Non-Quad Job Opportunities

Job Opportunities
- Please note, these job postings are a courtesy to the HMS Postdoc community. Send any and all inquiries about job opportunities below to the listing organization, company or individual and not to the OPF. Employers: If you would like us to post your job opportunity, submit HERE.-

Scientist I - Cell Biologist | Cancer Research Technology Program | Frederick National Laboratory | Leidos Biomedical Research, Inc.
The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. In addition, the CRTP hosts the Nanotechnology Characterization Laboratory (NCL) which performs and standardizes preclinical efficacy and toxicity testing of nanoparticles intended for cancer therapeutics and diagnostics, and the Antibody Characterization Lab (ACL) which characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research. CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise. Full Job Description (Posted 10.29.19)
 
Postdoctoral Fellowship | Training in Oncology Population Sciences (TOPS) | Dana-Farber & Harvard Cancer Center
The DF/HCC (Dana-Farber/Harvard Cancer Center) is pleased to announce a Postdoctoral Fellowship Training Opportunity called TOPS, Training in Oncology Population Sciences.  Applications are due Monday, January 6, 2020, and accepted fellows will begin their training in July 2020.  Please visit www.TOPSPostdoc.org for more information.  This is a great opportunity for MDs or PhDs to pursue a career in any area of cancer‐related population sciences, including cancer prevention, informatics, or care delivery.  We are now accepting applications at www.TOPSPostdoc.org.
Please direct administrative inquiries to:
Masha Kogan, TOPS Program Administrator, Dana-Farber Cancer Institute 


Research Development and Support Specialist | Center for Translational Neuroscience | Brown University
This position is part of the new Center for Translational Neuroscience (CTN), a collaborative Center between Carney Institute of Brain Science and the Brown Institute for Translational Science. The CTN staff is administered within the Molecular Biology, Cell Biology & Biochemistry (MCB) Department. The new Research Development and Support Specialist will be a member of the CTN team responsible for increasing CTN’s research grant submissions and portfolio, particularly multi-disciplinary, or multi-PI or multi-institutional grant submissions and funding. The incumbent will be responsible for supporting research efforts and initiatives for CTN laboratories and collaborations across laboratories, through identifying, contributing to writing and preparing grant materials, and facilitating the submission of grant proposals. This position will partner with the Director of the CTN and CTN PI’s to develop and build robust collaborative grant submissions. The person in this position will also coordinate scientific events, scientist working meetings (i.e- preparing minutes) and contribute to communications efforts to enhance CTN presence. The position will involve some project support to ensure execution of studies, such as contributing to regulatory documents for animal and human subject studies, and research progress reports.  This position will ensure Faculty research efforts are appropriately supported and will create increased research capabilities. Effective support in this role will also result in well-written and competitive grants submissions.  Apply HERE. (Posted 10.4.19)

Postdoctoral Research Fellow – Extracellular Vesicles and microRNAs | Szabo Lab | Beth Israel Deaconess Medical Center
A postdoctoral position is open in the laboratory of Dr. Gyongyi Szabo at Beth Israel Deaconess Medical Center (BIDMC) / Harvard Medical School to study the role of microRNA and extracellular vesicles (EVs)/exosomes in the pathogenesis of liver diseases. The postdoctoral fellow’s research will focus on extracellular vesicles biogenesis and how EV cargo is modulated in alcoholic and non-alcoholic liver injury in both mice and humans. The role of EVs in cell-to-cell and inter-organ communication will be explored. We are seeking a highly motivated candidate with a strong background in molecular biology and/or with a proven academic publication track record. Experience in exosomes/extracellular vesicles and/or non-coding RNA research is highly desirable.

