application materials, references will be notified automatically with instructions on how to upload their letters of support. References will have up to 2 weeks after the application deadline to submit their letters.
The deadline for completed applications is 11:59 pm Eastern Standard Time on Friday, October 18, 2019. All reference letters must be uploaded by 11:59 pm EST on Friday, November 1, 2019. (Posted 9.3.19)

Assistant Professor in Microbiology | Wheaton College
Wheaton College (Norton, MA) seeks to hire a tenure-track Assistant Professor of Biology with expertise in microbiology. The 3/2 teaching responsibilities include a course in general microbiology, introductory biology (Cells & Genes and/or Evolution & Ecology), and upperlevel courses in the candidate’s areas of expertise. The successful candidate will play an active role in guiding the future of the Biology and other Bioscience majors (Biochemistry, Bioinformatics, Environmental Science, and Neuroscience), maintain an active research program that engages undergraduates on multiple levels, and complement / add to existing strengths in the department. Successful candidates must provide clear evidence of, or potential for, excellence in teaching and mentoring of undergraduate researchers as well as a commitment to equity and inclusion in higher education. The successful candidate must have a Ph.D. at the time of appointment. 
Wheaton strives to be a community supportive of diverse perspectives and identities through inclusive and equitable institutional practices. Candidates should describe in their letter of application how they will support the College’s commitment to diversity, equity, and inclusion, whether through their teaching, scholarship, and/or service. Applicants should submit a cover letter, CV, statement of research interests, statement of teaching philosophy, list of potential courses, and contact information for three reference/letters of recommendation providers to be submitted online through the Wheaton College HR Department at http://jobs.wheatoncollege.edu/postings/2750. Applications will be accepted until September 23, 2019 or until the position is filled. (Posted 9.5.19)

Immediate Opening: Adjunct Instructor in Biology | Simmons University
Instructor needed for the following lab courses:
Genetics lab - Tuesdays, 3:00-5:50PM from Sept. 10th  to Dec 10th
Microbiology lab - Thursdays, 8:00AM-10:50AM from Sept. 12th - Dec. 12th
Microbiology lab - Thursdays, 12:00-2:50PM from  Sept. 12th - Dec. 12th
The salary is $3600.00 and the labs are all set up and ready to go. Contact Jane Lopilato, Ph.D., Chair, Associate Professor of Biology, Simmons University for more info and to apply. (Posted 9.3.19)

Faculty Member, Pathogen-Associated Malignancies | Fred Hutchinson Cancer Research Center | Integrated Research Centers | Seattle, WA
The Fred Hutchinson Cancer Research Center seeks to expand research on PAMs, including Hepatitis viruses and invites applications to fill a full-time laboratory-based faculty position. Encouraged to apply are virology, microbiology, or immunology faculty members wishing to establish an independent lab working on a virus or bacteria that is associated with cancer. Applicants from PhD, MD/PhD, or MD scientists will be considered at any rank. Please provide a curriculum vitae, a two to three-page research plan, three recent publications, and three letters of reference. The applicant review process begins as applications arrive and any application received by October 30th, 2019 will be guaranteed consideration for the position. More information HERE and to apply HERE. (Posted 8.23.19)

Program Manager | Continued Umbrella of Research Experiences (CURE) | DF/HCC
The CURE Program Manager has a primary responsibility for developing, managing and coordinating the activities related to the research training efforts focused on enhancing the pipeline of under-represented students in biomedical research across the seven institutions which encompass Dana-Farber/Harvard Cancer Center. The program manager is responsible for the program elements across three research training programs including the inaugural program, Continued Umbrella of Research Experiences, (CURE), Young Empowered Scientists for ContinUed Research Engagement (YES for CURE), and the Summer Program to Advance Research Careers (SPARC). The position has direct supervision of over 90 trainees during the summer and 40+ trainees during the academic year.
Full job description and to apply -
HERE (Job Code - 2019-16474). (Posted 8.7.19)

Postdoctoral Fellowship in Clinical/Cognitive Neuroscience Research | Martinos Center for Biomedical Imaging and the Psychiatric Neuroimaging Division of the Psychiatry Department | MGH-Charlestown and HMS
The position will involve investigating the role of sleep in memory consolidation, how these processes go awry in schizophrenia and autism, and the effects of pharmacological and other interventions.  Our work has linked cognitive deficits to specific heritable mechanisms (sleep spindles and other sleep oscillations) and we are seeking effective interventions.  In collaboration with Dr. Robert Stickgold’s lab at Beth Israel Deaconess Medical Center, we are extending and expanding this basic and clinical research program using state-of-the art tools including high density EEG, MEG, DTI, functional connectivity MRI, fMRI, and behavioral studies.  We are seeking someone to participate in these foundation and NIMH-funded investigations who is familiar with cognitive neuroscience, neuroimaging methodology including MEG and/or EEG and data analysis, and is interested in developing research questions and optimizing analysis streams tailored to the study aims and populations.  New approaches and ideas are encouraged, as are independent projects that dovetail with current studies.  The position requires working closely with the PI, as well as with Dr. Stickgold, other Martinos Center investigators, particularly Dr. Matti Hamalainen, Director of the MEG Core Lab, and labmates to design studies, acquire data, and develop, explore, improve and apply data analytic techniques. Training in clinical research and in the acquisition, analysis, and interpretation of neuroimaging data will be provided.
Requirements: PhD (or MD) in neuroscience, psychology, engineering or a related discipline and a strong research background are required. Ideal candidates would have extensive experience in data analysis, a background in computational neuroscience and/or signal processing, be proficient in Matlab/Python and be interested in methods development. The following are also beneficial: experience with MEG/EEG data analysis/methodology, background in cognitive neuroscience, experimental psychology and sleep; interest/experience with clinical populations; and experience in task design and analysis for cognitive experiments.
Position available immediately.  Interested applicants should email: (a) CV, (b) statement of postdoctoral and career goals, (c) writing sample (e.g., a published manuscript), and (d) letters and/or contact information for three references to Dara Manoach at Dara.Manoach@mgh.harvard.edu.  More information HERE. Stipend levels are in line with experience and NIH.  A two-year commitment is required. (Re-Posted 8.8.19)