Required qualifications:

  • PhD and/or MD degree in relevant disciplines within the last 2 years
  • Excellent organization and communication skills
  • Strong analytical skills
  • Ability to work within a collaborative environment

BIDMC and Harvard Medical School are a fantastic research environment with great collaborations and resources for aspiring scientists. Applicants should send a CV and cover letter to gszabo1@bidmc.harvard.edu with subject line Postdoctoral Candidate – EVs and microRNAs (Posted 9.26.19)

Postdoctoral Research Fellow – Immune Signaling in Liver Diseases | Szabo Lab | Beth Israel Deaconess Medical Center
A postdoctoral position is open in the laboratory of Dr. Gyongyi Szabo at Beth Israel Deaconess Medical Center (BIDMC) / Harvard Medical School to study the role of innate immunity, immune cell activation and innate-adaptive immune crosstalk in liver diseases and in the gut-brain-liver axis. We are studying various murine liver injury models of alcoholic hepatitis, non-alcoholic steatohepatitis and their relevance to human patient samples and disease. The postdoctoral fellow’s research will focus on how sterile danger signals from liver injury and gut-derived signals affect the communication between hepatocytes and immune cell populations and the phenotype of circulating neutrophils, monocytes/macrophages, lymphocytes and dendritic cells. We are seeking a highly motivated candidate with a strong background in innate immunity and/or immunology with a proven academic publication track record.

Required qualifications:

  • PhD and/or MD degree in advanced immunology within the last 2 years
  • Excellent organization and communication skills
  • Strong analytical skills
  • Ability to work within a collaborative environment

BIDMC and Harvard Medical School are a fantastic research environment with great collaborations and resources for aspiring scientists. Applicants should send a CV and cover letter to gszabo1@bidmc.harvard.edu with subject line Postdoctoral Candidate – Immune Signaling (Posted 9.26.19)

Multiple Postdoctoral Fellow Positions | The Anderson Lab | Beth-Israel Deconness Medical Center

The Anderson Lab is looking to recruit several postdoctoral fellows interested in pursuing one or more topics that investigate the behavioral neuronal circuits and genetic and immune pathogenesis of autism spectrum disorder:

Mapping the Behavioral Neuronal Circuits of Genetic forms of Autism Spectrum Disorder
The fellow will use the methods illustrated in our publication Krishnan et al. Nature 2017. They will combine stereotaxic brain injections of engineered Cre-conditional AAV viral vectors (shRNA, cDNA, and gRNA/Cas9), engineered Cre-conditional genetic autism model mice, behavioral testing, in vivo (optogenetic slice patch clamp electrophysiology) and in vitro (cell-type and region targeted genetically encoded Ca2+ reporter microscopy in vivo during unrestrained behavior) neuronal circuit analysis, and single and dual site chemogenetics to understand how distinct neuronal circuits underlie the distinct autism-associated problems in sociability and social vocalizations; exaggerated fear behavior; aggressive behavior; and self-injurious behavior found in mouse models of genetic forms of human autism spectrum disorder. They will also use whole brain imaging (clearing/light sheet microscopy; sectioning/whole slide scanning) with temporally locked activity reporters to map the aberrant circuit activities during autism genetics-induced dysregulated behavior. In collaboration with others in the lab, they will use single cell and spatial transcriptomics to understand autism gene-induced dysregulated gene expression of specific cell-type in the circuits as a basis of the behavioral and circuit dysfunction.

Human Postmortem Brain Transcriptomics in Autism Spectrum Disorder
The fellow will be responsible for developing methods to analyze the transcriptome of human postmortem brain tissues from controls and those with autism spectrum disorder, emphasizing immune-related brain tissue pathologies and in separate studies, the behavioral neuronal circuits. They will use single cell (nuclei) sequencing and spatial transcriptomics. Expertise in bioinformatics/computational biology and molecular biology strongly preferred.

Immune Pathogenesis of Autism Spectrum Disorder
The fellow will be responsible for developing mouse models (genetic and maternal immune activation) that reproduce a T-lymphocyte immune neuropathology we recently uncovered in the human autism spectrum disorder postmortem brain (DiStasio et al. Annals of Neurology 2019).

All projects are being conducted in close cooperation with the experts in bioinformatics, providing an excellent opportunity for collaborative research. Harvard Medical School and the Department of Biomedical Informatics also provides for a rich scientific environment, with a number of relevant seminar series, invited speakers, and many neighboring laboratories working on related projects.

PhD in Neuroscience, Physiology, Molecular Biology, or Computational Biology or other related discipline is required. A strong record of publications in the field is desired.