Biochemistry Postdoctoral Research Fellow | Dubach Lab | Center for Systems Biology MGH
Description: The
Dubach Lab has an opening for a highly qualified postdoctoral fellow with a strong background in chemistry and biochemistry. Our group is housed within the Center for Systems Biology and the newly formed Institute for Innovation in Imaging with goals of developing new imaging and analysis approaches that make the unmeasurable in biology measurable. Our research leverages novel fluorescence sensor design and optical microscopy to develop new quantitative imaging tools that enable measurements not otherwise possible. Our group strives to perform highly innovative research that will also improve patient outcomes in the clinic. We value publications, but also individual learning, growth and an exciting work environment. Our NIH-funded projects seek to develop more methods to study cellular activity to better understand fundamentals of molecular and cellular biology, find more effective therapies and build better sensors. We are seeking a fellow to join our efforts in developing fluorescence sensors using the combination of noncanonical amino acids, turn-on bio-orthogonal click chemistry and polarization microscopy to measure intracellular protein activity across a range of medically important proteins.
Responsibilities: We seek a postdoctoral research fellow with a background in synthetic chemistry, biochemistry and molecular biology. This fellow will work with the PI, lab members and collaborators to develop fluorescent sensing tools that utilize innovate chemistry, imaging and analysis approaches. The successful applicant should have a strong work ethic, openness to thinking outside the box and interest in collaborative research. Prior experience with techniques such as fluorophore synthesis, protein engineering, cell culture, fluorescence microscopy and molecular biology are preferred. Our focus on translational, cutting-edge research provides opportunities to pursue careers in academia or industry. We encourage fellows to seek funding through grants and/or collaborate with industry partners.
Requirements: The minimum requirement is a PhD or MD. Candidates should demonstrate a proven track record of achievement, ability to publish, interest in performing impactful research and proficiency in written/spoken English. To submit application contact
Serena Sullivan. (Posted 8.1.19)

Imaging and Analysis Postdoctoral Research Fellow | Dubach Lab | Center for Systems Biology MGH
Description: The
Dubach Lab has an opening for a highly qualified postdoctoral fellow with a strong background in microscopy and image analysis. Our group is housed within the Center for Systems Biology and the newly formed Institute for Innovation in Imaging with goals of developing new quantitative imaging and analysis approaches that make the unmeasurable in biology measurable. Our research leverages optical microscopy, intravital imaging, and cellular biology to make illuminating measurements of cellular and cancer biology using imaging techniques such as polarized fluorescence microscopy. Uniquely, we study single cell and dynamic phenomena that provide more discrete information that can be captured with standard approaches. We have a strong background in evaluating cancer pharmacology at the single cell level using new imaging tools and analysis. Our group strives to perform highly innovative research that will also improve patient outcomes in the clinic. We value publications, but also individual learning, growth and an exciting work environment. Our NIH-funded projects seek to develop more methods to study cellular response to cancer therapy and increase the impact promising drugs have on patient outcomes. The goals of the current project are more focused on computational evaluation of single cell response using tools such as Matlab, Python or TensorFlow.
Responsibilities: We seek a research fellow with a background in optical imaging, computational analysis, cellular biology and molecular biology. This fellow will work with the PI, lab members and collaborators to develop new analysis tools to better study cellular and molecular signaling and optimize therapeutic intervention. The successful applicant should have a strong work ethic, openness to thinking outside the box and interest in collaborative research. Prior experience with techniques such as cell culture, molecular biology, and programming are preferred. Our focus on translational, cutting-edge research provides opportunities to pursue careers in academia or industry. We encourage fellows to seek funding through grants and/or collaborate with industry partners.
Requirements: The minimum requirement is a PhD or MD. Candidates should demonstrate a proven track record of achievement, ability to publish, interest in performing impactful research and proficiency in written/spoken English. To submit application contact
Serena Sullivan. (Posted 8.1.19)

Introductory Biology Lecturer | MCPHS University
Located on Longwood Ave, MCPHS University is seeking an adjunct lecture instructor to teach Biology I during the Fall 2019 semester. BIO.151 is the first half of a one-year course sequence covering cell structure and function, metabolism, heredity, healthcare applications of molecular biotechnology, human organ systems, and evolution. This course, taken by approximately 250 students, is scheduled for Tuesdays and Thursdays from 4:30-5:45 p.m. Two additional office hours each week are required. Qualifications: MS, ABD or PhD in Biology, Biochemistry, Cell Biology, Genetics, Molecular Biology or a related field, and a minimum of one year of experience teaching undergraduate biology courses. Apply HERE. (Posted 7.29.19)

Adjunct Faculty Fall 2019 | CHEM110 Lab | Fridays, 8-10:50am | Simmons University
Simmons University is seeking an adjunct faculty instructor for a lab from 8-10:50am on Fridays for the introductory general/organic/biochemistry for nurses (CHEM 110). If you are interested in being considered for this position, please contact Dr. Cherie Ramirez with your current CV as soon as possible. (Posted 7.29.19)

HMX Interns | Cancer Genomics and Precision Oncology Course | Apply by July 31, 2019
HMX is looking for postdoctoral researchers and clinical fellows in the HMS community who have research or clinical experience in the field of cancer and are interested in gaining experience in online education. This is a paid opportunity.
HMX offers fully online courses intended for students who have an interest in health care careers as well as professionals working in life sciences and health care related careers. These courses are designed to address the foundational concepts in important biomedical subjects. We are also developing a new series of courses designed to cover more advanced, cutting-edge topic areas.  More information about our courses can be found at https://onlinelearning.hms.harvard.edu/hmx.
We are currently recruiting HMX interns to staff our Cancer Genomics and Precision Oncology course.  Initially, this will involve moderating the HMX "Ask a Question" forums in this course. Responsibilities include monitoring the discussion forums on a regular basis, responding to student questions about the course content, and escalating questions appropriately to the HMX staff. There may also be opportunities to provide feedback on and develop course content, or to participate in other collaborations with HMX.  The workload will be variable but generally will be around 5 hours of work per week, which can be done remotely at flexible hours. Successful candidates will be part of a small team of moderators, which provides additional flexibility for busy schedules.
Any current postdoctoral researchers or clinical fellows with a PhD or MD are welcome to apply. If interested, please email Christine DeGennaro by July 31 with your current CV, and a cover letter describing your interest in and qualifications for the position and your availability over the next 12 months. (Posted 7.19.19)

Postdoctoral Fellow Position | Department of Neurosciences | Cleveland Clinic
The research goal is to understand the anatomical and functional organization of the meninges and their impact on physiological and pathological brain function, with a hope to develop new strategies to prevent, treat and cure neurological disorders.
The candidate will focus on understanding the role of the meningeal lymphatic vasculature in brain maturation in normal and disease rodent models.
The Louveau Lab is seeking highly motivated, independent, curious and creative individuals with a Ph.D. and/or M.D. degree with laboratory expertise in neuroscience and/or immunology and/or bioinformatics or related fields. Experience in animal experiment is strongly recommended. Candidates are expected to lead a project and establish a collaborative research and must have excellent verbal and written communication skills. Applicants should send a cover letter, CV and complete contact information for three references to Dr. Antoine Louveau. (Posted 7.21.19)

Postdoctoral Population Science Fellowship in Cancer and Cancer Health Disparities | University of Massachusetts Boston and Dana-Farber/Harvard Cancer Center 
Fellowship Description: University of Massachusetts Boston (UMass Boston) and Dana Farber/Harvard Cancer (DF/HCC) jointly announce a Post-Doctoral Fellowship Program in Population Science designed to ensure a diverse and highly trained workforce to meet the national need for highly skilled faculty and researchers committed to better understand and address cancer health disparities. This program is designed to provide an additional year of support to a Post-Doctoral Fellow who is currently engaged in a research post-doctoral program and seeks to extend their fellowship for an additional year of support. 
Eligibility Criteria:
-
Actively engaged in a Post-Doctoral Fellowship program with a primary research interest in understanding and addressing cancer health disparities
- Demonstrated successful progress and outcomes during first three years of post-doctoral experience. 
Applicants from various socioeconomically disadvantaged, racially or ethnically diverse backgrounds are strongly encouraged to apply. 

Apply Now for September 2019 admission. Interested candidates should submit following to: Karen Burns White 
A letter of interest must include:*
- Name of fellowship program 
- A summary of the research plan, including progress/achievements to date 
- List of manuscripts, publications, conferences and presentations completed and those in preparation 
- Explanation of a  research plan and goals to be accomplished during the additional year
- Description of career transition plan pursuant to advancing to an independent research and/or faculty position
- Letter of reference from current faculty sponsor/principal investigator 
- An up-to-date curriculum vitae 
*Upon consideration we will request a copy of your fellowship application from the program director. (Posted 7.2.19)

Postdoctoral Researcher, Translational Medicine | Boston Pharmaceuticals
Position Summary: The Postdoctoral Researcher will have a critical role in defining and executing on translational strategies across the product portfolio. This individual will focus on developing and integrating non-clinical biomarker data (publicly available, historical or newly generated by CRO or academic partners) into the clinical development plan for the program.
Roles & Responsibilities:
- Participate in study and program specific meetings
- Provide proposals focused on demonstrating target engagement, pharmacodynamic response to Boston Pharmaceuticals compounds
- Contact and serve as liaison with external partners (academic or CROs) to generate key biomarker data
- Support publication strategy with the goal of presenting at one external meeting and drafting one manuscript focused on translational research / biomarkers
- Organize and maintain study data and program files
Qualifications:
- PhD in biological science
- Advanced knowledge and experience with translational in vitro and in vivo models
- Research expertise with primary human specimens a plus
- Deep understanding of the immune system preferred
- Proficiency in Microsoft Office software (e.g. Outlook, Word, Excel, and PowerPoint)
- Ability to perform in fast-paced, dynamic, constantly evolving environment
- Excellent communication and organizational skills and attention to detail
- Strong time management skills; ability to prioritize multiple tasks efficiently
- Resourceful and able to handle multiple and changing priorities
- Ability to think creatively and independently and be proactive
- Ability to understand team’s objectives and goals and assist in reaching them
- Ability to exercise discretion when managing confidential information
- Strong team player: demonstrated ability and willingness to work on a team, assist team members as needed and accomplish tasks required to achieve goals
Salary & Benefits: Postdocs come to Boston Pharmaceuticals after completing their doctorate or with some years of postdoctoral experience. Postdoctoral tenure at Boston Pharmaceuticals are on a yearly basis for up to two years. Salary will commensurate with experience. Postdocs are eligible for healthcare benefits and vacation. Apply HERE (Posted 6.25.19)

Research Scientist, Molecular Virologist | Department of Microbiology | HMS
The Yang Group is currently recruiting a molecular virologist to work with a team of medicinal chemists, biochemists, and structural biologists in developing novel small molecule antivirals.  Preference will be given to individuals with prior experience with flaviviruses, but applicants with experience in any area of positive-strand RNA virology are encouraged to apply.  Most important is that you thrive working in a collaborative and fast-paced environment and that you are willing to learn and evolve as a scientist.  This is a great research scientist level position if you aren’t sure or if you are sitting on the academia versus industry fence, because you can learn skills relevant to industry while still training in an academic environment (i.e. answering questions is more important than making products).
Qualifications: A Ph.D. in molecular virology, including prior work with flaviviruses and/or hepatitis B virus is preferable.  Must be proficient in molecular biology techniques required for performing reverse genetics experiments to generate and characterize recombinant viruses.  Experience in analyzing viral gene expression and viral genome replication. Ability to independently design experiments to address mechanistic questions.  Excellent quantitative and communication skills and an ability to collaborate are essential.
Interested candidates should email Priscilla_Yang@hms.harvard.edu and include a cover letter, CV, statement of professional interests, and contact information for three letters of reference. Applicants may also send the material to Dr. Priscilla Yang, Department. of Microbiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA  02115. (Posted 6.14.19)

Senior Scientist, Computational Biology | Celsius
Brief Job Description: We are seeking innovative and collaborative computational biologists, data scientists and AI researchers at all levels to work on groundbreaking single cell genomics projects changing the landscape of therapies for cancer and autoimmune diseases. Team members will play key roles in integrating and mining multiple internal and external datasets at massive scale generated by single cell RNA-seq data from human patients. A critical component of the job will be to develop and implement innovative analysis strategies to generate focused hypotheses for the identification of new therapeutic targets. Full description and to apply (Posted 6.14.19)