To apply – please send cover letter, curriculum vitae and contact information for at least two references to Matthew P. Anderson, MD, PhD at matthew_anderson@bidmc.harvard.edu. Applications will be considered until the positions are filled. Please specify which projects you are interested in. (Posted 9.25.19)

Assistant Professor | Microbiologist | Department of Biology | Rhodes College | 2000 North Parkway Memphis, TN
The Department of Biology at Rhodes College seeks qualified applicants for a tenure-track assistant professor position in Microbiology to begin in August of 2020.Candidates must have a Ph.D., research experience in microbiology, and a commitment to undergraduate teaching and research. Laboratory start-up funds will be provided to support the expected development of a productive research program. The teaching responsibility of five courses per year (labs are counted as a full course) will normally include Microbiology and Microbiology Laboratory for Biology majors, plus participation in the introductory biology course covering cellular and molecular biology. Other teaching opportunities may include Senior Seminar, a course for non-science majors, or an additional course in the candidate’s area of specialty. The successful applicant will have the opportunity to participate in the interdisciplinary programs of the College.

Please apply online at jobs.rhodes.edu. A complete application will include 1) a cover letter that addresses the strengths the candidate will bring as a teacher and scholar to a liberal arts college environment; 2) a curriculum vitae; 3) copy of graduate transcript, 4) the names and contact information for three references; 5) a statement of teaching philosophy, 6) a research plan, and 7) a separate statement that addresses how your experiences with teaching, scholarship, and/or service will contribute to a college community that includes a commitment to diversity and inclusion as one of its core values. Review of completed applications will begin October 7, 2019 and will continue until the position is filled.The online application system will solicit letters electronically from the candidate’s recommenders, once their contact information has been entered by the candidate and all other required application materials have been submitted. Candidates from backgrounds typically underrepresented in higher education are strongly encouraged to apply. Background checks are required before candidates can be brought to campus for interviews. View full job posting HERE. (Posted 9.23.19)

Assistant Professor | Invertebrate Biologist | Department of Biology | Rhodes College | 2000 North Parkway Memphis, TN
The Department of Biology at Rhodes College seeks qualified applicants for a tenure-track faculty position as an Invertebrate Biologist to begin in August of 2020. Candidates must have a Ph.D., research experience in invertebrate biology, and a commitment to undergraduate teaching and research. Laboratory start-up funds will be provided to support the expected development of a productive research program. The teaching responsibility of five courses per year (labs are counted as a full course) will normally include a course with laboratory for Biology majors that is related to the candidate’s area of specialty, plus participation in the introductory biology course and laboratory covering organismal/ecological biology. Other teaching opportunities may include Senior Seminar, a course for non-science majors, or an additional course in the candidate’s area of specialty. The successful applicant will need to show an interest in contributing to the interdisciplinary environmental science program of the College, and we encourage applications from individuals whose interests go beyond traditional disciplinary boundaries.

Please apply online at job.rhodes.edu. A complete application will include 1) a cover letter that addresses the strengths the candidate will bring as a teacher and scholar to a liberal arts college environment; 2) a curriculum vitae; 3) copy of graduate transcript, 4) the names and contact information for three references; 5) a statement of teaching philosophy, 6) a research plan, and 7) a separate statement that addresses how your experiences with teaching, scholarship, and/or service will contribute to a college community that includes a commitment to diversity and inclusion as one of its core values. Review of completed applications will begin October 9, 2019 and will continue until the position is filled. The online application system will solicit letters electronically from the candidate’s recommenders, once their contact information has been entered by the candidate and all other required application materials have been submitted. Candidates from backgrounds typically underrepresented in higher education are strongly encouraged to apply. Background checks are required before candidates can be brought to campus for interviews. View ful job posting HERE. (Posted 9.23.19)

BioBuilder Master Teacher | BioBuilder Educational Foundation
BioBuilder is a nonprofit organization that takes a comprehensive approach to the emerging field of synthetic biology, providing exceptional programming available for students and educators alike. The goal is to teach these teachers how to use the BioBuilder curriculum to teach synthetic biology. Biobuilder is currently looking for Graduate students and/or post-docs with a background in biochemistry, molecular genetics, bioengineering and/or synthetic biology who are interested in a unique, short-term teaching opportunity. Candidates will lead three-day summer workshops for community college and high school teachers.
Commitment required (~2 weeks during the summer):
• Learn the BioBuilder workshop curriculum by running the experiments yourself (an all-inclusive kit and textbook is provided) and participating in a “Who is BioBuilder” webinar.
• Work with BioBuilder headquarters to organize workshop logistics at your site.
• Prepare materials for the workshop.
• Co-lead the workshop with a local high school teacher who has experience teaching BioBuilder content in their classrooms.