Field Application Scientist (95837BR) | Thermo Fisher Scientific | New England
Brief Job Description: When you are part of the team at Thermo Fisher Scientific, you’ll do important work, and you’ll be valued and recognized for your performance. With talented managers and inspiring coworkers to support you, you’ll find the resources and opportunities to make significant contributions to the world.
How will you make an impact?
Provides scientific expertise, applications support and training to customers on Thermo Fisher Scientific’s Applied Biosystems brand real-time PCR instruments through a variety of interfaces including in-person, phone and email communications. Partners with sales reps in the field to deliver product line specific pre- and post-sales related customer support activities and solve customer escalations effectively. Acts as a trusted expert to our customers, thereby increasing customer satisfaction and loyalty and contributing to the overall success of the business.
This role is a remote, home office-based position requiring travel that may range from 60-75%. Primary territory responsibility will be Massachusetts, New Hampshire, Maine and Rhode Island with the preferred candidate based in or around Boston, MA. Full description and to apply (Posted 6.14.19)

Postdoctoral Fellow in Biomedical Science (Position# 00011973) | Tufts School of Dental Medicine
Description: We are seeking a postdoctoral fellow in the field of biomedical science for the Facial Animation Laboratory at Tufts University School of Dental Medicine. Applicants are sought to help with qualitative research methods in one or two of the following research areas: grounded theory, content analysis, discourse analysis, framework analysis, etc. The postdoctoral fellow will be working under the supervision of Dr. Carroll Ann Trotman and supported by her current NIDCR grants. 
Qualifications: The postdoc should have a PhD degree in the biomedical science field. S/he should be relatively independent and able to generate and propose feasible hypotheses. Experience with 3D imaging and methods are preferred. S/he has excellent composition and writing skills for manuscripts.  The postdoc fellow should be able to communicate and collaborate effectively with other lab staff including project administrator, coordinators, and students. 
Application Instructions: Interested applicants should submit a current curriculum vitae. Please submit application documents electronically HERE. Review of applicants will continue until a candidate has been selected. (Posted 6.6.19)

Postdoctoral Fellowship in Gene Editing and Tissue Engineering (Position#00011972) | Tufts School of Dental Medicine
Description: The Tufts University School of Dental Medicine’s Department of Diagnostic Sciences invite applications for a Postdoctoral Fellowship in Gene editing and Tissue engineering.  This post-doctoral fellowship is an opportunity to work on a project in the laboratory of Dr. Jonathan Garlick lab in collaboration with a cutting-edge startup company.  Their goal is to use gene editing and tissue engineering to create immuno-privileged tissues.  This postdoc will be responsible for leading development and working with technicians in the lab to create and culture CRISPR/Cas9 edited porcine and human cells for the creation of 3D human equivalent tissues. This is a one-year appointment, and may be extended to 2-years, contingent on the meeting of milestones and sponsor funding.

Responsibilities:

  • Lead development of CRISPR/Cas9 edited porcine and human cells
  • Work with lab and startup company to develop experimental roadmap
  • Culture human and porcine cells, and engineer 3D tissues
  • Perform and analyze sequencing to verify CRISPR edits
  • Work with technicians to run histological analysis of tissues
  • Research and advise on innovations in fields related to model development
  • Present data to lab and company
  • Participate in general lab upkeep

Qualifications:

  • Completion of a PhD in molecular biology or similar field
  • Strong background in CRISPR/Cas9-mediated genome editing, including gene design and construction, editing efficiency characterization, clonal selection, verification of edits
  • Background in mammalian cell culture
  • Experience in running and analyzing DNA sequencing analyses
  • Experience in phenotypic analyses (IHC, Western Blot, ELISA, qRTPCR)
  • Ability to work independently, and to plan and execute complex long term research projects
  • Strong record of productivity, motivation, and adaptability
  • Ability to work collaboratively with excellent oral and written communication skills

Application Instructions: Interested candidates should submit a curriculum vitae, cover letter, a list of three recommenders (name and contact information), and a brief statement describing their background and research training HERE. Questions can be directed to Dr. Jonathan GarlickTrainees must be citizens or a non-citizen national of the United States or have been lawfully admitted for permanent residence at the time of appointment. (Posted 6.6.19)

Lab Automation and Imaging Specialist | The ICCB-Longwood Screening Facility at Harvard Medical School
The ICCB-Longwood Screening Facility at Harvard Medical School supports early stage drug discovery and translational research projects. It was one of the first screening facilities established in academe and attracts small molecule and functional genomic (arrayed siRNA and sgRNA/CRISPR) high throughput screening projects from research institutions nationwide.We are seeking a Lab Automation and Imaging Specialist who will work with other ICCB-L team members to help investigators develop and optimize high throughput assay protocols and help to run screening campaigns. Responsibilities will include operation of laboratory automation equipment, helping investigators optimize image acquisition and analysis protocols, and training researchers on use of select screening instruments. In addition, this position will contribute to the maintenance of instruments, associated databases and small molecule and functional genomics screening libraries. This position will have the opportunity to attend group meetings and seminars at Harvard Medical School and give presentations to colleagues.
Requirements: College degree (B.A., B.S., M.S, Ph.D.) and minimum of 5 years of related experience, with a background in molecular biology, cell biology, or biochemistry, with demonstrated experience in image-based research and analysis. Candidate is expected to have excellent communication skills (verbal and written), attention to detail, and enthusiasm for basic and translational research. Candidate must be extremely organized, capable of multitasking and have strong computer skills. The candidate should be able to work independently and as part of a team. Experience with databases, Excel, and image analysis software required. Experience with laboratory automation desired. 
Please email application letter, CV and three references to iccbl_search@hms.harvard.edu (Posted 6.3.19)