Compensation is $400 to learn the curriculum and $600/3-day workshop. To apply please submit a cover letter outlining why you believe you are a great fit for this role, and a current resume to Dr. Natalie Kuldell, info@biobuilder.org. Include your name and “BioBuilder Master Teacher” in the subject line of your email. Learn more at www.biobuilder.org. More information HERE. (Posted 9.23.19)

Senior Scientist - Mathematical Modeler | Applied BioMath | Concord, MA or Oakland, CA
AppliedBioMath is currently seeking a talented and innovative Senior Scientist, Mathematical Modeler to join their team in Concord, MA or Oakland, CA. The ideal candidate will work closely with Pharma and Biotech teams to build fit-for-purpose mechanistic pharmacokinetic/pharmacodynamic (PKPD) and Quantitative systems pharmacology (QSP) models that help drive decisions in drug discovery and development. Models may describe pharmacokinetics, pharmacodynamics, signaling pathways (intra- and cell-cell signaling), disease mechanisms (description and mechanistic), and drug toxicities.

Responsibilities:

  • Participate as representative on multiple customer and internal project teams and work with biologists and project lead to translate biological/mechanistic understanding to mathematical models
  • Develop, calibrate, and analyze mathematical models 
  • Clearly communicate modeling results to customers with diverse background
  • Write reports for the modeling work
  • Perform internal review and QC of other colleagues’ modeling work
  • Develop new algorithms, methodologies, protocols and test procedures that contribute to internal & external partner goals
  • Participate in internal and external team discussions, and contribute to project team strategy, especially the computational strategy
  • Perform literature searches and text mining to help inform models
  • Help establish visibility for ABM’s modeling expertise by presenting at external meetings and draft publications
  • Write grants to develop ABM internal QSP models and modeling capacities

Qualifications:

  •  PhD or equivalent in biomedical engineering, chemical engineering, pharmaceutical sciences,  biophysics, applied mathematics, biology, biochemistry or related field
  • Experience with PKPD model, QSP model, differential equation based models to describe biological systems
  • Expert in differential equations and coding with MatLab or other relevant languages
  • Deep understanding and ability to independently implement in standard model analysis (Monte Carlo simulation, sensitivity analysis, parameter optimization)
  • Basic understanding of pharmacokinetics and pharmacodynamics for small and large molecules and drug candidates
  • Experience in building models for oncology, immunology, immuno-oncology, or neuroscience is highly desired
  • Experience with population PKPD models, statistical modeling is a plus
  • Industry experience at pharmaceutical or biotech companies is highly preferred
  • Strong interpersonal and communication skills, experience working with multidisciplinary teams and leading projects
  • Experience managing workload and timeline and track record of delivering work on time
  • Record of scientific achievement through peer-reviewed publications, invited oral presentations, or patents

Email careers@appliedbiomath.com to apply. View open positions and full job descriptions HERE. (Posted 9.18.19)

Research Fellow In Computational Genomics and Genetics | Division of Nephrology | Boston Children’s Hospital
A full-time Research Fellow position is available in a newly established laboratory of Dr. Dongwon Lee in the Division of Nephrology at Boston Children’s Hospital (BCH). BCH is a Harvard Medical School (HMS) affiliated hospital. The laboratory studies disease-associated genetic variants using computational approaches with a specific focus on transcriptional regulatory mechanisms. Dr. Lee has developed several machine-learning based methods for predicting regulatory elements and regulatory variants (Lee et al., Nature Genetics 2015). He also showed that these predicted regulatory variants explain a significant proportion of heritability in a tissue-specific manner (Lee et al., Genome Research 2018). The laboratory will continue to develop computational methods to model regulatory control of human diseases, by incorporating improved machine-learning algorithms and single-cell multi-omic data (genomic, transcriptomic, and epigenomic.) New computational frameworks will help discover the molecular mechanisms driving the development and progression of human diseases.
Requirements
1) The ideal applicant should have received a Ph.D. degree within 12 months or expect to do so within the following 12 months in computational biology, bioinformatics, biostatistics, computer science, or other related fields.
2) Strong programming skills in Python, C/C++, R or equivalent are required.
3) Experience with Unix/Linux and working with large genetic and genomic data in a cluster-computing environment is preferred.
4) Excellent written and verbal communication skills, and willingness to write grant proposals and manuscripts are necessary.
How to apply
Interested candidates should send a CV and one-page research narrative to:
Email: Dongwon.Lee@childrens.harvard.edu
Dongwon Lee, PhD
Division of Nephrology
Boston Children’s Hospital

(Posted 9.6.19)

Vor Biopharma
Vor Biopharma is a preclinical biotechnology company founded by leading scientists (including Siddhartha Mukherjee), and backed by top venture capital firms. Vor is developing targeted therapies based on engineered hematopoietic stem cells that are designed to transform outcomes for cancer patients. Vor uses gene engineering tools to develop novel cell therapies for the treatment of hematological malignancies. Vor is currently recruiting critical-thinking and technically sound molecular/cell biologists looking to make the jump to industry. Visit their website for more information HERE.

Associate Scientist/Sr Associate Scientist, Target Discovery | Vor Biopharma
The successful candidate will contribute
to the discovery of novel targets of Vor’s innovative pipeline.This will involve working within a team environment to execute experimental plans requiring skills in fundamental molecular biology, cellular engineering, hematopoietic stem cell, T cell and myeloid cell biology.

Key areas of responsibility
Routinely perform culture, editing and manipulation of primary cells and cell lines
Perform cellbiology, molecularbiology and biochemical assays including gene editing, viral transduction, DNA and RNA extraction, PCR/qPCR, flow cytometry and western blot
Participate in the design of experiments, the interpretation of data, and lead trouble shooting with oversight from senior scientific personnel
Participate in drafting standard operating procedures, work instructions, test methods, study protocols, and technical reports
Participate in drafting presentations and progress at regular internal research meetings
Maintain a clear, detailed laboratory notebook to document all experiments and findings
Comply with best safety practices

Qualifications
Bachelor’s or Master’s Degree in fields such as biochemistry/molecular biology, immunology, cancer biology, bioengineering, or related discipline is required (title and compensation commensurate with experience) or Master’s Degree with 2+ years of laboratory experience in an industry settingindustry preferred
Experience with mammalian cell culture
Experience with ex vivo genetic manipulation of hematopoietic stem cell or primary T cells, using gene editing tools (CRISPR, TALEN, or ZFN) and/or viral gene delivery
Excellent communication, organization, and technical writing skills
Strong problem-solving skills and the ability to work independently in startup environment
Immediate availability

Full job description HERE. Inquiries can be sent to: careers@vorbiopharma.com (Posted 9.5.19)

Associate Scientist, Molecular and Cell Biology | Vor Biopharma
The successful candidate will contribute to advancing Vor’s
engineered hematopoietic stem cell products. This will involve working within a team environment to execute experimental plans requiring skills in fundamental molecular biology, cellular engineering, and hematopoietic stem cell biology.

Key areas of responsibility
Routinely perform culture, editing and manipulation of primary cells and cell lines.
Conduct cell-based assays such as flow cytometry and colony-forming assay to evaluate phenotypic changes in gene modified cells.
Perform molecular biology work such as DNA and RNA extraction, PCR/qPCR, and next-generation sequencing library preparation, as well as protein-based assays such-as Western blot.
Implement sensitive genome-wide assays for various types of mutations and chromosomal rearrangements.
Processing of cells and tissues from xeno-transplanted animals.
Participate in the design of experiments, the interpretation of data, and lead trouble shooting with oversight from senior scientific personnel.
Participate in drafting standard operating procedures, work instructions, test methods, study protocols, and technical reports.
Participate in drafting presentations and progress at regular internal research meetings.
Maintain a clear, detailed laboratory notebook to document all experiments and findings.
Comply with best safety practices.