Postdoctoral Fellowship - MassGeneral Hospital - Autism Intervention Research Network on Physical Health (AIR-P)
Summary
This position will be based in the Department of General Academic Pediatrics at the MassGeneral Hospital for Children and supervised by Dr. Karen Kuhlthau, PhD (Associate Professor of Pediatrics and PI of AIR-P).  The Autism Intervention Research Network on Physical Health (AIR-P) is a 12-site clinical research network with a two-fold mission: (1) to promote a sustainable national system of community accessible programs offering state-of-the-art comprehensive and coordinated medical care for all children and adolescents with autism spectrum disorders (ASD) and (2) to develop evidence and support the improvement of medical care for these children and their families. The AIR-P fellow will conduct original research and/or analyze data from existing AIR-P datasets.   While this position will be housed at MGHfC where the network Clinical Coordinating Center is located, the candidate will work collaboratively with experts from our 12 AIR-P sites to synthesize these various data sources to further advance AIR-P’s mission.  
Responsibilities
We anticipate that the fellow would work on a intervention project that provides a mind body intervention to siblings of children with ASD to provide them with skills to improve resiliency.   The Postdoctoral Fellow will also contribute to network activities that best align with their area of expertise (e.g. ECHO Autism collaborative, the Autism Learning Health Network (ALHN), Physical Exercise to Reduce Anxiety in Underserved Children with ASD).
Basic Requirements
Candidates must have a doctoral degree in Health Services Research, Epidemiology, Public Health, Psychology, or a related field. Curriculum in and/or experience with biostatistics, data mining and clinical research will be necessary for this opportunity. Preference will be given to those with a background in developmental disabilities, special healthcare needs, or pediatric research. The candidate interested in this position must be highly motivated, willing to learn and demonstrate initiative in assigned tasks. Excellent written and verbal communication skills are crucial.
Additional Requirements
Experience with SPSS, STATA, SAS, or R is desirable.
Terms
This is a one-year term appointment, which aligns with the final year of a 5-year grant. The option for a second-year is conditional on the network receiving renewed funding from the Health Resources and Service Administration (HRSA) and satisfactory performance.
How to apply
Email applications including curriculum vitae, summary statement of personal objective and research interests, PDFs of the best two papers, as well as, the names and email addresses of three references to
JGFarmer@mgh.harvard.edu  (Posted 5.9.19)

Beth Israel Deaconess Medical Center - Postdoctoral Research Fellow Position(s) Available
We are seeking a highly motivated postdoctoral fellow to join the Schulman laboratory in the Division of Hemostasis and Thrombosis at Beth Israel Deaconess Medical Center (Boston, MA).
Our laboratory is focused on the initiation of blood coagulation, with particular attention to the tissue factor (TF) pathway. Inappropriate TF procoagulant activity underlies substantial human suffering, including that due to myocardial infarction, venous thromboembolism, cancer-associated thrombosis, and stroke. TF expression and activity must therefore be carefully regulated in vascular tissues to enable hemostasis following injury but prevent pathologic thrombosis. We combine functional genomics, human and rodent genetics, cell biology, and protein biochemistry to dissect the TF-dependent initiation of blood coagulation.
As the contribution of cellular TF is not captured by routine coagulation testing, these novel modifiers of human bleeding and thrombotic risk remain undetected in human populations. Our team is well integrated into the collegial Division of Hemostasis and Thrombosis at Beth Israel Deaconess Medical Center. In addition, our laboratory is situated in the heart of the Longwood medical area and adjacent to Harvard Medical School, enabling immediate access to vast educational opportunities, technical resources, and clinical/scientific expertise.
Applicants should have an M.D., Ph.D., or M.D./Ph.D. degree, substantial research experience, and a commensurate publication record. Proficiency in modern molecular biology techniques is essential. Expertise in bioinformatics, programming in Python, and/or prior experience analyzing functional genetic experiments is not required but highly valued.
Interested applicants should email a CV and three references to Sol Schulman (sschulm1@bidmc.harvard.edu) (Posted 5.8.19)

Postdoctoral Fellow Cardiometabolic Disease and Drug Discovery, BIDMC, Harvard Medical School
Topics: Human genetics, metabolic diseases, chemical biology, zebrafish models
Description: We are seeking a creative and enthusiastic Postdoctoral Fellow to lead a NIH-funded project that leverages multiomic human data to identify novel cardiometabolic disease-associated genes. The goals of this project are to determine the function of these genes and to develop small molecules to modulate their activity through innovative model generation and functional screens.
Requirements: PhD or graduating with a PhD in the summer of 2019 and a strong background in CRISPR/cas genome editing and/or zebrafish models.
Highlights: The position provides outstanding opportunities for professional growth and career advancement through a formal mentoring program. Additionally, as this position has joint appointments with Harvard Medical School, BIDMC, and the Broad Institute, and there will be many opportunities to benefit from diverse and vibrant scientific environments. We pay above the NIH salary line.
Lab: We are located at the Center for Life Sciences in the Harvard Longwood Medical Campus. https://scholar.harvard.edu/anjali-nath-lab
To Apply: Interested candidates should send their cover letter highlighting past research experiences and current research interests, curriculum vitae, and contact information for three references to Dr. Nath (anj.nath.lab@gmail.com).  (Posted 5.8.19)

Staff Scientist Position Opening – Boston Children’s Hospital, The Cantor Laboratory
The Cantor Laboratory is accepting applications for a Staff Scientist position.  The major focus of the laboratory is to further understand the gene regulatory mechanisms that control normal hematopoiesis and how their dysregulation contributes to human leukemogenesis.   Other current active areas include translational projects aimed at reducing the risk of leukemia development in patients with leukemia predisposition syndromes, as well as efforts to enhance in vitro platelet production from stem cell sources for transfusion purposes.  We use a variety of techniques including ChIP-seq, RNA-seq, ATAC-seq, 3D chromatin interaction analysis, CRISPR/Cas9 screens, mouse models, human CD34+ cell systems, and human genetics.
The candidate should have a PhD and completed post-doctoral training, preferably within the hematology field.  He/she should have strong molecular biology skills.  Prior experience with mouse techniques, flow cytometry, and hematopoiesis assays is preferred.  The candidate should have a track record of productivity in peer-reviewed journals, good communication skills, and the ability to work cooperatively with other members of the laboratory. 
Job responsibilities will include leading/contributing to specific research projects within the laboratory, collaborating with the PI in preparation of scientific papers and grant applications, advising other lab personnel on technical and scientific approaches, assisting with outside lab collaborations, and maintaining/establishing lab techniques.
Interested applicants should send their CV, a cover letter summarizing their background and research interests, and contact information for three references to:
Alan Cantor, MD, PhD
Associate Professor of Pediatrics
Boston Children’s Hospital and Dana-Farber Cancer Institute
Harvard Medical School
alan.cantor@childrens.harvard.edu
617-919-2026
*This is not considered a faculty level position at Boston Children’s Hospital or Harvard Medical School.  (Posted 5.1.19)