Qualifications

Bachelor’s or Master’s Degree in fields such as biochemistry/molecular biology, immunology, cancer biology, bioengineering, or related discipline is required (title and compensation commensurate with experience) or Bachelor’s Degree with 3+ years’ experience, or; Master’s Degree with 2+ years of laboratory experience in an academic or industry setting (industry preferred)
Experience with mammalian cell culture
Experience using gene editing tools (CRISPR, TALEN, or ZFN) as well as previous experience in gene editing
Previous experience identifying off-target sites is a plus
Experience in hematopoietic stem cell or CAR-T relevant experimental techniques, including both in vitro cellular assays and in vivo transplant models is highly desirable.

Full job description HERE. Inquiries can be sent to: careers@vorbiopharma.com (Posted 9.5.19)

Scientist/Sr. Scientist Molecular & Cell Biology | Vor Biopharma
The successful candidate will lead a project aimed at developing molecular biology tools to evaluate off target profiles for Vor’s engineered hematopoietic stem cell products. This will involve design and execution of an experimental plan comprised of fundamental molecular biology, cellular engineering and cellular and biochemical assay optimization to identify genome editing efficieny of CRISPR and other genome editing nucleases and their off-targets.

Key areas of responsibility
Develop and optimize assays to identify efficieny of genome editing nucleases in hematopoietic stem cells and other cell lines.
Prepare sequencing libraries for amplicon sequencing, GUIDE-seq, Digenome, Hybrid Capture, CIRCLE-seq or other off-target analysis approaches.
Profile gene expression signatures in bulk or single cell populations using qPCR, ddPCR and RNA-seq.
Generate editing reagents using Gibson, USER assembly or other relevant cloning strategies.
Primary/stem cell (human CD34+HSPCs, iPSC) and mammalian cell line cultureCoordinate with internal collaborators andexternal contract research as needed.
Design experiments, interpret data, and problem solve with a high level of independence and creativity to advance company's hematopoietic stem cell therapy platform.
Review, interpret and communicate data across functions within the research and/or project teams.
Understands project timelines and deliverables and plans/coordinates project work accordingly with departmental, functional and external stakeholders.
Draft standard operating procedures, work instructions, test methods, study protocols, and technicalreports
Create presentations and present progress to senior management.

Qualifications

  • Ph.D. in biological science or related discipline with 3-6 years of postdoctorate experience or 2-4 years of experience in biotech or pharma.
  • Strong scientific background and publication record with proven high levels of performance.
  • Previous experience identifying off-target sites using GUIDE-seq, Digenome-seq, CIRCLEseq or other is strongly preferred.
  • Lab skills and technical background of gene editing tools and principles (ZFN, TALENs, CRISPR, or DNA base editors). Optimizing CRISPR/Cas9-based gene editing is strongly preferred.
  • Library preparation for whole genome, amplicon sequencing or transcriptome library preparation – bulk or single cell RNA-seq – is strongly preferred
  • Experience in primary/stem cell and mammalian cell line culture (iPSC or HSPC experience a plus)

View full job description HERE. Inquiries can be sent to: careers@vorbiopharma.com (Posted (9.5.19)

Scientist/Sr. Scientist in Genome Engineering | Vor Biopharma
The successful candidate will lead a project aimed at developing
innovative ways to engineer Vor’snew generation of hematopoietic stem cell productsusing multiplex gene editing systems. This will involve design and execution of experimental planscomprised of fundamental molecularbiology techniques and biochemical/biophysical assays.

Key areas of responsibility

  • Evaluate existing gene editing systems (including ZFN, TALENs and CRISPR systems) and design/optimize new systems to enable multiplex genome editing capabilities.
  • Develop in vitro molecular biology and biochemical assays to analyze gene editing outcomes.
  • Design experiments, interpret data, and problem solve with a high level of independence and creativity to advance company's hematopoietic stem cell therapy platform.
  • Deliver results by creating presentations to effectively communicate progress to senior management.
  • Collaborate cross functionally between research groups.
  • Draft standard operating procedures, work instructions, test methods, study protocols, and technical reports.
  • Maintain a clear, detailed laboratory notebook to document all experiments/findings and comply with best safety practices.