MGH/MIT CURT seeks a full-time Post-doc research fellow to join our collegial and diverse multidisciplinary team. This position offers experience in both basic and clinical research in medical ultrasound and provides the candidate with a unique opportunity to be part of a highly energetic group working to translate research into clinical care. 
The successful candidate will be expected to show initiative and creativity, to proactively develop his/her research interests and to work effectively with others toward shared goals. Candidates who seek a long-term academic career will have tremendous growth opportunities, access to committed mentors, and assistance in applying for career development and research grants. There will be many opportunities for mentorship from MIT and Harvard scientists working in close collaboration with MGH physicians and scientists.
Applicants should send a cover letter describing research experience, interests and goals, a CV with a full list of publications as well as three references (including one from a current supervisor) to Masoud Baikpour, MD at mbaikpour@mgh.harvard.edu. Please indicate if there are any issues about the timing of contacting your supervisor. Interviews will be conducted by a multi-disciplinary team of clinicians and scientists. The position is full-time with benefits. The salary is commensurate with experience.
The Massachusetts General Hospital is an Equal Opportunity/Affirmative Action Employer.
Complete details attached(Posted 4.26.19)

Brigham and Women’s Hospital: Project Manager, Department of Neurology
The Project Manager functions independently and under the direction of the Chair and the Vice Chair of Academic Affairs for the Department of Neurology. A hybrid position utilizing strong scientific skills while offering opportunities to work closely administratively with all Divisions within the Department of Neurology as well as with the Central Offices of Neurology Research Administration and Finance. This is a senior level position with prior academic or industry experience in clinical research project management preferred.

The position is divided into two main areas of concentration:
1. Management of daily operations of the Chair’s Research Portfolio including all aspects of project direction and administration. In addition, the position involves being a part of collaborative projects in translational neuroscience, helping to organize and direct new programs within our large Translational Research Department.  

2. Management, in collaboration with the Chair and Vice Chair of Academic Affairs, of the department’s faculty development and the Harvard Medical School (HMS) promotion process.  This includes coordination of promotion candidate review by the departmental promotions committee, pre-submission assembly of candidate promotion material, and liaison with the HMS Neurology Executive Committee and HMS Dean’s office regarding candidates proposed by the department.  The Project Manager will also work with the Vice Chair of Academic Affairs to develop a faculty mentoring program aligned with HMS promotion requirements.  The Project Manager will also enhance communication and education of the departmental faculty around HMS promotions.
Details and complete job listing here.

Nestlé - R&D Specialist in Gut-Brain Axis (Lausanne)
To complete our Brain Health Department, we are looking for a R&D Specialist Gut-Brain Axis who is able to demonstrate excellent creative skills, to drive product innovation at Nestlé Research. Demonstrating excellent creativity and scientific curiosity, you will develop and lead highly collaborative research projects to identify nutritional interventions, leveraging the gut-brain axis to support brain health across lifespan. You will lead the design, implementation and interpretation of in vitro and in vivo preclinical studies as well as contribute to scientific communication material, patents and peer-reviewed publications. 
Key responsibilities 
- Develop and lead highly collaborative research projects to identify nutritional interventions leveraging the gut-brain axis to support brain health and healthy aging
- Integrate scientific knowledge with business, intellectual property and regulatory constraints to identify research directions relevant to product innovation
Lead the design, implementation and interpretation of in vitro and in vivo preclinical studies
- Work with clinical neuroscientists to design human intervention studies
- Contribute to scientific communication material, patents, and peer-reviewed publications
Required Profile
- Neurobiologist with PhD and 3+ years postdoctoral research experience
- Deep expertise in microbiota-gut-brain axis biology, demonstrated with high impact publications in the field
- Extensive experience with the design of in vivo experiments to study the molecular, cellular, and physiological aspects of gut-brain signaling in mammals, and to study the impact of the gut-brain axis on behavior and brain health
- Expertise in nutrition and nutritional interventions is a plus
- Fluent in written and spoken English, any other language is an asset
Please apply in English at https://jobs.nestle.com/en/home
LinkedIn Job posting: https://www.linkedin.com/jobs/view/1205175312/  (Posted 4.9.19)

Postdoctoral Fellow – Immunology and Microbiome Research - Division of Immunobiology, Joslin Diabetes Center and Department of Microbiology & Immunobiology, Harvard Medical School, Boston, MA
Description: The Kostic laboratory, based at the Joslin Diabetes Center and the Harvard Medical School Department of Microbiology and Immunobiology, works at the cutting-edge of the microbiome and immunology fields. Our work is driven by the goal of one day using the human microbiome to prevent, treat, and even reverse type 1 diabetes.
We are currently seeking a highly talented immunologist to join the team and work on developing this program.  Though we are interested in candidates from diverse scientific backgrounds, experience and a deep understanding of mucosal immunology is required. We will consider candidates with a PhD, MD, or MD/PhD possessing a proven record of scientific advances leading to high quality publications.
We are working to understand and extract the clinical relevance of the human gut microbiome as it applies to health and disease. Using patient derived clinical samples and mouse models of diabetes, we use genome/metagenome mining combined with bacterial culture-based screening to identify human microbiome-derived natural products with immunomodulatory capability that mediate host-microbe interactions. Our internal gnotobiotic mouse facility will be leveraged to interrogate how these novel bioactive molecules impact the immune system and disease. Our goal is to combine the unique technical and scientific expertise in our laboratory to engineer human symbiotic microbes that we believe will drive innovative drug discovery in this important emerging area of science.
Full listing and how to apply via LinkedIn: https://lnkd.in/eKZkuzZ  (Posted 4.4.19) 

Post-doctoral fellow - Parikh Laboratory, Beth Israel Deaconess Medical Center, Harvard Medical School
Topics: molecular biology, metabolism, physiology, Location: Boston, Massachusetts, USA
We are seeking a Postdoctoral Fellow who will lead NIH-funded projects to understand the molecular processes regulating homeostasis of NAD+. NAD+ regulation in metabolically active organs may be pivotal both for cell-autonomous functions during acute stress and for generalized physiological disturbances such as impaired organ function. The successful applicant will apply systematic functional screens (e.g., CRISPR) to identify central control mechanisms for NAD+ balance and will lead experiments to evaluate metabolism and physiology across cellular and in vivo models of acute stress.
Candidates must be enthusiastic, passionate and self-motivated with a commitment to career development. You will have the support of an organized Departmental Postdoctoral training program including opportunities to present your work and bi-annual review of a personalized Individual Development Plan with your primary mentor and a co-mentor to ensure that you are meeting career goals. The candidate must be able to independently and efficiently manage concurrent projects and while possessing a strong commitment to contributing intellectually and interpersonally toward a positive and stimulating lab environment.
Interested candidates should send a cover letter, current CV and contact information for three references to Dr. Parikh (sparikh1@bidmc.harvard.edu). Further details regarding funding and publications can be found at https://connects.catalyst.harvard.edu/Profiles/display/Person/60883  (4.3.19)