Qualifications

  • PhD is required: Strong preference inmolecular biology, biochemistry, or related discipline.
  • 3-6 years of experience in postdoctoral training or in industry setting preferred.
  • Deep understanding of & hands on experience with gene editingandmolecular biology (including RNA/DNA extraction, gRNA design, molecular cloning, qPCR).
  • Experience with DNA repair, enzyme kinetics, biochemistry and mammalian cell culture.

Full job description HERE. Inquiries can be sent to: careers@vorbiopharma.com (Posted 9.5.19)

Scientist/Sr. Scientist, in vivoBiology | Vor Biopharma
The successful candidate will lead a project aimed at developing & optimizing Vor's engineered
hematopoietic stem cell products. This will involve design and execution of an experimental plan comprised of fundamental molecular biology, cellular engineering, hematopoietic stem cell biology, and humanized mouse model approaches.

Key areas of responsibility

  • Develop assays (in vitro & in vivo) to study hematopoietic stem cell behavior in response to cellular engineering.
  • Coordinate in vitro and in vivo testing at external contract research organizations and with other collaborators, as needed.
  • Design experiments, interpret data, and problem solve with a high level of independence and creativity to advance company's hematopoietic stem cell therapy platform.
  • Draft standard operating procedures, work instructions, test methods, study protocols, and technical reports.
  • Create presentations and present progress to senior management
  • Maintain a clear, detailed laboratory notebook to document all experiments and findings.
  • Comply with best safety practices.

Qualifications

  • PhD is required: in fields such as molecular biology, cellular biology, bioengineering, or related discipline.
  • 2+ years of experience postdoctoral training or in industry setting preferred.
  • Deep understanding of & hands on experience with studying hematopoietic stem cell biology required.
  • Demonstrated experience with NSG and related mouse models for studying hematopoietic stem cell function.
  • Experience with mammalian cell culture, including hematopoietic stem cells, and carrying out validation studies in vitro and in vivo, including FACS, ELISA, immuno-blotting, and immunohistochemistry.
  • Experience using gene editing tools (CRISPR, TALEN, or ZFN) is a plus.

Full job description HERE. Inquiries can be sent to: careers@vorbiopharma.com (Posted 9.5.19)

Assistant Professor in Microbiology | Wheaton College
Wheaton College (Norton, MA) seeks to hire a tenure-track Assistant Professor of Biology with expertise in microbiology. The 3/2 teaching responsibilities include a course in general microbiology, introductory biology (Cells & Genes and/or Evolution & Ecology), and upperlevel courses in the candidate’s areas of expertise. The successful candidate will play an active role in guiding the future of the Biology and other Bioscience majors (Biochemistry, Bioinformatics, Environmental Science, and Neuroscience), maintain an active research program that engages undergraduates on multiple levels, and complement / add to existing strengths in the department. Successful candidates must provide clear evidence of, or potential for, excellence in teaching and mentoring of undergraduate researchers as well as a commitment to equity and inclusion in higher education. The successful candidate must have a Ph.D. at the time of appointment. 
Wheaton strives to be a community supportive of diverse perspectives and identities through inclusive and equitable institutional practices. Candidates should describe in their letter of application how they will support the College’s commitment to diversity, equity, and inclusion, whether through their teaching, scholarship, and/or service. Applicants should submit a cover letter, CV, statement of research interests, statement of teaching philosophy, list of potential courses, and contact information for three reference/letters of recommendation providers to be submitted online through the Wheaton College HR Department at http://jobs.wheatoncollege.edu/postings/2750. Applications will be accepted until September 23, 2019 or until the position is filled. (Posted 9.5.19)

Faculty Member, Pathogen-Associated Malignancies | Fred Hutchinson Cancer Research Center | Integrated Research Centers | Seattle, WA
The Fred Hutchinson Cancer Research Center seeks to expand research on PAMs, including Hepatitis viruses and invites applications to fill a full-time laboratory-based faculty position. Encouraged to apply are virology, microbiology, or immunology faculty members wishing to establish an independent lab working on a virus or bacteria that is associated with cancer. Applicants from PhD, MD/PhD, or MD scientists will be considered at any rank. Please provide a curriculum vitae, a two to three-page research plan, three recent publications, and three letters of reference. The applicant review process begins as applications arrive and any application received by October 30th, 2019 will be guaranteed consideration for the position. More information HERE and to apply HERE. (Posted 8.23.19)

 

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