Harvard Summer School 2019 - Teaching Assistant, BIOS S-1a: Introduction to Molecular and Cellular Biology
We are seeking several dedicated Teaching Assistants for the Harvard Summer School Course BIOS S-1a: Introduction to Molecular and Cellular Biology. TAs will have a variety of responsibilities both in and out of class (details below). Subject and laboratory expertise in Cell and Molecular Biology is a must. This course requires a larger than typical time commitment from its TAs: Each TA has approximately 12 hours of student contact time per week. In combination with grading and prep, 25 week. In combination with grading and prep, 25-30 hours per week should be expected for the 7 week duration of the course. Additional preparation and administrative support before and after the semester are also required. The additional time requirement is generously compensated.
BIOS S-1a is an exciting opportunity to contribute to a fast-paced, innovative course that draws from the scholarship of teaching and learning to maximize student engagement and achievement. For many students this is their first college-level course. Responsibility, responsiveness, and dedication are essential for success as one of our Teaching Assistants.
Course Information
DATES: June 25th – August 8th 2019 (with some responsibilities before and after)
LECTURE: Tuesday and Thursday, 8:30-11:30AM, Harvard Science Center, Cambridge
*with one make-up session Friday June 28th
LABORATORY: 3 hours, Thursdays or Fridays after lecture, multiple times and location TBA
DISCUSSION: 1.5 hours, Tuesdays after lecture, multiple times and location TBA
OFFICE HOUR: One hour per week, TBA

More info
Those interested in this opportunity should send a brief statement of interest and qualifications to bradley_coleman@hms.harvard.edu and ryan_lee@hms.harvard.edu.
Applications will be accepted until MONDAY APRIL 8th, 2019 (4.2.19)

Simmons University is seeking an adjunct laboratory instructor in Biochemistry for the Fall 2019 semester (September 6-December 6, 2019) on Fridays from 2-6pm.  Duties will included an additional office hour each week.
Laboratory Topics: column chromatography, ELISA, SDS-PAGE, protein purification, enzyme assays, and bioinformatics.
Postdoctoral Fellows interested in gaining teaching experience are strongly encouraged to apply.  Experience in protein purification and enzyme kinetics assays would be beneficial. Ph.D. preferred
Salary range:  $3,800-$4,200 based on prior teaching experience.
Please submit a letter of application, CV, and two professional references (letters can be emailed directly)  to: Jennifer A. Canfield, PH.D., Jennifer.canfield@simmons.edu  (4.1.19)

Postdoctoral Fellowship at Harvard Medical School, Center for Computational and Integrative Biology (CCIB) at Massachusetts General Hospital. We are seeking a self-driven individual with expertise in computational biology to lead projects investigating epigenetics and noncoding RNAs in immunology and fibrosis. This work involves a collaborative approach between bench scientists and computational biologists and will expose the candidate to a wide array of state-of-the-art high-throughput analyses including RNA sequencing (RNA-seq), Assay for Transposase-Accessible Chromatin (ATAC-seq), Precision nuclear Run-On sequencing (PRO-seq), Chromatin Immunoprecipitation/DNA Sequencing (ChIP-Seq, CUT&RUN), high throughput CRISPR screens, sequencing analysis of the microbiome and virome, and the identification and analysis of long noncoding and circular RNAs.
Requirements: The candidate requires a Ph.D. or equivalent doctoral degree in bioinformatics, computational biology or related fields. A candidate with a master’s degree and additional lab or industry experience in computational biology will also be considered. The position requires experience with Linux-based environments and proficiency in Pearl/Python or R. Candidates must be self-driven, organized, work well in teams and have excellent oral and written communication skills.
The successful applicant will conduct research with Dr. Jeffrey
http://jeffreylab.mgh.harvard.edu/ and Dr. Mullen http://mullenlab.mgh.harvard.edu/
Interested candidates should send their cover letter, current curriculum vitae and the contact information for three references to either Dr. Jeffrey (KJeffrey@mgh.harvard.edu) or Dr. Mullen (acmullen@mgh.harvard.edu).
Harvard University and Massachusetts General Hospital are equal opportunity/affirmative action employers. Women and minority applicants are particularly encouraged to apply. (3.24.19)

Preceptor in Stem Cell and Regenerative Biology, Harvard University, Faculty of Arts and Sciences
The Harvard Department of Stem Cell and Regenerative Biology (HSCRB) is the first and only cross-school academic department in both the Harvard Faculty of Arts and Sciences and Harvard Medical School. As a result, the educational mission spans undergraduate, graduate, and medical communities on both the Cambridge and Longwood campuses, as well as the Harvard-affiliated hospitals. Pedagogically, the curriculum emphasis hands-on laboratory experience and inquiry-based learning.
Duties and Responsibilities: Works as a preceptor for undergraduate courses in HSCRB, with responsibility for SCRB 10 (Human Developmental and Regenerative Biology) and two advanced laboratory courses (SCRB 15 – CRISPR Cas9: Precision Genetics and Gene Therapy; SCRB 50 – a new molecular biology lab course to launch spring 2020). Reports to the Associate Director of Education in HSCRB, in close collaboration with the faculty instructors of the courses. This position is for one year, with reappointment possible on a yearly basis for up to eight years (within the eligibility guidelines of the FAS), contingent on performance, curricular need, position availability, and divisional dean authorization. More info and how to apply.

Allergan - Senior Researcher, Research and External Science & Innovation, location is Cambridge, MA.
We are seeking two Ph.D.s and or M.D.s, ideally with post-doctoral experience in an innovative area of neuroscience that complements internal capabilities. This is a unique opportunity within a different kind of pharma company.
Position Summary: The Research and External Science and & Innovation (RESI) team is responsible for identifying, evaluating, and championing the science of external (and internal) projects and partnership opportunities across our therapeutic areas from pre-clinical through development. Our business model is dependent on external sourcing of pipeline opportunities and as such the group has a unique ability to impact the success and future direction of the company. The RESI team evaluates strategic areas of interest, considers creative ways to progress programs through partnerships, and provides scientific leadership to partnered and internal projects. Like a venture capital firm, we evaluate the external landscape and, with our colleagues across the R&D organization, recommend where to invest for our pipeline. A few recent examples include our acquisition and spin of Naurex/Aptinyx for novel anti-depressants, our acquisition of CGRP compounds from Merck, our CRISPR partnership with Editas in ophthalmology, and our partnership with Heptares for novel muscarinic molecules.
The successful candidate will bring neuroscience expertise in an emerging area of science to complement internal capabilities while welcoming the challenge of new areas. While contributing to these activities, the successful candidate will learn drug discovery and development, be challenged with new areas of science, be exposure to a diversity of small biotechs, investment models and venture capital firms.

https://agn.referrals.selectminds.com/jobs/sr-researcher-research-and-external-science-innovation-8345.  (3.22.19)

Brigham & Women’s Hospital Postdoctoral position – The Nasr Lab
One postdoctoral position is available immediately in the laboratory of Dr. Nasr for a highly motivated individual interested in using cryo-EM for the structural studies of viral membrane proteins in nanodiscs. The project will employ a rang of techniques including: membrane protein expression and purification, mammalian cell culture; and nanodisc engineering.  Experience in cryo-EM is preferred but not required.
Applicant should have a recent Ph.D (or anticipate to graduate soon) in a biological field.
The Nasr lab is in the Division of Engineering in Medicine and Renal at Brigham & Women’s Hospital, part of the Harvard Medical School research community at the Longwood Medical Area in Boston, MA. Applicant should email a cover letter and a CV, and arrange for 3 letters of references to be emailed to Dr Nasr ; mahmoud_nasr@hms.harvard.edu.  Please be sure to indicate in your cover letter if you would require visa sponsorship. (3.11.19)

Postdoctoral Research Position in Nephrology; Schlondorff Lab; Beth Israel Deaconess Medical Center/Harvard Medical School
A postdoctoral fellow position is available immediately in the laboratory of Johannes Schlondorff in the Division of Nephrology at Beth Israel Deaconess Medical Center, Boston, Massachusetts.  The laboratory focuses on understanding glomerular podocytes and their role in kidney health and disease, with a particular interest in understanding the development and progression of proteinuric kidney diseases such as focal segmental glomerulosclerosis (FSGS).  Several current projects focus on the role of TRPC6 channel mutations as a genetic cause of FSGS.  The laboratory utilizes an array of techniques spanning protein biochemistry, cell biology, and genetically engineered mouse models in our efforts.
Candidates must have a Ph.D. or M.D./Ph.D. degree with a strong background in cell biology, cell signaling or animal models.  Prior experience in the areas of kidney disease or TRP channel biology is highly desirable, but not necessary.  Applicants should have a record of scientific achievement, be highly self-motivated, have a collaborative attitude, and have excellent organizational and communication skills.
EOE M/F/VET/DISABILITY/GENDER IDENTITY/SEXUAL ORIENTATION
To apply, please send a cover letter and CV to: jschlond@bidmc.harvard.edu. (3.5.19)

Postdoctoral Research Fellow - Cancer Biology – Boston Children’s Hospital
Applications are currently being accepted for a postdoctoral fellow to join the laboratory of Khashayar Vakili at Boston Children’s Hospital/Harvard Medical School, Boston, Massachusetts. Our research focuses on elucidating the biology of liver cancer by analyzing signaling pathways of interest and developing in vitro and in vivo models with a focus on translational studies.
Qualified candidates must have a Ph.D. or M.D./Ph.D. degree with a strong background in advanced molecular biology, genetics, cell culture techniques, animal models, and cancer biology. Candidates must be self-motivated and possess strong communication/organizational skills along with a collaborative attitude. A strong record of scientific achievement is preferred. Salary will be determined based on the candidate’s experience and qualifications.
Please send cover letter, CV, and information for at least three references to:
Alex Lam at alexander.lam@childrens.harvard.edu (3.4.19)

Novartis:  Principal / Sr. Principal Scientific Computing - Multiple Locations
The digital revolution is changing everything, especially in pharmaceuticals where we are collecting more data in our clinical trials than ever before. The question is, what do we do with it? At Novartis, we have over 20 years of untapped data waiting to be explored – thereby unlocking the secrets of the next breakthrough in innovative medicines for patients in need. We are forming a new Scientific Computing and Consulting team that has the opportunity to reimagine how Novartis handles its clinical trial data by enabling the use of state of the art computing infrastructure, leveraging advanced visualization software solutions to dynamically explore our data in an interactive and collaborative manner.
Your Responsibilities:
- Drive the evaluation of business technology, scientific software, novel visualization tools, automated data provisioning pipelines and computation infrastructure improve, increase and enhance the quality and
efficiency of Novartis drug development
- Provide a tight link with the IT organization. Uses influencing skills to ensure infrastructure and decisions made on IT systems meet the needs of the business, i.e. enable the business for the delivery of complex analytics
- Provide software tools and IT infrastructure solutions to enable Quantitative Sciences to work efficiently and effectively to deliver on tasks and make quantitative decisions to trial and or project level activities including dynamic solutions to proactively explore data and deeply characterize patients
- Incorporate evidence from sources of big data (e.g. genomics, biomarkers, digital technology, sensors, imaging and real world evidence)
- Supports the implementation, communication and education of innovative data interrogation / visualization methods
- Builds collaborative working relationships and communicates effectively with Quantitative Sciences partners along with clinical teams promote a greater mindset where associates may leverage each other’s skills in an open and transparent manner
Full details and to apply: 
https://www.novartis.com/careers/career-search/job-details/258285BR (2.26.19)

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center and Harvard Medical School, Whitney Laboratory
Description: A postdoctoral fellow position is available immediately in the Viral Dynamics Laboratory in the area of HIV cure and/or emerging diseases (https://www.whitneylaboratory.com). The fellow will be directly responsible for the conduct of experiments and analysis of data and will work together with other team members in drafting reports and manuscripts.
Requirements: A Ph.D. in immunology, or related field; Must have experience developing and validating complex multi-color flow cytometry panels, performing cell sorting, or performing functional immunology assays with primary cells. Evidence of productivity with first author publications in high impact journals is required. Experience working in BSL2/BSL3 conditions and with human or non-human primate samples is preferred, but not required..
EOE M/F/VET/DISABILITY/GENDER IDENTITY/SEXUAL ORIENTATION
To apply, please send CV to jwhitne2@bidmc.harvard.edu  (2.12.19)


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